Radiomics combined with clinical characteristics predicted the progression-free survival time in first-line targeted therapy for advanced non-small cell lung cancer with EGFR mutation

Table 2 The top ten features and the corresponding mean (± SD) value (or median (IQR)) and the p-value between the slow and fast progression groups

Feature category		Feature	Slow-progress	Fast-progress	p-value
Shape-based (n = 4)		Elongation	0.76 ± 0.12	0.71 ± 0.13	0.067^a
		Least Axis Length	30.06 ± 11.91	20.53 ± 8.85	0.234^a
		Flatness	0.59 ± 0.14	0.55 ± 0.13	0.229^a
		Major Axis Length	52.25 (19.52,110.61)	46.56 (23.28,145.60)	0.858^b
First-order based (n = 1)		Inter quartile range	140 (36,560)	154 (42,385)	0.962^b
Texture	GLSZM (n = 1)	Small Area Emphasis	0.68 ± 0.04	0.70 ± 0.03	0.003^a
Texture	GLCM (n = 1)	Difference variance	14.59 ± 6.63	18.16 ± 8.71	0.024^a
Clinical based (n = 3)		Smoke	–	–	0.238^c
		Mutation	–	–	0.030^c
		Outcome	–	–	0.000^c

ISSN: 1756-0500