Table 3 Comparison of Haematological and Fibrotic indices between the Controls and HBV infected categories
Haematological index | Control (n = 150) | Acute HBV patients (n = 61) mean (SD) | Chronic HBV patients (N = 89) mean (SD) | P-value |
|---|---|---|---|---|
Hb (12.0–18.0) (g/dl) | 12.9 (1.9) | 12.3 (2.1) | 12.2 (2.1) | 0.021 |
Total WBC count (4.3–11.5) 109/L | 6.9 (3.1) | 5.9 (1.8) | 5.8 (1.9) | 0.003 |
Neutrophils (50.0–70.0%) | 57.4 (15.4) | 45.8 (13.5) | 46.1 (13.6) | < 0.001 |
Lymphocytes (20.0–40.0%) | 33.0 (14.2) | 46.1 (13.3) | 42.8 (12.9) | < 0.001 |
Monocytes (3.0–12.0%) | 6.9 (2.7) | 4.6 (2.7) | 6.5 (5.6) | 0.001 |
Eosinophils (0.5–5.0%) | 2.5 (2.8) | 2.5 (1.6) | 3.7 (1.5) | 0.010 |
Basophils (0.0–1.0%) | 0.3 (0.6) | 0.9 (0.7) | 1.4 (1.8) | < 0.001 |
Platelets (100–300) × 109/L | 222 (70) | 192(46) | 188 (58) | 0.002 |
Hematocrit (37.0–54.0%) | 35.4 (5.9) | 37.5 (6.9) | 37.2 (6.2) | 0.076 |
RBC's (3.5–5.5) × 1012/L) | 4.2 (0.6) | 4.3 (0.7) | 4.3 (0.7) | 0.140 |
MCV (80.0–100.0fL) | 83.9 (7.5) | 86.4 (11.7) | 85.7 (10.1) | 0.490 |
MCH (27.0–34.0 pg) | 30.9 (5.7) | 28.3 (5.9) | 28.1 (5.0) | 0.010 |
MCHC (32.0–36.0 g/dL) | 36.2 (3.0) | 32.8 (7.0) | 32.8 (5.2) | 0.026 |
RDW-CV (11.0–16.0%) | 13.4 (1.4) | 13.5 (1.6) | 12.8 (1.3) | < 0.010 |
RDW-SD (35.0–56.0fL) | 42.8 (5.4) | 48.8 (9.1) | 38.7 (7.0) | < 0.010 |
PDW (9–17) | 15.9 (2.3) | 14.7 (3.4) | 14.9 (2.5) | < 0.010 |
PCT (0.20–0.35%) | 0.22 (0.07) | 0.25 (0.10) | 0.26 (0.07) | < 0.001 |
MPV (8.0–11.5fL) | 9.8 (1.3) | 13.2 (7.3) | 12.2 (4.4) | < 0.001 |
De-Ritis ratio | 1.01 ± 0.41 | 1.09 ± 1.27 | 1.35 ± 0.84 | 0.038 |
FIB-4 | 0.87 ± 0.66 | 1.07 ± 1.12 | 1.16 ± 1.03 | 0.032 |
APRI | 0.350 ± 0.27 | 0.39 ± 0.34 | 0.38 ± 0.29 | 0.010 |
RPR | 0.06 ± 0.04 | 0.07 ± 0.05 | 0.08 ± 0.05 | < 0.001 |