Table 3 Changes in pain free walking distance during follow up, according to age, physical activity, comorbidities and drug co-treatment
n | Visit I (baseline) | Visit II (3 months) | Visit III (6 months) | p-value | |
|---|---|---|---|---|---|
According to age | |||||
50–64 years | 285 | 346 (312–380) | 640 (594–687) | 819 (759–878) | 0.047 |
65–74 years | 487 | 275 (253–296) | 569 (538–600) | 761 (720–802) | < 0.02 |
≥ 75 years | 243 | 239 (208–269) | 510 (472–548) | 671 (622–720) | NS |
According to smoking status | |||||
Former smokers | 542 | 300 (244–363) | 514 (456–599) | 608 (578–692) | < 0.03 |
Current smokers (at 6 months) | 143 | 259 (160–340) | 420 (448–579) | 581 (543–673) | < 0.03 |
Non-smokers | 271 | 265 (233–296) | 543 (508–577) | 728 (678–779) | < 0.04 |
According to changes in physical activity | |||||
In patients with no increase in physical activity | 212 | 262 (242–282) | 499 (453–544) | 703 (645–761) | < 0.05 |
In patients who have increased their physical activity during follow up | 542 | 274 (252–295) | 555 (525–585) | 750 (711–789) | < 0.02 |
According to comorbidities | |||||
In the presence of hypertension | 873 | 288 (270–306) | 563 (540–586) | 740 (710–769) | < 0.02 |
In the presence of type 2 diabetes | 545 | 266 (247–284) | 542 (512–571) | 712 (672–751) | < 0.03 |
In the presence of dyslipidaemia | 108 | 331 (269–393) | 563 (509–617) | 800 (706–893) | < 0.03 |
According to PAD drug co-treatment | |||||
Cilostazol 100 mg monotherapy | 328 | 345 (311–379) | 650 (603–698) | 832 (782–883) | < 0.01 |
Cilostazol 50 mg monotherapy | 249 | 298 (264–331) | 646 (600–693) | 791 (738- 843) | < 0.03 |
Cilostazol 50 mg and acetylsalicylic acid | 126 | 358 (301–415) | 599 (534–664) | 742 (652–831) | < 0.04 |
Cilostazol 100 mg and acetylsalicylic acid | 97 | 233 (188–279) | 569 (488–650) | 836 (709–964) | < 0.05 |
Cilostazol 50 mg and clopidogrel | 80 | 255 (221–290) | 513 (442–583) | 742 (640–845) | < 0.04 |
Cilostazol 100 mg and clopidogrel | 135 | 279 (235–323) | 539 (468–609) | 711 (626–796) | < 0.03 |