Table 1 Demographic and clinic-pathological characteristics of the study population
From: ATG5 as biomarker for early detection of malignant mesothelioma
|  | Ctrl (n = 16) | Exp (n = 33) | MPM (n = 32) | Pre-diagnostic samples (n = 7) | Total (n = 88) | p-Value |
|---|---|---|---|---|---|---|
Age (years) | 60.8 ± 17.8 | 70.2 ± 7.7 | 70.7 ± 6.7 | 75.9 ± 4.7 | 69.1 ± 10.6 | p = 0.002 |
Gender (M/F) | 13/3 | 32/1 | 29/3 | 7/0 | 81/7 | p = 0.228 |
Smoking (n/%) Yes No Former | 6 (38) 5 (31) 5 (31) | 1 (4) 16 (48) 16 (48) | 5 (16) 11 (34) 16 (50) | 0 (0) 5 (71) 2 (29) | 12 (14) 37 (42) 39 (44) | p = 0.025 |
Asbestos exposure Duration work (years) Cf (ff/l) × years ARD (Yes/No/ND) PD (Yes/No/ND) | - - - - | 25.9 ± 10.3 3.5 ± 5.8 22/11/0 17/16/0 | 24.0 ± 12.5 5.8 ± 7.6 11/2/19 1/11/20 | 19.0 ± 1.79.3 ± 8.4 7/0/0 1/6/0 | 25.0 ± 11.4 4.5 ± 6.7 40/13/19 19/33/20 | p = 0.215 p = 0.057 p = 0.001 p = 0.0005 |
Histotypes (n/%) Epithelial Biphasic Sarcomatoid | Â | Â | 19 (62) 6 (19) 6 (19) | 4 (57) 0 (0) 3 (43) | 23 (60) 6 (16) 9 (24) | Â |
Overall survival (months) | - | - | 14.6 ± 9.8 |  |  |  |