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Table 1 Baseline characteristics of patients with invasive candidiasis (IC)

From: Epidemiology of invasive candidiasis in a surgical intensive care unit: an observational study

Characteristics

Yeast infection, n = 22

Age (years), median (IQR)

66 (53.7–74.2)

Male sex, n (%)

16 (72.7)

Comorbidities, n (%)

21 (95.4)

 Chronic renal failure, n (%)

3 (13.6)

 Diabetes mellitus, n (%)

7 (31.8)

 Solid tumor, n (%)

7 (31.8)

Steroid therapy, n (%)

0 (0)

Parenteral nutrition, n (%)

14 (63.6)

Mechanical ventilation, n (%)

20 (90.9)

Urinary catheter, n (%)

22 (100)

Central venous catheter (CVC), n (%)

22 (100)

CVC removed, n (%)

22 (100)

Yeast positivity in removed CVC, n (%)

2 (9.1)

Previous hospitalization, n (%)

16 (72.7)

Pre-IC diagnosis LOS (days), median (IQR)

20 (5–37.5)

LOS >7 days, n (%)

15 (68.2)

Admission typology

 Surgical pathology, n (%)

20 (90.9)

 Medical pathology, n (%)

2 (9.1)

 Trauma, n (%)

0 (0)

Abdominal surgery, n (%)

14 (63.6)

SOFA scorea on IC diagnosis, median (IQR)

5 (3–6.2)

Empirical therapy duration (days), median (IQR)

10 (5–16.5)

Previous antibiotic therapy, n (%)

21 (95.4)

Concomitant bacterial infection, n (%)

20 (90.9)

Concomitant bacteremia, n (%)

9 (40.9)

Fungemia, n (%)

9 (40.9)

Fungemia duration (days), median (IQR)

7 (9.5–14.5)

Previous fungal invasive infection, n (%)

2 (9.1)

C. albicans species, n (%)

13 (59.1)

Fungal multifocal colonization, n (%)

8 (36.4)

Colonization and infection species coincidence, n (%)

6 (75)

Mortality (global), n (%)

3 (13.6)

 Early mortality (≤7 days), n (%)

2 (9.1)

 Late mortality (>7 days), n (%)

1 (4.5)

Mortality in presence of fungemia, n (%)

3 (33.3)

Mortality in absence of fungemia, n (%)

0 (0)

  1. CVC Central venous catheter, IQR interquartile range, LOS length of stay, SOFA sequential organ failure assessment
  2. aIn the two patients who developed invasive candidiasis prior to ICU admission, their SOFA score was calculated at ICU admission