From: In silico investigation of mitragynine and 7-hydroxymitragynine metabolism
Parent compound | Position 9 (methyl ether of benzene) | Position 16 (methyl ester of alkene) | Position 17 (methyl ether of alkene) |
---|---|---|---|
M for mitragynine H for 7-hydroxymitragynine | m for original methyl group d for demethylation g for glucuronidation after d s for sulfation after d (4 possible groups and 3 possible steps) | m for original methyl group d for demethylation g for glucuronidation after d (3 possible groups and 2 possible steps) | m for original methyl group d for demethylation o for oxidation after d r for reduction after d G for glucuronidation after r (5 possible groups and 4 possible steps) |