Fig. 2
From: Notch1 signaling is limited in healthy mature kidneys in vivo
Visualization of past Notch1 signaling in ‘healthy’ mature kidneys
(a) Fluorescent examination of ‘healthy’ mature kidney at a low magnification. Note that tdsRed was expressed in both the cortex and medulla specifically in N1-Gal4VP16; UAS-Cre; R26GRR mice. (b) Fluorescent examination of ‘healthy’ mature kidney at a high magnification. Note that tdsRed was expressed in the tubules. (c) Immunohistochemistry for dsRed showed that proximal tubular epithelial cells (arrowheads) and podocytes (arrow) had a Notch1 signal in concordance with previous reports.