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Table 5 Chi squared test for the difference in OI prevalence by geographical location

From: Frequency and distribution patterns of opportunistic infections associated with HIV/AIDS in Uganda

 

Prevalence

p value

Tororo (Eastern Uganda) (n = 6534), n (%)

Mulago (Central Uganda) (n = 7243), n (%)

Mbarara (South-western Uganda) (n = 10,586), n (%)

Before HAART (2001–2003)

 Opportunistic infection

  Geohelminths

2671 (40.9)

1406 (19.4)

2378 (22.5)

<0.0001

  Diarrhoea

2817 (43.1)

1780 (24.6)

2862 (27.0)

<0.0001

  Oral candida

1531 (23.4)

2345 (32.4)

4560 (43.1)

<0.0001

  Bacterial pneumonia

858 (13.1)

896 (12.4)

983 (9.3)

<0.0001

  Mycobacterium tuberculosis

830 (12.7)

875 (12.1)

608 (5.7)

<0.0001

  Genital ulcer

508 (7.8)

697 (9.6)

658 (6.2)

<0.0001

  Confirmed malaria

1072 (16.4)

826 (11.4)

1771 (16.7)

<0.0001

  Esoph candida

261 (4.0)

732 (10.1)

1194 (11.3)

<0.0001

  Herpes zoster

388 (5.9)

423 (5.8)

618 (5.8)

0.098

  Cryptosporidiosis

178 (2.7)

283 (3.9)

434 (4.1)

<0.0001

  Cryptococcosis

160 (2.4)

145 (2.0)

122 (1.2)

<0.0001

  Others

75 (1.1)

204 (2.8)

112 (1.1)

<0.0001

 Opportunistic cancer

  Kaposi’s sarcoma/HHV8

96 (1.5)

61 (0.8)

52 (0.5)

<0.0001

 

Prevalence

p value

Tororo (Eastern Uganda) (n = 16,207),

n (%)

Mulago (Central Uganda) (n = 16,288), n (%)

Mbarara (South western Uganda) (n = 17,047), n (%)

Gulu (Northern Uganda) (n = 10,464), n (%)

Early HAART (2004–2008)

 Opportunistic infection

  Geohelminths

5825 (35.9)

4363 (26.8)

4925 (28.9)

3950 (37.7)

<0.0001

  Diarrhoea

4503 (27.8)

3261 (20.0)

3431 (20.1)

3848 (36.8)

<0.0001

  Oral candida

1966 (12.1)

3632 (22.3)

4097 (24.0)

976 (9.3)

<0.0001

  Mycobacterium tuberculosis

2958 (18.2)

3589 (22.1)

1936 (11.4)

2198 (21.0)

<0.0001

  Bacterial pneumonia

1301 (8.0)

1627 (10.0)

823 (4.8)

829 (7.9)

<0.0001

  Genital ulcer

1373 (8.5)

2046 (12.6)

1474 (8.6)

1229 (11.7)

<0.0001

  Confirmed malaria

893 (5.5)

984 (6.0)

611 (3.6)

1105 (10.6)

<0.0001

  Esoph candida

969 (6.0)

1744 (10.7)

1714 (10.1)

901 (8.6)

<0.0001

  Herpes zoster

1103 (6.8)

1110 (6.8)

970 (5.7)

575 (5.5)

<0.0001

  Cryptosporidiosis

666 (4.1)

467 (2.9)

419 (2.5)

483 (4.6)

<0.0001

  Cryptococcosis

238 (1.5)

337 (2.1)

197 (1.2)

162 (1.5)

<0.0001

  Others

364 (2.2)

647 (4.0)

333 (2.0)

455 (4.3)

<0.0001

 Opportunistic cancer

  Kaposi’s sarcoma/HHV8

209 (1.3)

195 (1.2)

128 (0.8)

145 (1.4)

0.003

 

Prevalence

p value

Tororo (Eastern Uganda) (n = 14,658), n (%)

Mulago (Central Uganda) (n = 17,977), n (%)

Mbarara (South western Uganda) (15,095), n (%)

Gulu (Northern Uganda) (n = 15,152), n (%)

Late HAART (2009–2013)

 Opportunistic infection

  Geohelminths

3270 (22.3)

3373 (18.8)

3169 (21.0)

3991 (26.3)

<0.0001

  Diarrhoea

2786 (19.0)

1949 (10.8)

1653 (11.0)

2585 (17.1)

<0.0001

  Oral candida

731 (5.0)

1822 (10.1)

1617 (10.7)

339 (2.2)

<0.0001

  Bacterial pneumonia

1354 (9.2)

1043 (5.8)

641 (4.2)

1310 (8.6)

<0.0001

  Mycobacterium tuberculosis

780 (5.3)

1088 (6.1)

436 (2.9)

1286 (8.5)

<0.0001

  Genital ulcer

767 (5.2)

1047 (5.8)

1265 (8.4)

704 (4.6)

<0.0001

  Confirmed malaria

769 (5.2)

688 (3.8)

365 (2.4)

562 (3.7)

<0.0001

  Esoph candida

342 (2.3)

640 (3.6)

489 (3.2)

286 (1.9)

<0.0001

  Herpes zoster

581 (4.0)

739 (4.1)

554 (3.7)

396 (2.6)

<0.0001

  Cryptosporidiosis

219 (1.5)

198 (1.1)

140 (0.9)

138 (0.9)

0.011

  Cryptococcosis

198 (1.4)

96 (0.5)

56 (0.4)

67 (0.4)

<0.0001

  Others

356 (2.4)

351 (2.0)

239 (1.6)

203 (1.3)

<0.0001

 Opportunistic cancer

  Kaposi’s sarcoma/HHV8

116 (0.8)

91 (0.5)

58 (0.4)

45 (0.3)

<0.0001

  1. HHV8 human herpes virus 8, n number of patient