Skip to main content

Table 1 Sociodemographic, Haematological and Fibrotic indices of the Participants

From: Assessment of the performance of haematological and non-invasive fibrotic indices for the monitoring of chronic HBV infection: a pilot study in a Ghanaian population

Variable

Category

Cases (n = 150) mean (SD)

Controls (N = 150) mean (SD)

P-value

Gender

Male

59 (39.3)

69 (46.0)

0.24

Female

91 (60.7)

81 (54.0)

Age (Yrs.)#

18–36

116 (79.5)

111 (74.0)

0.05

37–53

30 (20.5)

33 (22.0)

54–64

0 (0.0)

6 (4.0)

Hb (12.0–18.0) (g/dl)

 

12.3 (2.1)

12.9 (1.9)

0.01

Total WBC count (4.3–11.5) 109/L

 

5.9 (1.8)

6.8 (3.1)

 < 0.001

Neutrophils (50.0–70.0%)

 

45.9 (13.4)

57.6 (15.3)

 < 0.001

Lymphocytes (20.0–40.0%)

 

44.1 (13.0)

32.8 (14.2)

 < 0.001

Monocytes (3.0–12.0%)

 

5.8 (4.8)

6.9 (2.7)

0.01

Eosinophils (0.5–5.0%)

 

3.2 (3.1)

2.5 (2.8)

0.03

Basophils (0.0–1.0%)

 

1.2 (1.6)

0.3 (0.6)

 < 0.001

Platelets (100–300) × 109/L

 

195 (53)

222 (70)

 < 0.001

Hematocrit (37.0–54.0%)

 

36.7 (6.7)

35.4 (5.9)

0.09

RBC's (3.5–5.5) × 1012/L)

 

4.3 (0.7)

4.2 (0.6)

0.13

MCV (80.0–100.0fL)

 

83.2 (11.1)

83.9 (7.5)

0.47

MCH (27.0–34.0 pg)

 

28.3 (5.5)

30.9 (5.7)

 < 0.001

MCHC (32.0–36.0 g/dL)

 

32.9 (3.2)

36.2 (3.0)

 < 0.001

RDW-CV (11.0–16.0%)

 

15.3 (4.4)

13.4 (1.4)

 < 0.001

RDW-SD (35.0–56.0fL)

 

46.7 (7.8)

42.8 (5.4)

 < 0.001

PDW (9–17)

 

14.5 (3.2)

15.9 (2.3)

 < 0.001

PCT (0.20–0.35%)

 

0.23 (0.07)

0.22 (0.07)

 < 0.001

MPV (8.0–11.5fL)

 

12.2 (4.3)

9.8 (1.3)

 < 0.001

De-Ritis ratio

 

1.350 ± 1.268

1.094 ± 0.410

0.02

FIB-4

 

1.082 ± 1.122

0.867 ± 0.658

0.05

APRI

 

0.431 ± 0.335

0.349 ± 0.268

0.01

  1. Data is presented as mean ± SD
  2. p-values < 0.05 were considered statistically significant
  3. Hb hemoglobin, WBC White Blood Cell, RBC’s Red Blood Cells, MCV Mean Cell Volume, MCH Mean Cell hemoglobin, MCHC Mean Cell hemoglobin Concentration, RDW-CV Red cell Distribution Width -Coefficient of Variation, RDW-SD Red cell Distribution width—Standard Deviation, PDW Platelet Distribution width, PCT Plateletcrit and MPV Mean Platelet Volume, APRI Aspartate aminotransferase-to-platelet ratio index, FIB-4 fibrosis 4 index, RPR RDW-to-platelet ratio
  4. #4 Participants did not provide their ages