Table 1 Damaging nsSNPs from OGT
From: An in-silico analysis of OGT gene association with diabetes mellitus
S/N | rsID | AA Change/position | PROVEAN | PhD-SNPs | SNPs&GO | PolyPhen2 |
|---|---|---|---|---|---|---|
1 | rs766646613 | R627C | -4.677 Deleterious | Disease RI-2 | Neutral | 0.999 probably damaging |
2 | rs131705060 | R117C | -4.194 Deleterious | Disease RI-1 | Disease RI-1 | 0.932 probably damaging |
3 | rs204042438 | P879L | -9.041 Deleterious | Disease RI-6 | Neutral | 0.942 probably damaging |
4 | rs204039392 | P685Q | -7.872 Deleterious | Neutral | Disease RI-4 | 0.994 probably damaging |
5 | rs204042400 | R867C | -5.399 Deleterious | Disease RI- 1 | Neutral | 0.994 probably damaging |
6 | rs204034593 | A380V | -3.790 Deleterious | Neutral | Disease RI-4 | 0.938 probably damaging |
7 | rs766646613 | R627C | -4.677 Deleterious | Disease RI-2 | Neutral | 0.999 probably damaging |
8 | rs2040347448 | M401T | -4.727 Deleterious | Disease RI-2 | Neutral | 0.998 probably damaging |
9 | rs2040347668 | C417Y | -8.596 Deleterious | Neutral | Disease RI-1 | 0.989 probably damaging |
10 | rs2040350890 | D481G | -4.340 Deleterious | Disease 1 | Disease RI-2 | benign |
11 | rs2040368778 | H611N | -5.952 Deleterious | Disease 2 | Neutral | 0.55 probably damaging |
12 | rs2040387073 | P657L | -9.335 Deleterious | Neutral | Disease RI-6 | 0.924 probably damaging |
13 | rs2040191136 | Y112S | -7.489 Deleterious | Neutral | Disease RI-7 | 0.973 probably damaging |
14 | rs2040329106 | Y228H | -2.680 Deleterious | Disease 5 | Disease RI-0 | 0.997 probably damaging |
15 | rs2040334939 | R250C | -6.093 Deleterious | Disease 3 | Disease RI-3 | 1.000 probably damaging |
16 | rs2040341169 | G341V | -7.294 Deleterious | Disease RI-3 | Disease RI-3 | 0.991 probably damaging |
17 | rs2040345810 | L367F | -3.717 Deleterious | Disease 1 | Disease RI-1 | 0.999 probably damaging |
18 | rs2040190682 | R102G | -4.116 Deleterious | Neutral | Disease RI-1 | 0.930 PROBABLY DAMAGING |
19 | rs2040334968 | R250L | -5.405 Deleterious | Disease 2 | Disease RI-0 | 1.000 probably damaging |
20 | rs772525369 | R899C | -6.682 Deleterious | Disease RI-0 | Disease RI-2 | 1.000 probably damaging |
21 | rs1114167891 | R284P | -4.060 Deleterious | Disease 6 | Disease RI-6 | 0.951 probably damaging |
22 | rs1556046834 | G103R | -5.717 Deleterious | Disease 5 | Disease RI-6 | 0.993 probably damaging |
23 | rs1602152230 | N648Y | -7.605 Deleterious | Disease 6 | Disease RI-0 | 0.998 probably damaging |
24 | rs2040405196 | C845S | -7.654 Deleterious | Disease 3 | Disease RI-3 | 0.930 probably damaging |
25 | rs200109331 | N196K | -4.599 Deleterious | Disease 5 | Disease RI-5 | 1.000 probably damaging |