Fig. 2

Comparison of signal intensities of candidate molecules between the clinically mild and severe groups in each cohort. A DHA, B Lyso PE, C PI, D PA. A–D The left side is the signal intensity plots of each molecule (cohort 1: red plots, 2nd cohort 2: blue plots). In each plot, “0” is the clinically mild group, and “1” is the clinically severe group. The right side shows a DESI-IMS image of each molecule from each biopsy sample of cohort 2. DESI-IMS desorption electrospray ionization imaging mass spectrometry; DHA docosahexaenoic acid; LysoPE lysophosphatidylethanolamine; PI phosphatidylinositol; PA phosphatidic acid