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  1. Hepatitis B (HB) and C (HC) are two severe viral infectious diseases with a deleterious impact on global health. This study aimed to evaluate the prevalence of HB and HC in the Prospective Epidemiological Rese...

    Authors: Fariborz Mansour-Ghanaei, Farahnaz Joukar, Mohammadreza Naghipour, Soheil Hassanipour, Sara Yeganeh, Masood Sepehrimanesh and Mohammad Fathalipour
    Citation: BMC Research Notes 2021 14:59
  2. This study was designed to discover the dissemination of virulence genes in Methicillin-resistant Staphylococcus aureus from clinical, community and environmental settings.

    Authors: Deepshikha Bhowmik, Shiela Chetri, Bhaskar Jyoti Das, Debadatta Dhar Chanda and Amitabha Bhattacharjee
    Citation: BMC Research Notes 2021 14:58
  3. Human papillomavirus (HPV) gained momentum as a potential etiological factor for many types of cancers. Therefore, the aim of this study was to assess the prevalence of HPV-16 infection among Sudanese patients di...

    Authors: Fatima E. Mohamed, Leena N. Aldayem, Maisa A. Hemaida, Omayma Siddig, Zeinab H. Osman, Irene R. Shafig, Mohamed A. M. Salih, Mohamed S. Muneer, Rowa Hassan, Eiman Siddig Ahmed, Lamis Ahmed Hassan, Osama El Hadi Bakheet, Ali M. M. Edris, Ayman Ahmed, Nouh S. Mohamed and Emmanuel E. Siddig
    Citation: BMC Research Notes 2021 14:56
  4. Neonatal mortality is a global public health problem, and the efforts to reduce child mortality is one of the goals of the 2030 Agenda for Sustainable Development, launched in 2015 by the United Nations. The a...

    Authors: Lais Baroni, Rebecca Salles, Samella Salles, Marcel Pedroso, Jefferson Lima, Igor Morais, Lucas Carraro, Raphael de Freitas Saldanha, Carlos Sousa, Carlos Cardoso, Balthazar Paixño, Sérgio Cruz, Eduardo Ogasawara, Patrícia de Morais Mello Boccolini and Cristiano Siqueira Boccolini
    Citation: BMC Research Notes 2021 14:55
  5. Altitude integrates changes in environmental conditions that determine shifts in vegetation, including temperature, precipitation, solar radiation and edaphogenetic processes. In turn, vegetation alters soil b...

    Authors: Alexia Stokes, Guillermo Angeles, Fabien Anthelme, Eduardo Aranda-Delgado, Isabelle Barois, Manon Bounous, Nereyda Cruz-Maldonado, Thibaud Decaëns, Stéphane Fourtier, Grégoire T. Freschet, Quentin Gabriac, Daniel Hernández-Cáceres, Leonor Jiménez, Jing Ma, Zhun Mao, Beatriz Eugenia Marín-Castro…
    Citation: BMC Research Notes 2021 14:54
  6. Sequestosome 1 (p62/SQSTM1) is a multifunctional scaffold/adaptor protein encoded by the p62/SQSTM1 gene with function in cellular homeostasis. Mutations in the p62/SQSTM1 gene have been known to be associated wi...

    Authors: Emily P. Hurley and Brian E. Staveley
    Citation: BMC Research Notes 2021 14:53
  7. Differential alterations in gut microbiota and chronic low-grade inflammation play a critical role in the development of Type 2 diabetes (T2D). Here we aimed to investigate if dysbiosis of inflammation and ant...

    Authors: Prasanna Kulkarni, Poornima Devkumar and Indranil Chattopadhyay
    Citation: BMC Research Notes 2021 14:52
  8. Adults with Prader–Willi syndrome (PWS) require less energy intake to maintain body weight than the general adult population. This, combined with their altered gastrointestinal transit time, may impact microbi...

    Authors: Wendy J. Dahl, Jérémie Auger, Zainab Alyousif, Jennifer L. Miller and Thomas A. Tompkins
    Citation: BMC Research Notes 2021 14:51
  9. Toxoplasma gondii (T. gondii), an obligate intracellular apicomplexan parasite, could affect numerous warm-blooded animals, such as humans. Calcium-dependent protein kinases (CDPKs) are essential Ca2+ signaling m...

    Authors: Masoud Foroutan, Ali Dalir Ghaffari, Shahrzad Soltani, Hamidreza Majidiani, Ali Taghipour and Mohamad Sabaghan
    Citation: BMC Research Notes 2021 14:50
  10. Coronary artery disease (CAD) is an important cause of mortality and morbidity, therefore, recognizing its severity and related factors is important. This study was performed to evaluate the association betwee...

    Authors: Iman Mohseni, Afshin Shiri and Simindokht Mojahedin
    Citation: BMC Research Notes 2021 14:49
  11. Anxiety is reportedly prevalent in older adults with dementia living in care homes and, within this population, is most often assessed through caregiver reports. Heart rate variability (HRV) is a physiological...

    Authors: Milena A. Quinci and Arlene J. Astell
    Citation: BMC Research Notes 2021 14:48
  12. Trial registries were set up to improve transparency, remove duplication, improve awareness and avoid waste. Many trials never reach the point of patient enrolment due to a myriad of reasons. The aim of this s...

    Authors: Akke Vellinga, Kathryn Lambe, Paul O’Connor and Angela O’Dea
    Citation: BMC Research Notes 2021 14:47
  13. Toxoplasmosis, caused by Toxoplasma gondii, infects humans by consuming infected raw or undercooked meat and foods harboring mature oocysts. In this study, we assessed the prevalence of T. gondii in sheep and goa...

    Authors: Mojtaba Bahreh, Bahador Hajimohammadi and Gilda Eslami
    Citation: BMC Research Notes 2021 14:46
  14. Kazakhstan is a Central Asian crossroad of European and Asian populations situated along the way of the Great Silk Way. The territory of Kazakhstan has historically been inhabited by nomadic tribes and today i...

    Authors: Ulykbek Kairov, Askhat Molkenov, Saule Rakhimova, Ulan Kozhamkulov, Aigul Sharip, Daniyar Karabayev, Asset Daniyarov, Joseph H.Lee, Joseph D.Terwilliger, Ainur Akilzhanova and Zhaxybay Zhumadilov
    Citation: BMC Research Notes 2021 14:45
  15. In this 7-day pilot study we randomized healthy, normal-weight men and women to either a dietary intervention with methionine and cysteine restriction enriched in PUFA (Met/Cyslow + PUFA, n = 7) or with high cont...

    Authors: Thomas Olsen, Bente Øvrebø, Cheryl Turner, Nasser E. Bastani, Helga Refsum and Kathrine J. Vinknes
    Citation: BMC Research Notes 2021 14:43
  16. Currently the majority of non-culturable microbes in sea water are yet to be discovered, Nanopore offers a solution to overcome the challenging tasks to identify the genomes and complex composition of oceanic ...

    Authors: M. Liem, T. Regensburg-Tuïnk, C. Henkel, H. Jansen and H. Spaink
    Citation: BMC Research Notes 2021 14:42
  17. Contaminated poultry feeds can be a major source of E. coli and Salmonella infections in poultry. This study aimed at determining microbial load, prevalence and antimicrobial resistance profiles of Salmonella sp....

    Authors: Dorica Gakii Ngai, Anthony Kebira Nyamache and Omwoyo Ombori
    Citation: BMC Research Notes 2021 14:41
  18. Annually, 1.2 million humans are stung by scorpions and severely affected by their venom. Some of the scorpion species of medical importance have a similar morphology to species with low toxicity. To establish...

    Authors: Parisa Soltan-Alinejad, Javad Rafinejad, Farrokh Dabiri, Piero Onorati, Olle Terenius and Ali Reza Chavshin
    Citation: BMC Research Notes 2021 14:40
  19. Floral structures may be warmer than their environment, and can show thermal patterning, where individual floral structures show different temperatures across their surface. Pollinators can differentiate betwe...

    Authors: Sean A. Rands and Michael J. M. Harrap
    Citation: BMC Research Notes 2021 14:39
  20. Ficolin-3 is one of the innate immunity molecules that was thought to play a pivotal role in Streptococcus pyogenes autoimmunity and its complications; rheumatic fever (RF) and rheumatic heart disease (RHD). We a...

    Authors: Maher H. Gomaa, Emad Gamil Khidr, Ahmed Elshafei, Hala S. Hamza, Aya M. Fattouh, Ahmed A. El-Husseiny, Ahmed Aglan and Mahmoud Gomaa Eldeib
    Citation: BMC Research Notes 2021 14:36
  21. Neglect after stroke is a disabling disorder and its rehabilitation is a major challenge. Transcranial direct current stimulation (tDCS) seems to be a promising adjuvant technique to improve standard care negl...

    Authors: Anna Gorsler, Ulrike Grittner, Nadine Külzow and Torsten Rackoll
    Citation: BMC Research Notes 2021 14:35
  22. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Kahsay Gebrehiwet, Fitsum Abrha, Hailay Gebreyesus and Mebrahtu Teweldemedhin
    Citation: BMC Research Notes 2021 14:34

    The original article was published in BMC Research Notes 2020 13:182

  23. To examine gender and socioeconomic differences in adolescents’ reasons for not smoking cigarettes using self-reported data from Danish 14-year-olds (N = 1,559) collected in 2018. χ2-tests were used to assess whe...

    Authors: Simone Gad Kjeld, Stine Glenstrup and Lotus Sofie Bast
    Citation: BMC Research Notes 2021 14:33
  24. Vertical transmission from SARS CoV-2-infected women is uncommon and coronavirus has not been detected in amniotic fluid. Human amniotic products have a broad immune-mediating profile. Observing that many COVI...

    Authors: Craig H. Selzman, Joseph E. Tonna, Jan Pierce, Camila Vargas, Chloe Skidmore, Giavonni Lewis, Nathan D. Hatton and John D. Phillips
    Citation: BMC Research Notes 2021 14:32
  25. Matrix metalloproteinases (MMPs) are important regulators of vascular and uterine remodeling. They exhibit proteolytic activity implicating the efficiency of trophoblast invasion to the uterine wall involving ...

    Authors: Ritva Nissi, Markku Santala and Anne Talvensaari-Mattila
    Citation: BMC Research Notes 2021 14:31
  26. Receiving a diagnosis of dementia is life-changing for the individual and their companion. The aim of the study was to explore the feasibility of collecting salivary cortisol from patients who are informed if ...

    Authors: H. Pavlickova, A. E. Russell, S. Lightman and R. McCabe
    Citation: BMC Research Notes 2021 14:30
  27. To describe frequency and clinical characteristics of MAYV infection in Piura, as well as the association of this pathogen with DENV.

    Authors: Miguel Angel Aguilar-Luis, Juana del Valle-Mendoza, Isabel Sandoval, Wilmer Silva-Caso, Fernando Mazulis, Hugo Carrillo-Ng, Yordi Tarazona-Castro, Johanna Martins-Luna, Ronald Aquino-Ortega, Isaac Peña-Tuesta, Angela Cornejo-Tapia and Luis J. del Valle
    Citation: BMC Research Notes 2021 14:29
  28. The objectives of this work are to isolate, develop, and characterize polymorphic microsatellite markers for use in Greenland sharks (Somniosus microcephalus).

    Authors: Meaghan A. Swintek and Ryan P. Walter
    Citation: BMC Research Notes 2021 14:28
  29. Combinations of pharmacological agents are essential for disease control and prevention, offering many advantages over monotherapies, with one of these being drug synergy. The state-of-the-art method to profil...

    Authors: Petri Mäkelä, Si Min Zhang and Sean G. Rudd
    Citation: BMC Research Notes 2021 14:27
  30. Procalcitonin (PCT) has received much attention as a serum marker for bacterial infection. Elevated serum PCT is occasionally seen in severe trauma, heatstroke, and neoplastic diseases, including lung cancer w...

    Authors: Masamichi Itoga, Hisashi Tanaka, Kageaki Taima, Yoshiko Ishioka, Hiroaki Sakamoto, Shingo Takanashi, Akira Kurose and Sadatomo Tasaka
    Citation: BMC Research Notes 2021 14:25
  31. The purpose of this data set is to capture the complete diurnal (i.e., daily) transcriptome of fully expanded third leaves from the C4 panacoid grasses sorghum (Sorghum bicolor), maize (Zea mays), and foxtail mil...

    Authors: Xianjun Lai, Claire Bendix, Yang Zhang, James C. Schnable and Frank G. Harmon
    Citation: BMC Research Notes 2021 14:24
  32. Proper characterization of hydatid cyst fluid (HCF) is useful for diagnostic and follow up purposes of cystic echinococcosis/hydatidosis, which is an important zoonotic disease. In this regard, proteomics meth...

    Authors: Bahareh Sedaghat, Homa Hajjaran, Fatemeh Sadat Sadjjadi, Soudabeh Heidari and Seyed Mahmoud Sadjjadi
    Citation: BMC Research Notes 2021 14:22
  33. In chronic lymphocytic leukemia (CLL), lack of expression or dysregulation of some special miRs disrupts apoptosis of malignant cells; thereby miR expression can enhance cell proliferation, disease progression...

    Authors: Nader Davari, Fatemeh Ahmadpour, Ali Asghar Kiani, Mozhgan Azadpour and Zari Tahannejad Asadi
    Citation: BMC Research Notes 2021 14:21
  34. We aimed to characterize the effects of prone positioning on respiratory mechanics and oxygenation in invasively ventilated patients with SARS-CoV-2 ARDS.

    Authors: Jennifer Clarke, Pierce Geoghegan, Natalie McEvoy, Maria Boylan, Orna Ní Choileáin, Martin Mulligan, Grace Hogan, Aoife Keogh, Oliver J. McElvaney, Oisín F. McElvaney, John Bourke, Bairbre McNicholas, John G. Laffey, Noel G. McElvaney and Gerard F. Curley
    Citation: BMC Research Notes 2021 14:20
  35. Resveratrol (RSV) is a multitarget drug that has demonstrated activity against Toxoplasma gondii in macrophage and human foreskin fibroblast (HFF) cell line infection models. However, the mechanism of action of R...

    Authors: Susana M. Contreras, Agustina Ganuza, María M. Corvi and Sergio O. Angel
    Citation: BMC Research Notes 2021 14:19
  36. Calcitonin receptor-like receptor (CRLR) regulates vasoconstriction and dilatation; the expression increases during hypoxia via activation of hypoxia response element (HRE) in CRLR gene promoter region. Varian...

    Authors: Herlambang, Amelia Dwi Fitri, Ahmad Syauqy, Yuwono, Anggelia Puspasari, Rina Nofri Enis and Ahmad Faried
    Citation: BMC Research Notes 2021 14:17
  37. Advancing social purpose in organizations is usually studied from the macro perspective, i.e., how it benefits organizational business goals or society more broadly. In this paper, we focus on social purpose f...

    Authors: Malwina Puchalska-Kamińska, Agnieszka Łądka-Barańska and Marta Roczniewska
    Citation: BMC Research Notes 2021 14:16
  38. Standard rodent sepsis models as cecal ligation and puncture models (CLP) or cecal ligation and incision models (CLI) are frequently not suited experiments, mainly because they lack surgical repair, and they a...

    Authors: Julia M. Utiger, Michael Glas, Anja Levis, Josef Prazak and Matthias Haenggi
    Citation: BMC Research Notes 2021 14:14
  39. Validation of a test method is critical for confirming that the test can generate accurate and precise data. Although commercial biochemical test kits exist there are no specific and validated commercial clini...

    Authors: Yoseph Cherinet Megerssa, Fikru Regassa Gari and Fanos Tadesse Woldemariyam
    Citation: BMC Research Notes 2021 14:13
  40. The current study aimed to investigate the ABO and rhesus (Rh) blood group frequency in the people of District Faisalabad and Sheikhupura, Punjab Province, Pakistan. The retrospective study was conducted on mo...

    Authors: Ali Sabir, Arslan Iftikhar, Muhammad Umar Ijaz, Ghulam Hussain, Azhar Rasul, Rana Khalid Iqbal, Faiqa Sajid and Haseeb Anwar
    Citation: BMC Research Notes 2021 14:12
  41. Impaired swallowing is a primary medical concern in head and neck cancer (HNC) patients. Swallowing therapy and supportive care to relieve swallowing problems among HNC patients are recommended. However, no data ...

    Authors: Tseganesh Asefa Yifru, Sezer Kisa, Negalign Getahun Dinegde and Niguse Tadele Atnafu
    Citation: BMC Research Notes 2021 14:11
  42. Pain is one of the most ignored clinical symptoms in resource limited country such as Ethiopia. Trigeminal neuralgia (TN) is one of the most painful medical illnesses known to human. Very little was reported a...

    Authors: Biniyam A. Ayele, Yared Zenebe Zewde, Mikyas Tilahun Degefa and Abenet Tafesse Mengesha
    Citation: BMC Research Notes 2021 14:9

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