Fig. 2
From: Transcutaneous measurement of renal function in two rodent models of obstructive nephropathy
The impact of bilateral ureteral obstruction on tGFR and pCreatinine. Rats were subjected to 24 h of BUO (24hO) followed by release (24 h) of the obstruction, or Sham surgery, and monitored for an additional 11 days. Changes in kidney function were monitored using plasma Creatinine (µmol/L) and transcutaneous GFR (ml/min/100g BW) measurements. (A) Timeline of experiment. (B) tGFR in BUO-R (n = 6–7) and Sham rats (n = 4–5). (C) pCreatinine levels in BUO-R (n = 7) and Sham rats (n = 5). All time points are compared to the corresponding intragroup baseline, data are presented as mean ± SEM. *P < 0.05 compared to BUO baseline. #P < 0.05 compared to Sham baseline