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  1. Copy number variation (CNV) in the range from 2 to 12 per diploid genome is an outstanding feature of the beta-defensin gene (DEFB) cluster on human chromosome 8p23.1 numerously demonstrated by different metho...

    Authors: Stefan Taudien, Klaus Huse, Marco Groth and Matthias Platzer
    Citation: BMC Research Notes 2014 7:93
  2. Campylobacter jejuni is a potent bacterial pathogen culpable for diarrheal disease called campylobacteriosis. It is realized as a major health issue attributable to unavailability of appropriate vaccines and clin...

    Authors: Arun G Ingale and Susumu Goto
    Citation: BMC Research Notes 2014 7:92
  3. A decoction of Crassocephallum vitellinum (Benth.) S. Moore (Asteraceae) is used in Kagera Region to treat peptic ulcers. This study seeks to evaluate an aqueous ethanol extract of aerial parts of the plant for s...

    Authors: Mainen J Moshi, Ramadhani SO Nondo, Emmanuel E Haule, Rogasian LA Mahunnah and Abdul W Kidukuli
    Citation: BMC Research Notes 2014 7:91
  4. Psychiatric manifestations have been noted in patients with low serum vitamin B12 levels even in the absence of other neurologic and/or haematologic abnormalities. There is no literature on low serum B12 prevalen...

    Authors: Michael Ssonko, Henry Ddungu and Seggane Musisi
    Citation: BMC Research Notes 2014 7:90
  5. Posterior reversible encephalopathy syndrome is a presentation which is diagnosed clinico-radiologically. The primary aetiological processes leading to posterior reversible encephalopathy syndrome are many, wh...

    Authors: Mitrakrishnan Rayno Navinan, Chandrika Jayakanthi Subasinghe, Thambyaiah Kandeepan and Aruna Kulatunga
    Citation: BMC Research Notes 2014 7:89
  6. School age children are one of the groups at high risk for intestinal parasitic infections especially in developing countries like Ethiopia as the supply of good quality drinking water and latrine coverage are...

    Authors: Biniam Mathewos, Abebe Alemu, Desalegn Woldeyohannes, Agersew Alemu, Zelalem Addis, Moges Tiruneh, Mulugeta Aimero and Afework Kassu
    Citation: BMC Research Notes 2014 7:88
  7. Melamine was recently identified as a risk factor for renal calculi following the milk powder contamination in China. However, the long-term natural history of melamine exposure and its renal effects remain un...

    Authors: Takahiro Yasui, Takahiro Kobayashi, Atsushi Okada, Shuzo Hamamoto, Masahito Hirose, Kentaro Mizuno, Yasue Kubota, Yukihiro Umemoto, Noriyasu Kawai, Keiichi Tozawa, Bing Gao and Kenjiro Kohri
    Citation: BMC Research Notes 2014 7:87
  8. No previous studies have examined the effect of intensive exercise in systemic sclerosis patients with pulmonary impairment. The objective of this study was to examine the effect of an eight-week intensive aer...

    Authors: Helene Alexanderson, Jenny Bergegård, Lena Björnådal and Annica Nordin
    Citation: BMC Research Notes 2014 7:86
  9. Conservative methods for weight loss are usually disappointing. Therefore, surgeries such as Laparoscopic Sleeve Gastrectomy (LSG) should be considered. We aimed to evaluate the outcomes (body mass index; BMI)...

    Authors: Hamzeh Al Zabadi, Ahmad Daqour, Abdullah Hawari and Jihad Hasouni
    Citation: BMC Research Notes 2014 7:85
  10. Zinc is essential for the activities of pancreatic β-cells, especially insulin storage and secretion. Insulin secretion leads to co-release of zinc which contributes to the paracrine communication in the pancr...

    Authors: Sanne Bjørn Nygaard, Agnete Larsen, Astrid Knuhtsen, Jørgen Rungby and Kamille Smidt
    Citation: BMC Research Notes 2014 7:84
  11. Sequence determines the three-dimensional structure of RNAs, and thereby plays an important role in carrying out various biological functions. RNA duplexes containing Watson-Crick (WC) basepairs, interspersed ...

    Authors: Senthilkumar Kailasam, Dhananjay Bhattacharyya and Manju Bansal
    Citation: BMC Research Notes 2014 7:83
  12. The electrical impedance tomography (EIT)-based global inhomogeneity (GI) index was introduced to quantify tidal volume distribution within the lung. Up to now, the GI index was evaluated for plausibility but ...

    Authors: Zhanqi Zhao, Sven Pulletz, Inéz Frerichs, Ullrich Müller-Lisse and Knut Möller
    Citation: BMC Research Notes 2014 7:82
  13. Homeless shelters are identified as places where humans are at high risk of acquiring respiratory disease. We previously reported the prevalence of the main respiratory diseases affecting a population of homel...

    Authors: Simon-djamel Thiberville, Nicolas Salez, Samir Benkouiten, Sekene Badiaga, Remi Charrel and Philippe Brouqui
    Citation: BMC Research Notes 2014 7:81
  14. As biological disciplines extend into the ‘big data’ world, they will need a names-based infrastructure to index and interconnect distributed data. The infrastructure must have access to all names of all organ...

    Authors: David J Patterson, Willi Egloff, Donat Agosti, David Eades, Nico Franz, Gregor Hagedorn, Jonathan A Rees and David P Remsen
    Citation: BMC Research Notes 2014 7:79
  15. Hemodialysis is essential for the survival of patients suffering from chronic renal failure. However, in diabetics the incidence of dry eye disease is higher than in non-diabetic individuals. Accordingly, we eval...

    Authors: Motoko Nakata, Yuka Okada, Hirotsugu Kobata, Takashi Shigematsu, Peter S Reinach, Katsuo Tomoyose and Shizuya Saika
    Citation: BMC Research Notes 2014 7:78
  16. Gracilaria tenuistipitata is an agarophyte with substantial economic potential because of its high growth rate and tolerance to a wide range of environment factors. This red seaweed is intensively cultured in Chi...

    Authors: Sze-Looi Song, Phaik-Eem Lim, Siew-Moi Phang, Weng-Wah Lee, Dang Diem Hong and Anchana Prathep
    Citation: BMC Research Notes 2014 7:77
  17. Visceral leishmaniasis (VL) causes considerable morbidity and mortality in Ethiopia. Data on the prevalence and associated risk factors on malnutrition among VL patients in Ethiopia are scarce. This study aime...

    Authors: Bewketu Mengesha, Mengistu Endris, Yegnasew Takele, Kalehiwot Mekonnen, Takele Tadesse, Amsalu Feleke and Ermias Diro
    Citation: BMC Research Notes 2014 7:75
  18. Intubation of patients with laryngeal granulomas on the vocal folds are sometimes difficult to manage because of potential airway obstruction. Laryngeal granulomas usually have flexible stalks where they attac...

    Authors: Junko Nakahira, Toshiyuki Sawai, Sayuri Matsunami and Toshiaki Minami
    Citation: BMC Research Notes 2014 7:74
  19. The Antarctic krill, Euphausia superba is a pelagic crustacean, abundant in high-density swarms (10 000 – 30 000 ind/m2) with a circumpolar distribution and a key role in the food web of the Southern Ocean. Only ...

    Authors: Rui Candeias, Sara Teixeira, Carlos M Duarte and Gareth A Pearson
    Citation: BMC Research Notes 2014 7:73
  20. Type 1 diabetes is one of the most frequent long-term endocrine childhood disorders and the Swedish National Diabetes Register for children states that adolescents (12–18 years) constitute the most vulnerable ...

    Authors: Helena Wigert and Ewa Wikström
    Citation: BMC Research Notes 2014 7:72
  21. Good communication is an important prerequisite for equal treatment in a healthcare encounter. One way to overcome language barriers when patients and healthcare staff do not share the same language is to use ...

    Authors: Emina Hadziabdic, Björn Albin and Katarina Hjelm
    Citation: BMC Research Notes 2014 7:71
  22. It has been reported that repeated intravenous injections of a relatively large amount of Leishmania amazonensis amastigote extract (La E) in BALB/c mice exacerbates the infection of these mice by Leishmania braz...

    Authors: Cintia F de Araújo, Virgínia MG Silva, Andre Cronemberger-Andrade, Luciana S Aragão-França, Viviane CJ Rocha, Priscila SL Santos and Lain Pontes-de-Carvalho
    Citation: BMC Research Notes 2014 7:70
  23. One of the concerns of assembling de novo transcriptomes is determining the amount of read sequences required to ensure a comprehensive coverage of genes expressed in a particular sample. In this report, we descr...

    Authors: Keng-See Chow, Ahmad-Kamal Ghazali, Chee-Choong Hoh and Zainorlina Mohd-Zainuddin
    Citation: BMC Research Notes 2014 7:69
  24. The field of population genetics use the genetic composition of populations to study the effects of ecological and evolutionary factors, including selection, genetic drift, mating structure, and migration. Unt...

    Authors: Ketil Malde
    Citation: BMC Research Notes 2014 7:68
  25. To study the association between organizational context and research utilization in German residential long term care (LTC), we translated three Canadian assessment instruments: the Alberta Context Tool (ACT),...

    Authors: Matthias Hoben, Marion Bär, Cornelia Mahler, Sarah Berger, Janet E Squires, Carole A Estabrooks, Andreas Kruse and Johann Behrens
    Citation: BMC Research Notes 2014 7:67
  26. This paper reports on an Australian experience of co-locating a range of different primary health services into one building, with the aim of providing integrated services. It discusses some of the early chall...

    Authors: Sharon Lawn, Andrea Lloyd, Alison King, Linda Sweet and Lyn Gum
    Citation: BMC Research Notes 2014 7:66
  27. Little is known about the clinical features and treatment of Chinese patients with Parkinson disease (PD).

    Authors: Zhen-Xin Zhang, Honglei Chen, Sheng-Di Chen, Ming Shao, Sheng-Gang Sun, Qiu-Min Qu, Bao-Rong Zhang, Yi-Ming Liu, Qun Xu, Xia Wan, Ling Li, Hong-Bo Wen, Xia Chen, Hai-Bo Chen, Zhen-Guo Liu, Jian Wang…
    Citation: BMC Research Notes 2014 7:65
  28. Prostate-specific antigen (PSA) is a widely used specific tumor marker for prostate cancer. We experienced a case of metastatic prostate cancer that was difficult to detect by repeat prostate biopsy despite a ...

    Authors: Hiromichi Iwamura, Shingo Hatakeyama, Yoshimi Tanaka, Toshikazu Tanaka, Noriko Tokui, Hayato Yamamoto, Atsushi Imai, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Kazuaki Yoshikawa and Chikara Ohyama
    Citation: BMC Research Notes 2014 7:64
  29. Plasminogen (Pg), the precursor of the proteolytic and fibrinolytic enzyme of blood, is converted to the active enzyme plasmin (Pm) by different plasminogen activators (tissue plasminogen activators and urokin...

    Authors: Selvaraj Muthukrishnan, Munish Puri and Christophe Lefevre
    Citation: BMC Research Notes 2014 7:63
  30. In order to provide gene expression profiles of different cell types, the primary step is to isolate the specific cells of interest via laser capture microdissection (LCM), followed by extraction of good quali...

    Authors: Jie Yin Yee, Lie Michael George Limenta, Keith Rogers, Susan Mary Rogers, Vanessa SY Tay and Edmund JD Lee
    Citation: BMC Research Notes 2014 7:62
  31. Finding genes that share similar expression patterns across samples is an important question that is frequently asked in high-throughput microarray studies. Traditional clustering algorithms such as K-means cl...

    Authors: Li-Xuan Qin, Linda Breeden and Steven G Self
    Citation: BMC Research Notes 2014 7:60
  32. Autoimmune thrombocytopenic purpura is an immunological disorder characterized by increased platelet destruction due to presence of anti-platelet autoantibodies. Hepatitis C virus infection, which is one of th...

    Authors: Rita Lebano, Valerio Rosato, Mario Masarone, Marco Romano and Marcello Persico
    Citation: BMC Research Notes 2014 7:59
  33. The EPSPS, EC 2.5.1.19 (5-enolpyruvylshikimate −3-phosphate synthase) is considered as one of the crucial enzyme in the shikimate pathway for the biosynthesis of essential aromatic amino acids and secondary me...

    Authors: Bharti Garg, Neha Vaid and Narendra Tuteja
    Citation: BMC Research Notes 2014 7:58
  34. In the general population visual-spatial ability is better in males, due to the influence of biological and socio-cultural factors. We know that sport activity improves motor skills. The aim of this work is to...

    Authors: Angela Notarnicola, Giuseppe Maccagnano, Vito Pesce, Silvio Tafuri, Grazia Novielli and Biagio Moretti
    Citation: BMC Research Notes 2014 7:57
  35. The prevalence of chronic hepatitis B and C was evaluated some twenty years ago among specific populations in Guadeloupe. The present study was designed to update these data and determine epidemiological featu...

    Authors: Moana Gelu-Simeon, Valérie Pillas, Jacqueline Deloumeaux, Hélène Delacroix-Maillard, Georgette Saint-Georges, Léonardo Do Amaral, Marius Borel, Marc Laurent, Emmanuel Gordien and Eric Saillard
    Citation: BMC Research Notes 2014 7:55
  36. Pegloticase is approved in the US for treatment of refractory chronic gout. Since chronic kidney disease (CKD) is common in these patients, we conducted a post-hoc analysis of 2 replicate phase 3 trials and th...

    Authors: Robert A Yood, Faith D Ottery, William Irish and Marsha Wolfson
    Citation: BMC Research Notes 2014 7:54
  37. Quality of life (QOL) and its measurement in cancer patients is becoming increasingly important. Breast cancer diagnosis and treatment are often associated with psychological distress and reduced QoL. In Arabi...

    Authors: Samira El Fakir, Naima Abda, Karima Bendahhou, Ahmed Zidouh, Maria Bennani, Hassan Errihani, Abdelatif Benider, Rachid Bekkali and Chakib Nejjari
    Citation: BMC Research Notes 2014 7:53
  38. Ensuring that no baby is born with HIV is an essential step towards achieving an AIDS-free generation. To achieve this, strategies that decouple links between childbirth and HIV transmission are necessary. Tra...

    Authors: Erastus K Ngemu, Christopher Khayeka-Wandabwa, Eliningaya J Kweka, Joseph K Choge, Edward Anino and Elijah Oyoo-Okoth
    Citation: BMC Research Notes 2014 7:52

    The Retraction Note to this article has been published in BMC Research Notes 2014 7:868

  39. There are challenges, when extracting bacterial DNA from specimens for molecular diagnostics, since fecal samples also contain DNA from human cells and many different substances derived from food, cell residue...

    Authors: Hengameh Mirsepasi, Søren Persson, Carsten Struve, Lee O B Andersen, Andreas M Petersen and Karen A Krogfelt
    Citation: BMC Research Notes 2014 7:50
  40. Free radicals-induced neurodegeneration is one of the many causes of Parkinson’s disease (PD). This study investigated the neuroprotective effects of flavonol isoquercitrin against toxicity induced by 6-hydrox...

    Authors: Kasthuri Bai Magalingam, Ammu Radhakrishnan and Nagaraja Haleagrahara
    Citation: BMC Research Notes 2014 7:49
  41. The multifactorial control of diabetes relies on interventions that provide patients with the best knowledge and resources available. The objective of this research was to analyze the clinical characteristics ...

    Authors: María Orosia Lucha-López, Ana Carmen Lucha-López, Concepción Vidal-Peracho, José Miguel Tricás-Moreno, Elena Estébanez-De Miguel, Carlos Salavera-Bordás and Cesar Hidalgo-García
    Citation: BMC Research Notes 2014 7:48
  42. To understand the clinical characteristics and the diagnostic procedures in pediatric patients with eosinophilic esophagitis and to evaluate the sensitivity of the patients to food and inhalant allergens. A cr...

    Authors: Erica Rodrigues Mariano de Almeida Rezende, Cristina Palmer Barros, Leandro Hideki Ynoue, Amanda Torido Santos, Rogerio Melo Costa Pinto and Gesmar Rodrigues Silva Segundo
    Citation: BMC Research Notes 2014 7:47
  43. Mortalities in the health care set up are prevalent, and causes are multifactorial with variations from area to area and also from ward to ward in the same health care set up. Analysis of mortalities and its c...

    Authors: Asrat Agalu Abejew, Alemneh Smieneh Tamir and Mirkuzie Woldie Kerie
    Citation: BMC Research Notes 2014 7:46
  44. Tuberculosis is still the leading cause of illness in the world which accounted for 2.5% of the global burden of disease, and 25% of all avoidable deaths in developing countries. The aim of study was to assess...

    Authors: Solomon Sisay, Belete Mengistu, Woldaregay Erku and Desalegn Woldeyohannes
    Citation: BMC Research Notes 2014 7:44
  45. The rapid development of next generation sequencing technologies, including the recently introduced benchtop sequencers, made sequencing affordable for smaller research institutions. A widely applied method to...

    Authors: Andreas Dander, Stephan Pabinger, Michael Sperk, Maria Fischer, Gernot Stocker and Zlatko Trajanoski
    Citation: BMC Research Notes 2014 7:43

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