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Table 1 The distribution of G4 motifs in differentially expressed genes (Illumina IDs) after PhenDC3 and 360A treatment

From: Bisquinolinium compounds induce quadruplex-specific transcriptome changes in HeLa S3 cell lines

 

Illumina IDs

No. of Genes (with G4 motif)

No. of G4 motifs

Average loop length

unchangeda

  

9,456

3.7

8979A -up-regulatedb

117

83

  

8979A -down-regulatedb

85

55

  

PhenDC3 - up-regulatedb

1529

1242 (975)

3,566

3.7

PhenDC3 - down-regulatedb

1157

970 (829)

2,405

3.7

360A - up-regulatedb

401

312 (233)

772

3.8

360A - down-regulatedb

249

215 (136)

337

3.8

  1. a non-differentially expressed genes common in all the gene sets, anova > 0.75
  2. bdifferentially expressed genes, anova ≤ 0.5 and correlation ≥ 0.9