Fig. 2

Augmenting native AGR homology data with additional species. Homology data from additional species may be added to existing AGR-supplied data in the local environment. This figure illustrates generalized mapping from additional resources. For example, if (1) genes A and B are derived from a missing species, they are added to AON gene table. (2) Pairwise homology information is simultaneously added to the AGR orthology table. In this example, GeneWeaver homology clusters are decomposed into their constitutive pairwise relationships. If a gene is not represented in AGR, it is not added (ex: F) in the pairwise orthology table. Relationships are not added if they connect two genes where neither is from the missing species. (3) For producing endpoints that integrate into GeneWeaver, pairwise relationships are aggregated into homology clusters