U.S. H-type BSE (B14842): reticular formation. (A and B) Intraglial PrPSc deposition pattern, marked by arrows; inset for each shows higher magnification for the marked glial cells indicated by the arrow with an asterisk. (C and D) Intraneuronal PrPSc deposition pattern. (A and C) AP IHC method; (B and D) HRP IHC method. Bar = 50 μm.