Fig. 4

Effect of epiplakin knockdown on protein expression of vimentin, E-cadherin and keratin 6. Control and epiplakin-knockdowned cells were grown in wells of 60-min culture dishes and the cells were collected for western blotting for vimentin, E-cadherin and keratin 6 as described in the manuscript. Expression of vimentin (a), E-cadherin (b) and keratin 6 (c) was suppressed by siRNA knockdown of epiplakin as compared with their expression level in cells with control siRNA transfection as detected by using western blotting