Parameter | Healthy controls (n = 36) mean ± SD | TPO + controls (n = 25) mean ± SD | TPO + RPL (n = 32) mean ± SD | P value | |||
---|---|---|---|---|---|---|---|
TPO + controls vs. TPO + RPL | Healthy controls vs. TPO + RPL | Healthy controls vs. TPO + controls | |||||
Age | 29.86 ± 5.12 | 33.22 ± 4.64 | 32.81 ± 5.01 | NS | NS | NS | |
Weight (kg) | 64.96 ± 12.1 | 69.71 ± 11.9 | 68.32 ± 9.81 | NS | NS | NS | |
Height (cm) | 157.3 ± 5.61 | 158.8 ± 6.66 | 160.3 ± 5.92 | NS | NS | NS | |
BMI (kg/m2) | 26.25 ± 3.86 | 27.4 ± 3.98 | 26.58 ± 3.62 | NS | NS | NS | |
Number of miscarriages | 0.28 ± 0.6137 | 3.226 ± 0.8046 | < 0.0001 | ||||
Number of live births | 2.000 ± 0.8619 | 1.480 ± 0.6532 | 0.0096 | ||||
RPL type | Primary | 19 | |||||
Secondary | 13 | ||||||
TSH (mIU/L) | 2.12 ± 1.02 | 4.83 ± 1.82 | 5.41 ± 1.38 | NS | < 0.0001 | 0.0019 | |
Anti-TPO | 0 | 25 | 32 | NS | < 0.0001 | < 0.0001 | |
Smoking | 0 | 0 | 0 | ||||
Hormonal Diseases | 8 | 16 | 19 | NS | 0.002 | 0.001 | |
Diabetes | 3 | 3 | 6 | NS | NS | NS | |
Liver Diseases | 0 | 2 | 4 | NS | 0.029 | NS | |
Thyroid Diseases | 0 | 25 | 32 | NS | < 0.0001 | < 0.0001 | |
Genetic Diseases | 0 | 1 | 0 | NS | NS | NS | |
Chronic Infection | 0 | 0 | 0 | ||||
Chronic Inflammation | 0 | 0 | 0 | ||||
Heart Problem | 0 | 0 | 0 | ||||
Kidney Problem | 0 | 0 | 0 | ||||
Anxiety | 10 | 7 | 11 | NS | NS | NS |