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Table 5 ROC curve statistical evaluation for biomarker efficacy in MS patients

From: The effect of glatiramer acetate, IFNβ-1a, fingolimod, and dimethyl fumarate on the expression of T-bet, IFN-γ, and MEG3 in PBMC of RRMS patients

ROC curve details

T-bet

IFN-γ

MEG3

AUC

0.81

0.73

0.69

Cut-off point

> 0.6135

> 0.001780

> 0.000185

95% CI

0.5636 to 1.000

0.4915 to 0.9619

0.4442 to 0.9440

Std. error

0.1257

0.1200

0.1275

Sensitivity%

80.00

100.0

100.0

Specificity%

90.00

46.67

41.18

P-value

0.0352

0.1378

0.1961