From: Domain analysis of symbionts and hosts (DASH) in a genome-wide survey of pathogenic human viruses
Pfam domain | Domain name | Function | Viral | Human | Human homologs | |||
---|---|---|---|---|---|---|---|---|
E-value range | Median domain coverage | E-value range | Median domain coverage | Human seq. hits per virus | ||||
PF06407 | Borna disease virus P40 | Target for MHC class I-restricted cytotoxic T-cell response | 2.4e-266 - 2.4e-266 | 1.00 | 4.6e-7 - 2.5e-77 | 0.52 | 6 | Endogenous, Bornavirus-like nucleoprotein 1, Endogenous Bornavirus-like nucleoprotein 2 |
PF01728 | FtsJ-like methyltransferase | Methyltransferase | 7.8e-4 - 1.8e-6 | 0.52 | 6.6e-6 - 2.4e-66 | 0.65 | 43 | Many c |
PF14314 | Virus-capping methyltransferase | Virus-capping methyltransferase | 4.1e-84 - 2.9e-106 | 0.98 | 5.1e-04 - 5.1e-04 | 0.10 | 1 | Hypothetical protein |
PF00642 | Zinc finger | Mediates binding specificity | 4.5e-05 - 4.5e-05 | 0.89 | 1.0e-3 - 6.5e-13 | 0.93 | 294 | Many c |
PF12803 a | mRNA methyltransferase | Cap methylation of mRNA. | 9.0e-93 - 4.6e-117 | 1.00 | 1.4e-4 - 2.5e-4 | 0.37 | 3 | Putative ADP-ribosylation factor-like protein 5C, hCG31412, isoform CRA_a, hCG31412, isoform CRA_b |
PF00429 a | ENV polyprotein (coat polyprotein) | Coat polyprotein | 1.0e-03 - 1.0e-03 | 0.17 | 9e-4 - 1.6e-68 | 0.27 | 51 | Many c |
PF00523b | Fusion glycoprotein (F0) | Viral attachement | 7.4e-96 – 8.8e-189 | 1.00 | 1.4e-64 - 1.4e-64 | 0.44 | 1 | Angrgm-52 |
PF00661 b | Viral matrix protein (M) | Viral assembly | 4.1e-84 – 2.3e-146 | 0.99 | 2.9e-106 - 2.9e-106 | 0.37 | 1 | Angrem52 |
PF14313 b | N-terminal Paramyxovirinae phosphoprotein (P) | Phosphoprotein | 4e-4 - 2e-26 | 0.95 | 1.4e-21 - 1.4e-21 | 0.98 | 1 | AngRem104 |
PF13825 b | N-terminal Paramyxovirus structural protein (V/P) | Structural protein | 7.6e-4 - 5.4e-153 | 0.75 | 2.2e-4 - 2.2e-4 | 0.42 | 1 | AngRem104 |