Fig. 3
From: Aon: a service to augment Alliance Genome Resource data with additional species
Example endpoint to retrieve orthologous genes. Here we demonstrate the endpoint get_ortholog_by_to_and_from_species, in which all orthologs from an added species, Macaca mulatta, to an existing AGR species, Homo sapiens, are retrieved by AON. To do this, AON translates the species name into species ID numbers, retrieves all genes from each species, and queries the ortholog table with these genes, from Macaca mulatta to Homo sapiens. The result is a subset of the ortholog table containing relationships between these two species. The genes identified by these relationships are orthologous. This figure illustrates how the software can transition between different accession numbers, Entrez accession IDs for Macaca mulatta and species-specific HGNC for Homo sapiens