From: Unspecified opioids among opioid overdoses in Oslo, Norway
Unspecified opioids | Long-acting opioids | Heroin | p-value for comparison across all three groups | p-value for pairwise comparisons | |||
---|---|---|---|---|---|---|---|
n (%) | n (%) | n (%) | Unspecified vs. long-acting | Unspecified vs. heroin | Long-acting vs. heroin | ||
Males | 369 (80.4) | 99 (73.9) | 1424 (79.6) | 0.24 | |||
Age (years)a,b | 39 (33–46) | 44 (36–51) | 38 (30–46) | < 0.001 | 0.001 | 0.013 | < 0.001 |
Observation time (h:min)a | 5:29 (3:49–7:01) | 4:54 (2:45–6:48) | 4:49 (2:48–6:16) | < 0.001 | 0.070 | < 0.001 | 0.37 |
GCS at presentationa,c | 13 (10–14) | 14 (13–15) | 14 (13–15) | < 0.001 | < 0.001 | < 0.001 | 0.54 |
Lowest GCSa,d | 10 (9–13) | 13 (11–14) | 13 (10–14) | < 0.001 | < 0.001 | < 0.001 | 0.46 |
Bradypnoea (RR < 12/min) | 80 (17.4) | 26 (19.4) | 504 (28.2) | < 0.001 | 0.69 | < 0.001 | 0.036 |
Tachycardia (HR ≥ 100/min) | 51 (11.1) | 14 (10.4) | 277 (15.5) | 0.024 | 0.95 | 0.022 | 0.15 |
Bradycardia (HR < 50/min) | 9 (2.0) | 3 (2.2) | 45 (2.5) | 0.78 | |||
Hypertension (BP ≥ 180 mmHg) | 2 (0.4) | 1 (0.7) | 10 (0.6) | 0.90 | |||
Hypotension (BP ≤ 90 mmHg) | 21 (4.6) | 5 (3.7) | 72 (4.0) | 0.85 | |||
Hyperthermia (temp ≥ 39.0 °C) | 5 (1.1) | 1 (0.7) | 16 (0.9) | 0.91 | |||
Hypothermia (temp < 35.0 °C) | 66 (14.4) | 15 (11.2) | 149 (8.3) | < 0.001 | 0.42 | < 0.001 | 0.33 |
Naloxone treatment | 107 (23.3) | 17 (12.7) | 540 (30.2) | < 0.001 | 0.011 | 0.004 | < 0.001 |
Transferred to hospital | 75 (16.3) | 25 (18.7) | 180 (10.1) | < 0.001 | 0.62 | < 0.001 | 0.003 |
Total | 459 (100) | 134 (100) | 1788 (100) |