WTCCC: Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature. 2007, 447 (7145): 661-678. 10.1038/nature05911.
Article
Google Scholar
Benjamini Y, Hochberg Y: Controlling the false discovery rate: A practical and powerful approach to multiple testing. J R Stat Soc B. 1995, 57: 289-300.
Google Scholar
Storey JD, Tibshirani R: Statistical significance for genomewide studies. Proc Natl Acad Sci USA. 2003, 100 (16): 9440-9445. 10.1073/pnas.1530509100.
Article
CAS
PubMed Central
PubMed
Google Scholar
Holm S: A simple sequentially rejective multiple test procedure. Scand J Statist. 1979, 6: 65-70.
Google Scholar
Genovese C, Roeder K, Wasserman L: False discovery control with P-value weighting. Biometrika. 2006, 93: 509-524. 10.1093/biomet/93.3.509.
Article
Google Scholar
Roeder K, Bacanu SA, Wasserman L, Devlin B: Using linkage genome scans to improve power of association in genome scans. Am J Hum Genet. 2006, 78 (2): 243-252. 10.1086/500026.
Article
CAS
PubMed Central
PubMed
Google Scholar
Sun L, Craiu RV, Paterson AD, Bull SB: Stratified false discovery control for large-scale hypothesis testing with application to genome-wide association studies. Genet Epidemiol. 2006, 30 (6): 519-530. 10.1002/gepi.20164.
Article
PubMed
Google Scholar
Li C, Li M, Lange EM, Watanabe RM: Prioritized subset analysis: improving power in genome-wide association studies. Hum Hered. 2008, 65 (3): 129-141. 10.1159/000109730.
Article
PubMed
Google Scholar
Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, Haynes C, Henning AK, SanGiovanni JP, Mane SM, Mayne ST: Complement factor H polymorphism in age-related macular degeneration. Science. 2005, 308 (5720): 385-389. 10.1126/science.1109557.
Article
CAS
PubMed Central
PubMed
Google Scholar
Abecasis GR, Yashar BM, Zhao Y, Ghiasvand NM, Zareparsi S, Branham KE, Reddick AC, Trager EH, Yoshida S, Bahling J: Age-related macular degeneration: a high-resolution genome scan for susceptibility loci in a population enriched for late-stage disease. Am J Hum Genet. 2004, 74 (3): 482-494. 10.1086/382786.
Article
CAS
PubMed Central
PubMed
Google Scholar
Iyengar SK, Song D, Klein BE, Klein R, Schick JH, Humphrey J, Millard C, Liptak R, Russo K, Jun G: Dissection of genomewide-scan data in extended families reveals a major locus and oligogenic susceptibility for age-related macular degeneration. Am J Hum Genet. 2004, 74 (1): 20-39. 10.1086/380912.
Article
CAS
PubMed Central
PubMed
Google Scholar
Klein ML, Schultz DW, Edwards A, Matise TC, Rust K, Berselli CB, Trzupek K, Weleber RG, Ott J, Wirtz MK: Age-related macular degeneration. Clinical features in a large family and linkage to chromosome 1q. Arch Ophthalmol. 1998, 116 (8): 1082-1088.
Article
CAS
PubMed
Google Scholar
Majewski J, Schultz DW, Weleber RG, Schain MB, Edwards AO, Matise TC, Acott TS, Ott J, Klein ML: Age-related macular degeneration--a genome scan in extended families. Am J Hum Genet. 2003, 73 (3): 540-550. 10.1086/377701.
Article
CAS
PubMed Central
PubMed
Google Scholar
Seddon JM, Santangelo SL, Book K, Chong S, Cote J: A genomewide scan for age-related macular degeneration provides evidence for linkage to several chromosomal regions. Am J Hum Genet. 2003, 73 (4): 780-790. 10.1086/378505.
Article
CAS
PubMed Central
PubMed
Google Scholar
Weeks DE, Conley YP, Tsai HJ, Mah TS, Schmidt S, Postel EA, Agarwal A, Haines JL, Pericak-Vance MA, Rosenfeld PJ: Age-related maculopathy: a genomewide scan with continued evidence of susceptibility loci within the 1q31, 10q26, and 17q25 regions. Am J Hum Genet. 2004, 75 (2): 174-189. 10.1086/422476.
Article
CAS
PubMed Central
PubMed
Google Scholar
Jun G, Klein BE, Klein R, Fox K, Millard C, Capriotti J, Russo K, Lee KE, Elston RC, Iyengar SK: Genome-wide analyses demonstrate novel loci that predispose to drusen formation. Invest Ophthalmol Vis Sci. 2005, 46 (9): 3081-3088. 10.1167/iovs.04-1360.
Article
PubMed
Google Scholar
Scholl HP, Fleckenstein M, Charbel Issa P, Keilhauer C, Holz FG, Weber BH: An update on the genetics of age-related macular degeneration. Mol Vis. 2007, 13: 196-205.
CAS
PubMed Central
PubMed
Google Scholar
Haddad S, Chen CA, Santangelo SL, Seddon JM: The genetics of age-related macular degeneration: a review of progress to date. Surv Ophthalmol. 2006, 51 (4): 316-363. 10.1016/j.survophthal.2006.05.001.
Article
PubMed
Google Scholar
Edwards AO, Ritter R, Abel KJ, Manning A, Panhuysen C, Farrer LA: Complement factor H polymorphism and age-related macular degeneration. Science. 2005, 308 (5720): 421-424. 10.1126/science.1110189.
Article
CAS
PubMed
Google Scholar
Haines JL, Hauser MA, Schmidt S, Scott WK, Olson LM, Gallins P, Spencer KL, Kwan SY, Noureddine M, Gilbert JR: Complement factor H variant increases the risk of age-related macular degeneration. Science. 2005, 308 (5720): 419-421. 10.1126/science.1110359.
Article
CAS
PubMed
Google Scholar
Hageman GS, Anderson DH, Johnson LV, Hancox LS, Taiber AJ, Hardisty LI, Hageman JL, Stockman HA, Borchardt JD, Gehrs KM: A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci USA. 2005, 102 (20): 7227-7232. 10.1073/pnas.0501536102.
Article
CAS
PubMed Central
PubMed
Google Scholar
Rivera A, Fisher SA, Fritsche LG, Keilhauer CN, Lichtner P, Meitinger T, Weber BH: Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk. Hum Mol Genet. 2005, 14 (21): 3227-3236. 10.1093/hmg/ddi353.
Article
CAS
PubMed
Google Scholar
Jakobsdottir J, Conley YP, Weeks DE, Mah TS, Ferrell RE, Gorin MB: Susceptibility genes for age-related maculopathy on chromosome 10q26. Am J Hum Genet. 2005, 77 (3): 389-407. 10.1086/444437.
Article
CAS
PubMed Central
PubMed
Google Scholar
Gold B, Merriam JE, Zernant J, Hancox LS, Taiber AJ, Gehrs K, Cramer K, Neel J, Bergeron J, Barile GR: Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration. Nat Genet. 2006, 38 (4): 458-462. 10.1038/ng1750.
Article
CAS
PubMed Central
PubMed
Google Scholar
Jakobsdottir J, Conley YP, Weeks DE, Ferrell RE, Gorin MB: C2 and CFB genes in age-related maculopathy and joint action with CFH and LOC387715 genes. PLoS ONE. 2008, 3 (5): e2199-10.1371/journal.pone.0002199.
Article
PubMed Central
PubMed
Google Scholar
Chen YH, Liu CK, Chang SC, Lin YJ, Tsai MF, Chen YT, Yao A: GenoWatch: a disease gene mining browser for association study. Nucleic Acids Res. 2008, W336-340. 10.1093/nar/gkn214. 36 Web Server
Strimmer K: A unified approach to false discovery rate estimation. BMC Bioinformatics. 2008, 9: 303-10.1186/1471-2105-9-303.
Article
PubMed Central
PubMed
Google Scholar
Dye WW, Gleason RL, Wilson E, Humphrey JD: Altered biomechanical properties of carotid arteries in two mouse models of muscular dystrophy. J Appl Physiol. 2007, 103 (2): 664-672. 10.1152/japplphysiol.00118.2007.
Article
CAS
PubMed
Google Scholar
Xie Y, Pan W, Khodursky AB: A note on using permutation-based false discovery rate estimates to compare different analysis methods for microarray data. Bioinformatics. 2005, 21 (23): 4280-4288. 10.1093/bioinformatics/bti685.
Article
CAS
PubMed
Google Scholar
Wakefield J: Reporting and interpretation in genome-wide association studies. Int J Epidemiol. 2008, 37 (3): 641-653. 10.1093/ije/dym257.
Article
PubMed
Google Scholar