Table 1 CD138 and Kappa immunostaining patterns in various tissues
Organ/tissue | CD138 | Kappa |
|---|---|---|
Small intestine | ||
 Plasmacytes | Peyer’s patches (++) Lamina propria of villi (++) | Peyer’s patches (++) Lamina propria of villi (++) |
 Enterocytes | Enterocytes (crypts > surface) (Neg to ++) | (Neg) |
Liver | ||
 Hepatocytes | Sinusoidal pattern/basolateral hepatocytes (++) Hepatocyte cytoplasm (+) | (Neg) |
 Bile duct | Biliary epithelium (++) | (Neg) |
Kidney | ||
 Glomeruli | Bowman’s capsule (+) Cellular immunostaining common (++) | (Neg) Cellular immunostaining rare to scattered, detected in only 4 of 6 animals (+/++) |
 Tubules/ducts | Cortex > medulla (+/++) | (Neg) |
 Pelvis | Urothelium (++) | (Neg) |
Skin | ||
 Epidermis | (++) | (Neg) |
 Follicles/adnexa | Follicular epithelium (++) Sebaceous glands (++) | (Neg) |
Lung | ||
 Airways | Surface epithelium (++) | (Neg) |
 Alveolar epithelium | Type 2 cells (++) Type 1 cell (+) | (Neg) |