Table 1 Analysis of histopathological changes in epidermis before and after treatment
Epidermis | ||||||
|---|---|---|---|---|---|---|
Acanthosis | Exocytosis | Spongiosis | Hyperkeratosis | Dyskeratosis | Ulcer | |
APG + glucantime | ||||||
Before; n (%) | 13 (86.7) | 4 (26.7) | 5 (33.3) | 11 (73.3) | 6 (40.0) | 7 (46.6) |
After; n (%) | 8 (53.3) | 1 (06.6) | 2 (13.3) | 7 (46.6) | 2 (13.3) | 1 (06.6) |
p-value | 0.001 | 0.01 | 0.03 | 0.02 | 0.013 | 0.001 |
Glucantime | ||||||
Before; n (%) | 12 (80.0) | 5 (33.3) | 6 (40.0) | 10 (66.6) | 8 (53.3) | 6 (40.0) |
After; n (%) | 8 (53.3) | 3 (20.0) | 4 (26.7) | 9 (60.0) | 5 (33.3) | 3 (20.0) |
p-value | 0.02 | 0.06 | 0.05 | 0.15 | 0.04 | 0.03 |