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Table 4 Diagnostic performance of biochemical markers for predicting 25(OH) D deficiency among General Population

From: Investigation of serum level relationship of pro-inflammatory and anti-inflammatory cytokines with vitamin D among healthy Ghanaian population

Biomarkers

AUC (95% CI)

Threshold value

Sensitivity

Specificity

PPV

NPV

Kappa

IL-10 (pg/ml)

0.707(0.662–0.753)*

5.59

62.8(56.3–68.9)

71.6(66.8–76.5)

68.9

65.8

0.678

TNF-alpha (pg/ml)

0.849(0.816–0.883)*

6.32

82.6(76.9–87.0)

77.7(72.4–82.1)

78.7

81.7

0.798

IFN-gamma (pg/ml)

0.879(0.847–0.911)*

9.75

81.7(75.9–86.2)

86.2(81.6–89.7)

85.5

82.5

0.842

  1. PPV: positive predictive value; NPV: negative predictive value; CI: confidence interval; AUC: Area under the curve. * indicates significant AUC
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BMC Research Notes

ISSN: 1756-0500

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