Table 5 Molecular docking results of mutant type OGT against OSMI-1
From: An in-silico analysis of OGT gene association with diabetes mellitus
S/N | Amino acid change | Docking scores | Interacting residues |
|---|---|---|---|
1 | G103R | -4.646 | GLU649, LYS534, ARG338, and ASN621 |
2 | N196K | -5.183 | LYS644, GLY645, and ASN648 |
3 | Y228H | -5.069 | LYS534, ASN621, ALA646, and TYR642 |
4 | R250C | -4.775 | HIS508, LYS852, THR932, PHE878, LYS908, HIS568, and LYS644 |
5 | C845S | -4.571 | GLU649 |
6 | G341V | -5.145 | ASN567, SER594, and LYS644 |
7 | L367F | -5.563 | GLU649, ALA646, TYR642, and LYS534 |