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  1. Cerebrospinal fluid leaks (CSF) result from an abnormal communication between the subarachnoid space and the extracranial space. Approximately 90% of CSF leak at the anterior skull base manifests as rhinorrhea...

    Authors: Carlos Martín-Martín, Gabriel Martínez-Capoccioni, Ramón Serramito-García and Federico Espinosa-Restrepo
    Citation: BMC Research Notes 2012 5:459
  2. Patients have to travel long distances to undergo hemodialysis (HD) in some regions. We aimed to search for an association of the distance between patients’ residence and the dialysis unit with quality of life...

    Authors: Paulo Roberto Santos and Francisco Plácido Nogueira Arcanjo
    Citation: BMC Research Notes 2012 5:458
  3. The aim of this study was to investigate the effect of various classes of clinically relevant antibiotics at sub-lethal concentrations on virulence gene expression and biofilm formation in Staphylococcus aureus.

    Authors: Lene N Nielsen, Michael Roggenbuck, Jakob Haaber, Dan Ifrah and Hanne Ingmer
    Citation: BMC Research Notes 2012 5:457
  4. To evaluate institutional nursing care performance in the context of national comparative statistics (benchmarks), approximately one in every three major healthcare institutions (over 1,800 hospitals) across t...

    Authors: Qingjiang Hou, Brandon Crosser, Jonathan D Mahnken, Byron J Gajewski and Nancy Dunton
    Citation: BMC Research Notes 2012 5:456
  5. Odontogenic tumors are lesions that are derived from remnants of the components of the developing tooth germ. The calcifying cystic odontogenic tumor or calcifying odontogenic cyst is a benign cystic neoplasm ...

    Authors: Ana Paula de Lima, Dárcio Kitakawa, Janete Dias Almeida, Adriana Aigotti Haberbeck Brandão and Ana Lia Anbinder
    Citation: BMC Research Notes 2012 5:455
  6. Gastrointestinal and urinary tract pathogenic infections are aggravating the incidence and progression of the Human Immunodeficiency Virus (HIV) infection into Acquired Immune Deficiency Syndrome (AIDS) more e...

    Authors: Yaw Agyekum Boaitey, Bernard Nkrumah, Ali Idriss and Samuel Crowther Kofi Tay
    Citation: BMC Research Notes 2012 5:454
  7. To study the diagnosis delay and its impact on stage of disease among women with breast cancer on Libya.

    Authors: Eramah Ermiah, Fathi Abdalla, Abdelbaset Buhmeida, Entesar Larbesh, Seppo Pyrhönen and Yrjö Collan
    Citation: BMC Research Notes 2012 5:452
  8. Herpes Simplex Virus Type 2 (HSV-2) is highly prevalent in regions disproportionately affected by the human immunodeficiency virus (HIV-1) epidemic. The objective of our study was to identify the risk factors ...

    Authors: Musie Ghebremichael, Desale Habtzgi and Elijah Paintsil
    Citation: BMC Research Notes 2012 5:451
  9. Striae gravidarum is a physiological skin change that many pregnant women experience during pregnancy. The striae are often accompanied by a reddish purple color during pregnancy, and then lose pigmentation an...

    Authors: Kotomi Yamaguchi, Nobuhiko Suganuma and Kazutomo Ohashi
    Citation: BMC Research Notes 2012 5:450
  10. Musculoskeletal involvement occurs in 25% of patients with non-Hodgkin’s lymphoma (NHL). Primary lymphoma in the joint is rare. It can present as a bone lesion or as atypical soft tissue proliferation. NHL has...

    Authors: Jetze Visser, Vincent JJF Busch, Ineke M de Kievit-van der Heijden and Arno M ten Ham
    Citation: BMC Research Notes 2012 5:449
  11. Pulmonary load of Legionella pneumophila in mice is normally determined by counting serial dilutions of bacterial colony forming units (CFU) on agar plates. This process is often tedious and time consuming. We de...

    Authors: Desmond Koon Yong Ang, Sze Ying Ong, Andrew Stephen Brown, Elizabeth Louise Hartland and Ian Richard van Driel
    Citation: BMC Research Notes 2012 5:448
  12. Cirrhosis produces variety of symptoms which eventually lead to a negative impact on Health Related Quality of Life (HRQOL). The general aim of this study was to evaluate the magnitude of poor HRQOL and to ass...

    Authors: Om Parkash, Romaina Iqbal, Fatima Jafri, Iqbal Azam and Wasim Jafri
    Citation: BMC Research Notes 2012 5:446
  13. ITN use is generally poor in Nigeria among all categories of people. Although use of ITNs has been shown to reduce malarial morbidity and mortality, this measure needs to be supported by an adequate healthcare...

    Authors: Olorunfemi E Amoran, Kehinde O Fatugase, Olubunmi M Fatugase and Kabir O Alausa
    Citation: BMC Research Notes 2012 5:444
  14. GPs increasingly deal with multiple health problems of their older patients. They have to apply a hierarchical management approach that considers priorities to balance competing needs for treatment. Yet, the p...

    Authors: Ulrike Junius-Walker, Jennifer Wrede, Tanja Schleef, Heike Diederichs-Egidi, Birgitt Wiese, Eva Hummers-Pradier and Marie-Luise Dierks
    Citation: BMC Research Notes 2012 5:443
  15. Health Technology Assessment (HTA) information, and in particular cost-effectiveness data is needed to guide decisions, preferably already in early stages of technological development. However, at that moment ...

    Authors: Valesca P Retèl, Manuela A Joore, Sabine C Linn, Emiel JT Rutgers and Wim H van Harten
    Citation: BMC Research Notes 2012 5:442
  16. Under-recognition of depression is common in many countries. Education of medical staff, focusing on their attitudes towards depression, may be necessary to change their behavior and enhance recognition of dep...

    Authors: Tsuyuka Ohtsuki, Manami Kodaka, Rumi Sakai, Fuminobu Ishikura, Yoichiro Watanabe, Anthony Mann, Mark Haddad, Mitsuhiko Yamada and Masatoshi Inagaki
    Citation: BMC Research Notes 2012 5:441
  17. Naltrexone has been proven to be an effective treatment option for the treatment of alcohol dependency. In this article we introduce a reliable and simple method developed for the simultaneous determination of...

    Authors: Pekka Heinälä, Tuuli Lahti, David Sinclair, Kari Ariniemi, Pirjo Lillsunde and Hannu Alho
    Citation: BMC Research Notes 2012 5:439
  18. Many autoimmune diseases are associated with variants of HLA genes such as those encoding the MHC complex. This correlation is not absolute, but may help in understanding of the molecular mechanism of disease....

    Authors: Lilija Kovalchuka, Jelena Eglite, Irina Lucenko, Mara Zalite, Ludmila Viksna and Angelika Krumiņa
    Citation: BMC Research Notes 2012 5:438
  19. Simultaneous use of cell-permeant and impermeant fluorescent nuclear dyes is a common method to study cell viability and cell death progression. Although these assays are usually conducted as end-point studies...

    Authors: Kyle S Hubbard, Ian M Gut, Stephen M Scheeler, Megan E Lyman and Patrick M McNutt
    Citation: BMC Research Notes 2012 5:437
  20. Breast carcinoma is known as a heterogeneous disease because gene expression analyses identify several subtypes and the molecular profiles are prognostic and predictive for patients. Our aim, in this study, is...

    Authors: Sanae Bennis, Fouad Abbass, Yousra Akasbi, Kaoutar Znati, Khalid Amrani Joutei, Omar El Mesbahi and Afaf Amarti
    Citation: BMC Research Notes 2012 5:436
  21. Duchenne muscular dystrophy (DMD) is a sex-linked inherited muscle disease characterized by a progressive loss in muscle strength and respiratory muscle involvement. After 12 years of age, lung function declin...

    Authors: Darlene L Machado, Elaine C Silva, Maria B D Resende, Celso R F Carvalho, Edmar Zanoteli and Umbertina C Reed
    Citation: BMC Research Notes 2012 5:435
  22. Insight in parental energy balance-related behaviours, their determinants and parenting practices are important to inform childhood obesity prevention. Therefore, reliable and valid tools to measure these vari...

    Authors: Amika S Singh, Mai JM Chinapaw, Léonie Uijtdewilligen, Froydis N Vik, Wendy van Lippevelde, Juan M Fernández-Alvira, Sarolta Stomfai, Yannis Manios, Maria van der Sluijs, Caroline Terwee and Johannes Brug
    Citation: BMC Research Notes 2012 5:434
  23. Gallstones are relatively rare in children. At-risk populations include patients suffering from hemolysis syndromes. Regardless of etiology, these patients usually will present with postprandial abdominal pain...

    Authors: Erik R Barthel, James R Pierce, Osnat Zmora, Susan R Harlan, Sudha Russell and Cathy Shin
    Citation: BMC Research Notes 2012 5:433
  24. Transposable elements (TEs) make up a large part of eukaryotic genomes. Due to their repetitive nature and to the fact that they harbour regulatory signals, TEs can be responsible for chromosomal rearrangement...

    Authors: Margarida Rocheta, Luísa Carvalho, Wanda Viegas and Leonor Morais-Cecílio
    Citation: BMC Research Notes 2012 5:432
  25. Teaching evidence-based medicine (EBM) should be evaluated and guided by evidence of its own effectiveness. However, no data are available on adoption of EBM by Syrian undergraduate, postgraduate, or practicin...

    Authors: Fares Alahdab, Belal Firwana, Rim Hasan, Mohamad Bassam Sonbol, Munes Fares, Iyad Alnahhas, Ammar Sabouni and Mazen Ferwana
    Citation: BMC Research Notes 2012 5:431
  26. The bacterium Staphylococcus aureus constitutes one of the most important causes of nosocomial infections. One out of every three individuals naturally carries S. aureus in their anterior nares, and nasal carriag...

    Authors: Georges C Frech, Denton Munns, Robert D Jenison and Brian J Hicke
    Citation: BMC Research Notes 2012 5:430
  27. Subspecies B1 human adenoviruses (HAdV-B1) are prevalent respiratory pathogens. Compared to their species C (HAdV-C) counterparts, relatively little work has been devoted to the characterization of their uniqu...

    Authors: Kathryn M Frietze, Samuel K Campos and Adriana E Kajon
    Citation: BMC Research Notes 2012 5:429
  28. Downstream applications in metabolomics, as well as mathematical modelling, require data in a quantitative format, which may also necessitate the automated and simultaneous quantification of numerous metabolit...

    Authors: Sergio Fructuoso, Ángel Sevilla, Cristina Bernal, Ana Belén Lozano, José Luis Iborra and Manuel Cánovas
    Citation: BMC Research Notes 2012 5:428
  29. Hawthorn is the common name of all plant species in the genus Crataegus, which belongs to the Rosaceae family. Crataegus are considered useful medicinal plants because of their high content of proanthocyanidins (...

    Authors: Afnan Said Zuiter, Jammal Sawwan and Ayed Al Abdallat
    Citation: BMC Research Notes 2012 5:427
  30. Secondary radiation-induced cancers are rare but well-documented as long-term side effects of radiation in large populations of breast cancer survivors. Multiple neoplasms are rare. We report a case of esophag...

    Authors: Soundouss Raissouni, Ferdaous Raissouni, Ghizlane Rais, Meryem Aitelhaj, Siham Lkhoyaali, Rachida Latib, Amina Mohtaram, Fadoua Rais, Hind Mrabti, Nawal Kabbaj, Naima Amrani and Hassan Errihani
    Citation: BMC Research Notes 2012 5:426
  31. The ATP-binding cassette transporter ABCC6 gene is located on chromosome 16 between its two pseudogenes (ABCC6P1 and ABCC6P2). Previously, we have shown that ABCC6P1 is transcribed and affects ABCC6 at the transc...

    Authors: Marianne K Kringen, Camilla Stormo, Runa M Grimholt, Jens P Berg and Armin P Piehler
    Citation: BMC Research Notes 2012 5:425
  32. Opinion leaders are often local individuals with high credibility who can influence other people. Robust effects using opinion leaders in diffusing innovations have been shown in several randomized controlled ...

    Authors: Karin Guldbrandsson, Monica K Nordvik and Sven Bremberg
    Citation: BMC Research Notes 2012 5:424
  33. Plating methods are still the golden standard in microbiology; however, some studies have shown that these techniques can underestimate the microbial concentrations and diversity. A nutrient shock is one of th...

    Authors: Nuno F Azevedo, Sofia M Bragança, Lúcia C Simões, Laura Cerqueira, Carina Almeida, Charles W Keevil and Maria J Vieira
    Citation: BMC Research Notes 2012 5:422
  34. Despite clear emphasis through the Millennium Development Goals, the problem of high maternal mortality persists especially within low and middle income countries. Various studies report remarkably high matern...

    Authors: Ekechi Okereke, Babatunde Ahonsi, Jamilu Tukur, Salisu Mohammed Ishaku and Ayodeji Babatunde Oginni
    Citation: BMC Research Notes 2012 5:421
  35. There is a circadian and circaseptal (weekly) variation in the onset of acute coronary syndrome (ACS). The aim of this study was to elucidate whether the likelihood of ACS among emergency department (ED) chest...

    Authors: Ulf Ekelund, Mahin Akbarzadeh, Ardavan Khoshnood, Jonas Björk and Mattias Ohlsson
    Citation: BMC Research Notes 2012 5:420
  36. Imaging Mass Spectrometry (IMS) provides a means to measure the spatial distribution of biochemical features on the surface of a sectioned tissue sample. IMS datasets are typically huge and visualisation and s...

    Authors: Glenn Stone, David Clifford, Johan OR Gustafsson, Shaun R McColl and Peter Hoffmann
    Citation: BMC Research Notes 2012 5:419
  37. This pilot study (ClinicalTrials.gov ID: NCT01507701) assessed the feasibility and safety of clonidine in adolescent chronic fatigue syndrome (CFS). Specifically, we assessed clonidine dosage in relation to a)...

    Authors: Even Fagermoen, Dag Sulheim, Anette Winger, Anders M Andersen, Nils Tore Vethe, J Philip Saul, Erik Thaulow and Vegard Bruun Wyller
    Citation: BMC Research Notes 2012 5:418
  38. Rating scales are valuable tools in suicide research and can also be useful supplements to the clinical interview in suicide risk assessments. This study describes the psychometric properties of a Norwegian la...

    Authors: Bjørn Odd Koldsland, Lars Mehlum, Liv Solrunn Mellesdal, Fredrik A Walby and Lien M Diep
    Citation: BMC Research Notes 2012 5:417
  39. Diagnosis of amoebic liver abscess (ALA) in patients on anti-amoebic drugs is difficult. There is scanty data on this issue using Entamoeba histolytica (E. histolytica) lectin antigen and polymerase chain reactio...

    Authors: Virendra Jaiswal, Ujjala Ghoshal, Sanjay S Baijal, Balraj Mittal, Tapan N Dhole and Uday C Ghoshal
    Citation: BMC Research Notes 2012 5:416
  40. One third of the world’s population is thought to have latent tuberculosis infection (LTBI) with the potential for subsequent reactivation of disease. To better characterize this important population, studies ...

    Authors: Alemnew F Dagnew, Jemal Hussein, Markos Abebe, Martha Zewdie, Adane Mihret, Ahmed Bedru, Menberework Chanyalew, Lawrence Yamuah, Girmay Medhin, Peter Bang, T Mark Doherty, Asrat Hailu and Abraham Aseffa
    Citation: BMC Research Notes 2012 5:415
  41. Recent studies have identified several single-nucleotide polymorphisms (SNPs) associated with the risk of breast cancer and parity and age at first childbirth are well established and important risk factors fo...

    Authors: Salma Butt, Sophia Harlid, Signe Borgquist, Malin Ivarsson, Göran Landberg, Joakim Dillner, Joyce Carlson and Jonas Manjer
    Citation: BMC Research Notes 2012 5:414
  42. Pharmacies are venues in which patients seek out products and professional advice in order to improve overall health. However, many pharmacies in the United States continue to sell tobacco products, which are ...

    Authors: Danielle M Smith, Andrew J Hyland, Cheryl Rivard, Edward M Bednarczyk, Peter M Brody and James R Marshall
    Citation: BMC Research Notes 2012 5:413
  43. Maternal cardiovascular and pulmonary events during labor and delivery may result in adverse maternal and fetal outcome. Potential etiologies include primary cardiac events, pulmonary embolism, eclampsia, mate...

    Authors: Michelle A O Kinney, Carl H Rose, Kyle D Traynor, Eric Deutsch, Hafsa U Memon, Staci Tanouye, Katherine W Arendt and James R Hebl
    Citation: BMC Research Notes 2012 5:412
  44. Evidence for the association between Human immunodeficiency virus infection and cervical cancer has been contrasting, with some studies reporting increased risk of cervical cancer among HIV positive women whil...

    Authors: Dismas Matovelo, Moke Magoma, Peter Rambau, Anthony Massinde and Nestory Masalu
    Citation: BMC Research Notes 2012 5:406

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