Sanyal AJ: NASH a global health problem. Hepatol Res. 2011, 41: 670-674.
Article
PubMed
Google Scholar
Tannapfel A, Denk H, Dienes HP, Langner C, Schirmacher P, Trauner M, Flott-Rahmel B: Histopathological diagnosis of non-alcoholic and alcoholic fatty liver disease. Virchows Arch. 2011, 458: 511-523.
Article
PubMed
CAS
Google Scholar
Petta S, Muratore C, Craxi A: Non-alcoholic fatty liver disease pathogenesis: the present and the future. Dig Liver Dis. 2009, 41: 615-625.
Article
PubMed
CAS
Google Scholar
Farrell GC, Larter CZ: Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology. 2006, 43 (2 Suppl 1): 99-112.
Article
Google Scholar
Starley BQ, Calcagno CJ, Harrison SA: Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection. Hepatology. 2010, 51: 1820-1832.
Article
PubMed
Google Scholar
Park SK, Seo MH, Shin HC, Ryoo JH: The clinical availability of non-alcoholic fatty liver disease as an early predictor of type 2 diabetes mellitus in korean men: 5-years’ prospective cohort study. Hepatology. 2013, 57: 1378-1383.
Article
PubMed
CAS
Google Scholar
Lee SP: Non-alcoholic fatty liver disease, a marker of subclinical atherosclerosis applicable only to metabolic syndrome?: Time to organize the connection between metabolism and atherosclerosis. J Cardiovasc Ultrasound. 2012, 20: 124-125.
Article
PubMed
PubMed Central
Google Scholar
Buechler C, Wanninger J, Neumeier M: Adiponectin, a key adipokine in obesity related liver diseases. World J Gastroenterol. 2011, 17: 2801-2811.
PubMed
CAS
PubMed Central
Google Scholar
Marchesini G, Bugianesi E, Forlani G, Cerrelli F, Lenzi M, Manini R, Natale S, Vanni E, Villanova N, Melchionda N, Rizzetto M: Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome. Hepatology. 2003, 37: 917-923.
Article
PubMed
Google Scholar
Postic C, Girard J: Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engeneered mice. J Clin Invest. 2008, 118: 829-838.
Article
PubMed
CAS
PubMed Central
Google Scholar
Wree A, Kahraman A, Gerken G, Canbay A: Obesity affects the liver - the link between adipocytes and hepatocytes. Digestion. 2011, 83: 124-133.
Article
PubMed
Google Scholar
Sanjari M, Khodashahi M, Gholamhoseinian A, Shokooki M: Association of adiponectin and metabolic syndrome in women. J Res Med Sci. 2011, 16: 1532-40.
PubMed
PubMed Central
Google Scholar
Gokulakrishnan K, Anjana RM, Indulekha K, Anuradha S, Mohan V: Association of hypoadiponectinemia with non-alcoholic fatty liver disease in urban south Indians–(CURES - 81). Indian J Med Res. 2010, 132: 271-277.
PubMed
CAS
Google Scholar
Mendez-Sanchez N, Chavez-Tapia NC, Villa AR, Sanchez-Lara K, Zamona-Valdes D, Ramos MH, Uribe M: Adiponectin as a protective factor in hepatic steatosis. World J Gastroenterol. 2005, 11: 1737-1741.
Article
PubMed
CAS
PubMed Central
Google Scholar
Pisto P, Ukkola O, Santaniemi M, Kesäniemi YA: Plasma adiponectin - an independent indicator of liver fat accumulation. Metabolism. 2011, 60: 1515-1520.
Article
PubMed
CAS
Google Scholar
Bugianesi E, Pagotto U, Manini R, Vanni E, Gastaldelli A, de Iasio R, Gentilcore E, Natale S, Cassader M, Rizzetto M, Pasquali R, Marchesini G: Plasma adiponectin in nonalcoholic fatty liver is related to hepatic insulin resistance and hepatic fat content, not to liver disease severity. J Clin Endocrinol Metab. 2005, 90: 3498-3504.
Article
PubMed
CAS
Google Scholar
Böttner A, Kratsch J, Müller G, Kapellen TM, Blüher S, Keller E, Blüher M, Kiess W: Gender differences of adiponectin levels develop during the progression of puberty and are relared to serum androgen levels. J Clin Endocrinol Metab. 2004, 89: 4053-4062.
Article
PubMed
Google Scholar
Horenburg S, Fischer-Posovszky P, Debatin KM, Wabitsch M: Influence of sex hormones on adiponectin expression in human adipocytes. Horm Metab Res. 2008, 40: 779-786.
Article
PubMed
CAS
Google Scholar
Mohammadzadeh G, Zarghami N: Hypoadiponectinemia in obese subjects with type II diabetes: A close association with central obesity indices. J Res Med Sci. 2011, 16: 713-723.
PubMed
CAS
PubMed Central
Google Scholar
Kishida K, Kim KK, Funahashi T, Matsuzawa Y, Kang HC, Shimomura I: Relationships between circulating adiponectin levels and fat distribution in obese subjects. J Atheroscler Thromb. 2011, 18: 592-595.
Article
PubMed
CAS
Google Scholar
Hanley AJ, Bowden D, Wagenknecht LE, Balasubramanyam A, Langfeld C, Saad MF, Rotter JI, Guo X, Chen YD, Bryer-Ash M, Norris JM, Haffner SM: Association of adiponectin with body fat distribution and insulin sensitivity in nondiabetic Hispanics and African-Americans. J Clin Endocrinol Metab. 2007, 92: 2665-2671.
Article
PubMed
CAS
Google Scholar
Mujumdar PP, Duerksen-Hughes PJ, Firek AF, Hessinger DA: Long-term, progressive, aerobic training increases adiponectin in middle-aged, overweight, untrained males and females. Scand J Clin Lab Invest. 2011, 71: 101-107.
PubMed
CAS
Google Scholar
Kelly KR, Blaszczak A, Haus JM, Patrick-Melin A, Fealy CE, Solomon TP, Kalinski MI, Kirwan JP: A 7-d exercise program increases high-molecular weight adiponectin in obese adults. Med Sci Sports Exerc. 2012, 44: 69-74.
Article
PubMed
CAS
Google Scholar
Thoma C, Day CP, Trenell MI: Lifestyle interventions for the treatment of non-alcoholic fatty liver disease in adults: a systematic review. J Hepatol. 2012, 56: 255-266.
Article
PubMed
Google Scholar
Brookes MJ, Igbal TH, Cooper BT: Hypertension and hepatic steatosis. Curr Hypetens Rep. 2008, 10: 182-187.
Article
CAS
Google Scholar
Lau K, Lorbeer R, Haring R, Schmidt CO, Wallaschofski H, Nauck M, John U, Baumeister SE, Völzke H: The association between fatty liver disease and blood pressure in a population-based prospective longitudinal study. J Hypertens. 2010, 28: 1829-1835.
Article
PubMed
CAS
Google Scholar
Lopez-Suarez A, Guerrero JM, Elvirs-Gonzalez J, Beltran-Robles M, Canas-Hormigo F, Bascunana-Quirell A: Nonalcoholic fatty liver disease is associated with blood pressure in hypertensive and nonhypertensive individuals from the general population with normal levels of alanine aminotransferase. Eur J Gastrenterol Hepatol. 2011, 23: 1011-1017.
CAS
Google Scholar
Kantartzis K, Rittig K, Balletshofer B, Machann J, Schick F, Porubska K, Fritsche A, Häring HU, Stefan N: The relationships of plasma adiponectin with a favorable lipid profile, decreased inflammation, and less ectopic fat accumulation depend on adiposity. Clin Chem. 2006, 52: 1934-1942.
Article
PubMed
CAS
Google Scholar
Yamauchi T, Kamon J, Ito Y, Suchida A, Yokomizo T, Kita S, Sugiyama T, Miyagishi M, Hara K, Tsunoda M, Murakami K, Ohteki T, Uchida S, Takekawa S, Waki H, Tsuno NH, Shibata Y, Terauchi Y, Froguel P, Tobe K, Koyasu S, Taira K, Kitamura T, Shimizu T, Nagai R, Kadowaki T: Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature. 2003, 423: 762-769.
Article
PubMed
CAS
Google Scholar
Verges B, Petit JM, Duvillard L, Dautin G, Florentin E, Galland F, Gambert P: Adiponectin is an important determinant of apoA-I catabolism. Arterioscler Thromb Vasc Biol. 2006, 26: 1364-1369.
Article
PubMed
CAS
Google Scholar
Lin SX, Pi-Sunyer EX: Prevalence of the metabolic syndrome among US middle-aged and older adults with and without diabetes - a prliminary analysis of the NHANES 1999–2002 data. Ethn Dis. 2007, 17: 35-39.
PubMed
Google Scholar
Ohashi K, Ouchi N, Matszawa Y: Anti-inflammatory and anti-atherogenic properties of adiponectin. Biochimie. 2012, 94: 2137-2142.
Article
PubMed
CAS
Google Scholar
Moschen AR, Wieser V, Tilg H: Adiponectin: key player in the adipose tissue-liver crosstalk. Curr Med Chem. 2012, 19: 5467-
Article
PubMed
CAS
Google Scholar
Xu A, Wang Y, Keshaw H, Xu L, Lam KS, Cooper GJ: The fat-derived hormone adiponectin alleviates alcoholic and non-alcoholic fatty liver disease in mice. J Clin Invest. 2003, 112: 91-100.
Article
PubMed
CAS
PubMed Central
Google Scholar
Kim JY, Ahn SV, Yoon JH, Koh SB, Yoon J, Yoo BS, Lee SH, Park JK, Choe KH, Guallar E: Prospective study of serum adiponectin and incident metabolic syndrome: the ARIRANG Study. Diabetes Care. 2012, 36: 1547-1553.
Article
PubMed
Google Scholar
Juonala M, Saarikoski LA, Vikari JS, Oikonen M, Lehtimäki T, Lyytikäinen LP, Huupponen R, Magnussen CG, Koskinen J, Laitinen T, Taittonen L, Kähönen M, Kivimäki M, Raitakari OT: A longitudinal analysis on associations of adiponectin levels with metabolic syndrome and carotid artery intima-media thickness. The Cardivascular Risk in Young Finns Study. Atherosclerosis. 2011, 217: 234-239.
CAS
Google Scholar
Joosten MM, Beulens JW, Kersten S, Hendriks HF: Moderate alcohol consumption increases insulin sensitivity and ADIPOQ expression in postmenopausal women: a randomised, crossover trial. Diabetologia. 2008, 51: 1375-1381.
Article
PubMed
CAS
PubMed Central
Google Scholar
Imhof A, Plamper I, Maier S, Rischler G, Koenig W: Effect of drinking on adiponectin in healthy men and women: a randomized intervention study of water, ethanol, red wine, and beer with or without alcohol. Diabetes Care. 2009, 32: 1101-1103.
Article
PubMed
CAS
PubMed Central
Google Scholar
Nishise Y, Saito T, Makino N, Okumoto K, Ito JI, Watanabe H, Saito K, Togashi H, Ikeda C, Kubota I, Daimon M, Kato T, Fukao A, Kawata S: Relationship between alcohol consumption and serum adiponectin levels: the Takahata study - a cross-sectional study of a healthy Japanese population. J Clin Endocrinol Metab. 2010, 95: 3828-3835.
Article
PubMed
CAS
Google Scholar
Iwashima Y, Katsuya T, Ishikawa K, Kida I, Ohishi M, Horio T, Ouchi N, Ohashi K, Kihara S, Funahashi T, Rakugi H, Ogihara T: Association of hypoadiponectinemia with smoking habit in men. Hypertension. 2005, 45: 1094-1100.
Article
PubMed
CAS
Google Scholar
Tsai JS, Guo FR, Chen SC, Lue BH, Lee LT, Huang KC, Chen CY, Hung SH, Chuang LM, Chen CY: Changes of serum adiponectin and soluable intercellular adhesion molecule-1 concentrations after smoking cessation. Clin Chem Lab Med. 2012, 50: 1063-1069.
Article
PubMed
CAS
Google Scholar
Hashemi M, Hanafi Bojd H, Eskandari Nasab E, Bahari A, Hashemzehi NA, Shafieipour S, Narouie B, Taheri M, Ghavami S: Association of adiponectin rs266729 gene polymorphism with nonalcoholic fatty liver disease. Hepat Mon. 2013, 13: e9527-
Article
PubMed
PubMed Central
Google Scholar
Musso G, Bo S, Cassader M, De Michieli F, Gambino R: Impact of sterol regulatory element-binding factor-1c polymorphism on incidence of nonalcoholic fatty liver disease and on severity of liver disease and of glucose and lipid dysmetabolism. Am J Clin Nutr. 2013, 98: 895-906.
Article
PubMed
CAS
Google Scholar
Peng XE, Wu YL, Lin SW, Lu QQ, Hu ZJ, Lin X: Genetic variants in PNPLA3 and risk of non-alcoholic fatty liver disease. Plos One. 2012, 7: e50256-
Article
PubMed
CAS
PubMed Central
Google Scholar
Lin YC, Chang PF, Hu FC, Yang WS, Chang MH, Ni YH: A common variant in the PNPLA3 gene is a risk factor for non-alcoholic fatty liver disease in obese Taiwanese children. J Pediatr. 2011, 158: 740-744.
Article
PubMed
CAS
Google Scholar
Valenti L, Rametta R, Ruscica M, Dongiovanni P, Steffani L, Motta BM, Canavesi E, Fracanzani AL, Mozzi E, Roviaro G, Magni P, Fargion S: The l148 PNPLA3 polymorphism influences serum adiponectin in patients with fatty liver and healthy controls. BMC Gastroenterol. 2012, 12: 111-
Article
PubMed
CAS
PubMed Central
Google Scholar
Padmalayam I, Suto M: Role of adiponectin in the metabolic syndrome: current perspectives on its modulation as a treatment strategy. Curr Pharm Des. 2013, 19: 5755-5763.
Article
PubMed
CAS
Google Scholar
Whitehead JP, Richards AA, Hickman IJ, Macdonald GA, Prins JB: Adiponectin–a key adipokine in the metabolic syndrome. Diabetes Obes Metab. 2006, 8: 264-280.
Article
PubMed
CAS
Google Scholar
Yamauchi T, Kadowaki T: Physiological and pathophysiological roles of adiponectin and adiponectin receptors in the integrated regulation of metabolic and cardiovascular diseases. Int J Obes. 2008, 32 (Suppl 7): 13-18.
Article
Google Scholar
Lanni F, Santulli G, Izzo R, Rubattu S, Zanda B, Volpe M, Iaccarino G, Trimarco B: The PI(A1/A2) polymorphism of glycoprotein IIIa and cerebrovascular events in hypertension: Increased risk of ischemic stroke in high-risk patients. J Hypertens. 2007, 25: 551-556.
Article
PubMed
CAS
Google Scholar
Galasso G, Santulli G, Piscione F, De Rosa R, Trimarco V, Piccolo R, Cassese S, Iaccarino G, Trimarco B, Chiariello M: The GPIIIa PIA2 polymorphism is associated with an increased risk of cardiovascular adverse events. BMC Cardiovasc Disord. 2010, 10: 41-
Article
PubMed
PubMed Central
Google Scholar
Santulli G, Cipoletta E, Sorriento D, Del Giudice C, Anastasio A, Monaco S, Maione AS, Condorelli G, Puca A, Trimarco B, Illario M, Iaccarino G: CaMK4 gene deletion induces hypertension. J Am Heart Assoc. 2012, 1: e001081-
Article
PubMed
PubMed Central
Google Scholar
Haenle MM, Brockmann SO, Kron M, Bertling U, Mason RA, Steinbach G, Boehm BO, Koenig W, Kern P, Piechotowski I, Kratzer W, EMIL-Study group: Overweight, physical activity, tobacco and alcohol consumption in a cross-sectional random sample of German adults. BMC Public Health. 2006, 6: 233-
Article
PubMed
PubMed Central
Google Scholar
Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, Fruchart JC, James WP, Loria CM, Smith SC, International Diabetes Federation Task Force on Epidemiology and Prevention; Hational Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; International Association for the Study of Obesity: Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009, 120: 1640-1645.
Article
PubMed
CAS
Google Scholar
Sanyal AJ: AGA technical review on nonalcoholic fatty liver disease. Gastroenterolgy. 2002, 123: 1705-1725.
Article
Google Scholar
Kratzer W, Akinli AS, Bommer M, Arnold F, Eggink S, Imhof A, Mason RA, Klaus J, Schuler A, Boehm BO, Haenle MM: Prevalence and risk factors of focal sparing in hepatic steatosis. Ultraschall Med. 2010, 31: 37-42.
Article
PubMed
CAS
Google Scholar