Vissink A, Jansma J, Spijkervet FK, Burlage FR, Coppes RP. Oral sequelae of head and neck radiotherapy. Crit Rev Oral Biol Med. 2003;14:199–212.
Article
CAS
PubMed
Google Scholar
Fujita M, Tanimoto K, Wada T. Early radiographic changes in radiation bone injury. Oral Surg Oral Med Oral Pathol. 1986;61:641–4.
Article
CAS
PubMed
Google Scholar
Randall K, Stevens J, Yepes JF, Randall ME, Kudrimoti M, Feddock J, Xi J, Kryscio RJ, Miller CS. Analysis of factors influencing the development of xerostomia during intensity-modulated radiotherapy. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;115:772–9.
Article
PubMed Central
PubMed
Google Scholar
Burlage FR, Coppes RP, Meertens H, Stokman MA, Vissink A. Parotid and submandibular/sublingual salivary flow during high dose radiotherapy. Radiother Oncol. 2001;61:271–4.
Article
CAS
PubMed
Google Scholar
Braam PM, Roesink JM, Raaijmakers CP, Busschers WB, Terhaard CH. Quality of life and salivary output in patients with head-and-neck cancer five years after radiotherapy. Radiat Oncol. 2007;2:3.
Article
PubMed Central
PubMed
Google Scholar
Van Nieuw Amerongen A, Bolscher JG, Veerman EC. Salivary proteins: protective and diagnostic value in cariology? Caries Res. 2004;38:247–53.
Article
CAS
PubMed
Google Scholar
Baker OJ, Edgerton M, Kramer JM, Ruhl S. Saliva-microbe interactions and salivary gland dysfunction. Adv Dent Res. 2014;26:7–14.
Article
CAS
PubMed
Google Scholar
Aguiar GP, Jham BC, Magalhaes CS, Sensi LG, Freire AR. A review of the biological and clinical aspects of radiation caries. J Contemp Dent Pract. 2009;10:83–9.
PubMed
Google Scholar
Almstahl A, Wikstrom M, Groenink J. Lactoferrin, amylase and mucin MUC5B and their relation to the oral microflora in hyposalivation of different origins. Oral Microbiol Immunol. 2001;16:345–52.
Article
CAS
PubMed
Google Scholar
Brown LR, Dreizen S, Rider LJ, Johnston DA. The effect of radiation-induced xerostomia on saliva and serum lysozyme and immunoglobulin levels. Oral Surg Oral Med Oral Pathol. 1976;41:83–92.
Article
CAS
PubMed
Google Scholar
Funegard U, Franzen L, Ericson T, Henriksson R. Parotid saliva composition during and after irradiation of head and neck cancer. Eur J Cancer B Oral Oncol. 1994;30B:230–3.
Article
CAS
PubMed
Google Scholar
Valdez IH, Atkinson JC, Ship JA, Fox PC. Major salivary gland function in patients with radiation-induced xerostomia: flow rates and sialochemistry. Int J Radiat Oncol Biol Phys. 1993;25:41–7.
Article
CAS
PubMed
Google Scholar
Almstahl A, Wikstrom M. Oral microflora in subjects with reduced salivary secretion. J Dent Res. 1999;78:1410–6.
Article
CAS
PubMed
Google Scholar
Almstahl A, Wikstrom M, Fagerberg-Mohlin B. Microflora in oral ecosystems in subjects with radiation-induced hyposalivation. Oral Dis. 2008;14:541–9.
Article
CAS
PubMed
Google Scholar
Epstein JB, Chin EA, Jacobson JJ, Rishiraj B, Le N. The relationships among fluoride, cariogenic oral flora, and salivary flow rate during radiation therapy. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998;86:286–92.
Article
CAS
PubMed
Google Scholar
Keene HJ, Fleming TJ. Prevalence of caries-associated microflora after radiotherapy in patients with cancer of the head and neck. Oral Surg Oral Med Oral Pathol. 1987;64:421–6.
Article
CAS
PubMed
Google Scholar
Hannig M, Dounis E, Henning T, Apitz N, Stosser L. Does irradiation affect the protein composition of saliva? Clin Oral Investig. 2006;10:61–5.
Article
CAS
PubMed
Google Scholar
Christensen ME, Hansen HS, Poulsen SS, Bretlau P, Nexo E. Immunohistochemical and quantitative changes in salivary EGF, amylase and haptocorrin following radiotherapy for oral cancer. Acta Otolaryngol. 1996;116:137–43.
Article
CAS
PubMed
Google Scholar
Dijkema T, Terhaard CH, Roesink JM, Raaijmakers CP, van den Keijbus PA, Brand HS, Veerman EC. MUC5B levels in submandibular gland saliva of patients treated with radiotherapy for head-and-neck cancer: a pilot study. Radiat Oncol. 2012;7:91.
Article
PubMed Central
PubMed
Google Scholar
Makkonen TA, Tenovuo J, Vilja P, Heimdahl A. Changes in the protein composition of whole saliva during radiotherapy in patients with oral or pharyngeal cancer. Oral Surg Oral Med Oral Pathol. 1986;62:270–5.
Article
CAS
PubMed
Google Scholar
Almstahl A, Wikstrom M. Electrolytes in stimulated whole saliva in individuals with hyposalivation of different origins. Arch Oral Biol. 2003;48:337–44.
Article
CAS
PubMed
Google Scholar
Denny P, Hagen FK, Hardt M, Liao L, Yan W, Arellanno M, Bassilian S, Bedi GS, Boontheung P, Cociorva D, et al. The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions. J Proteome Res. 2008;7:1994–2006.
Article
PubMed Central
CAS
PubMed
Google Scholar
Schipper R, Loof A, de Groot J, Harthoorn L, van Heerde W, Dransfield E. Salivary protein/peptide profiling with SELDI-TOF-MS. Ann N Y Acad Sci. 2007;1098:498–503.
Article
CAS
PubMed
Google Scholar
Al-Tarawneh SK, Bencharit S. Applications of surface-enhanced laser desorption/ionization time-of-flight (SELDI-TOF) mass spectrometry in defining salivary proteomic profiles. Open Dent J. 2009;3:74–9.
Article
PubMed Central
CAS
PubMed
Google Scholar
Schipper R, Loof A, de Groot J, Harthoorn L, Dransfield E, van Heerde W. SELDI-TOF-MS of saliva: methodology and pre-treatment effects. J Chromatogr B Analyt Technol Biomed Life Sci. 2007;847:45–53.
Article
CAS
PubMed
Google Scholar
Shintani S, Hamakawa H, Ueyama Y, Hatori M, Toyoshima T. Identification of a truncated cystatin SA-I as a saliva biomarker for oral squamous cell carcinoma using the SELDI ProteinChip platform. Int J Oral Maxillofac Surg. 2010;39:68–74.
Article
CAS
PubMed
Google Scholar
Streckfus CF, Bigler LR, Zwick M. The use of surface-enhanced laser desorption/ionization time-of-flight mass spectrometry to detect putative breast cancer markers in saliva: a feasibility study. J Oral Pathol Med. 2006;35:292–300.
Article
CAS
PubMed
Google Scholar
Ryu OH, Atkinson JC, Hoehn GT, Illei GG, Hart TC. Identification of parotid salivary biomarkers in Sjogren’s syndrome by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry and two-dimensional difference gel electrophoresis. Rheumatology (Oxford). 2006;45:1077–86.
Article
CAS
Google Scholar
Gallo A, Martini D, Sernissi F, Giacomelli C, Pepe P, Rossi C, Riveros P, Mosca M, Alevizos I, Baldini C. Gross cystic disease fluid protein-15(GCDFP-15)/prolactin-inducible protein (PIP) as functional salivary biomarker for primary sjogren’s syndrome. J Genetic Syndrome Gene Therapy 2013;4:140. doi:10.4172/2157-7412.1000140.
Google Scholar
Range H, Leger T, Huchon C, Ciangura C, Diallo D, Poitou C, Meilhac O, Bouchard P, Chaussain C. Salivary proteome modifications associated with periodontitis in obese patients. J Clin Periodontol. 2012;39:799–806.
Article
CAS
PubMed
Google Scholar
Imanguli MM, Atkinson JC, Harvey KE, Hoehn GT, Ryu OH, Wu T, Kingman A, Barrett AJ, Bishop MR, Childs RW, et al. Changes in salivary proteome following allogeneic hematopoietic stem cell transplantation. Exp Hematol. 2007;35:184–92.
Article
PubMed Central
CAS
PubMed
Google Scholar
Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Roy Stat Soc Ser B (Methodol). 1995;57:289–300.
Google Scholar
Vidotto A, Henrique T, Raposo LS, Maniglia JV, Tajara EH. Salivary and serum proteomics in head and neck carcinomas: before and after surgery and radiotherapy. Cancer Biomark. 2010;8:95–107.
CAS
PubMed
Google Scholar
Henskens YM, Veerman EC, Mantel MS, van der Velden U, Nieuw Amerongen AV. Cystatins S and C in human whole saliva and in glandular salivas in periodontal health and disease. J Dent Res. 1994;73:1606–14.
CAS
PubMed
Google Scholar
Yamagishi H, Fitzgerald DH, Sein T, Walsh TJ, O’Connell BC. Saliva affects the antifungal activity of exogenously added histatin 3 towards Candida albicans. FEMS Microbiol Lett. 2005;244:207–12.
Article
CAS
PubMed
Google Scholar
Sugimoto J, Kanehira T, Mizugai H, Chiba I, Morita M. Relationship between salivary histatin 5 levels and Candida CFU counts in healthy elderly. Gerodontology. 2006;23:164–9.
Article
PubMed
Google Scholar
Oudhoff MJ, Bolscher JG, Nazmi K, Kalay H, van’t Hof W, Amerongen AV, Veerman EC. Histatins are the major wound-closure stimulating factors in human saliva as identified in a cell culture assay. FASEB J. 2008;22:3805–12.
Article
CAS
PubMed
Google Scholar
Striz I, Trebichavsky I. Calprotectin—a pleiotropic molecule in acute and chronic inflammation. Physiol Res. 2004;53:245–53.
CAS
PubMed
Google Scholar
Sweet SP, Denbury AN, Challacombe SJ. Salivary calprotectin levels are raised in patients with oral candidiasis or Sjogren’s syndrome but decreased by HIV infection. Oral Microbiol Immunol. 2001;16:119–23.
Article
CAS
PubMed
Google Scholar
Dodds MW, Johnson DA, Yeh CK. Health benefits of saliva: a review. J Dent. 2005;33:223–33.
Article
PubMed
Google Scholar