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Table 6 Fold change of gene expression in endothelial cells exposed to bevacizumab compared to endothelial cells exposed to ranibizumab

From: Gene profiling of human VEGF signaling pathways in human endothelial and retinal pigment epithelial cells after anti VEGF treatment

Gene symbol

Gene name

Bevacizumab/ranibizumab

Grade

KDR

Kinase insert domain receptor

+5.547

A

NOS3

Nitric oxide synthase 3 (endothelial cell)

+86.3228

A

NFATC2

Nuclear factor of activated T-cells

-3.3708

A

PLA2G2E

Phospholipase A2, group IIE

-11.1207

B

PRKCG

Protein kinase C, gamma

-5.3751

B