Fig. 3

Effect of epiplakin knockdown on cell proliferation. Control and epiplakin-knockdowned cells were grown in wells of 96-well plates and Alamar blue dye was supplemented the culture medium. Relative absorbance of Alamar blue dye reaction in the medium was monitored to examine the activity of cell proliferation. Epiplakin-siRNA knockdown significantly promoted cell proliferation as compared with control siRNA culture at 30 and 60 min (Fig. 3). Evaluated as 95 % significant with the p value of 1.07032763506866 × 10 (−13) (< 0.101,076) in the datum of 30 min, and p value = 1.87138814984332 × 10 (−8) (p < 0.028528) in the datum of 60 min