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  1. Myosin II-dependent contraction of the cytokinetic ring and primary septum formation by chitin synthase II are interdependent processes during cytokinesis in Saccharomyces cerevisiae. Hence, null mutants of myosi...

    Authors: José F Rodríguez-Quiñones and José R Rodríguez-Medina

    Citation: BMC Research Notes 2009 2:87

    Content type: Short Report

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  2. The murine ghrelin gene (Ghrl), originally sequenced from stomach tissue, contains five exons and a single transcription start site in a short, 19 bp first exon (exon 0). We recently isolated several novel first ...

    Authors: Inge Seim, Shea L Carter, Adrian C Herington and Lisa K Chopin

    Citation: BMC Research Notes 2009 2:85

    Content type: Short Report

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  3. Marbling defined by the amount and distribution of intramuscular fat is an economically important trait of beef cattle in Japan. We have recently reported that single nucleotide polymorphisms (SNPs) in the endoth...

    Authors: Takahisa Yamada, Seiki Sasaki, Shin Sukegawa, Sachiyo Yoshioka, Youichi Takahagi, Mitsuo Morita, Hiroshi Murakami, Fumiki Morimatsu, Tatsuo Fujita, Takeshi Miyake and Yoshiyuki Sasaki

    Citation: BMC Research Notes 2009 2:78

    Content type: Short Report

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  4. The aim of this study was to develop a simple organ score derived from the Critical Care Minimum Data Set (CCMDS) to compare with the Sequential Organ Failure Assessment (SOFA) score, a previously validated sc...

    Authors: Tim W Felton, Rebecca Sander, Mo Al-Aloul, Paul Dark and Andrew M Bentley

    Citation: BMC Research Notes 2009 2:77

    Content type: Short Report

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  5. This study investigated the nosocomial blood stream infection (BSI) in the adult ICUs in Assiut university hospitals to evaluate the rate of infection in different ICUs, causative microorganisms, antimicrobial...

    Authors: Shaaban H Ahmed, Enas A Daef, Mohammed S Badary, Mohammed A Mahmoud and Alaa A Abd-Elsayed

    Citation: BMC Research Notes 2009 2:76

    Content type: Short Report

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  6. Attention deficit hyperactivity disorder (ADHD) is a common, childhood-onset neurodevelopmental disorder that is more frequent in males than females. Several genes on the X chromosome have been studied as cand...

    Authors: Xiaohui Xu, Keeley Brookes, Bo Sun, Nicholas Ilott and Philip Asherson

    Citation: BMC Research Notes 2009 2:71

    Content type: Short Report

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  7. Apart from simple steatosis, the non-alcoholic steatohepatitis (NASH) can progress into liver fibrosis and cirrhosis. To date, however, no widely accepted therapeutic modalities have been established against N...

    Authors: Hitoshi Yoshiji, Ryuichi Noguchi, Yasuhide Ikenaka, Tadashi Namisaki, Mitsuteru Kitade, Kosuke Kaji, Yusaku Shirai, Junichi Yoshii, Koji Yanase, Masaharu Yamazaki, Tatsuhiro Tsujimoto, Hideto Kawaratani, Takemi Akahane, Yosuke Aihara and Hiroshi Fukui

    Citation: BMC Research Notes 2009 2:70

    Content type: Short Report

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  8. It can be seen from the available mollusk mitogenomes that the family Pectinidae exhibits the most variation in genome organization. In this study, comparative mitogenomic analyses were performed for three sca...

    Authors: Xiangyun Wu, Xiaodong Xu, Ziniu Yu and Xiaoyu Kong

    Citation: BMC Research Notes 2009 2:69

    Content type: Short Report

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  9. Oxygenases belong to the oxidoreductive group of enzymes (E.C. Class 1), which oxidize the substrates by transferring oxygen from molecular oxygen (O2) and utilize FAD/NADH/NADPH as the co-substrate. Oxygenases c...

    Authors: Pankaj K Arora, Manish Kumar, Archana Chauhan, Gajendra PS Raghava and Rakesh K Jain

    Citation: BMC Research Notes 2009 2:67

    Content type: Data Note

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  10. Activating mutations in the PIK3CA gene have been identified in a variety of human malignancies and are commonly detected in hotspot codons located in the helical and kinase domains in exons 9 and 20. Existing me...

    Authors: Carolyn D Hurst, Tahlita CM Zuiverloon, Christian Hafner, Ellen C Zwarthoff and Margaret A Knowles

    Citation: BMC Research Notes 2009 2:66

    Content type: Technical Note

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  11. Cell-specific expression of a subset of Enhancer of split (E(spl)-C) genes in proneural clusters is mediated by synergistic interactions between bHLH A (b asic H elix-L oop-H elix A ctivator) and Notch-signalling...

    Authors: John W Cave, Li Xia and Michael A Caudy

    Citation: BMC Research Notes 2009 2:65

    Content type: Short Report

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  12. Baculovirus expression vector system (BEVS) has become a standard in recombinant protein production and virus-like particle preparation for numerous applications.

    Authors: Hanna-Riikka Kärkkäinen, Hanna P Lesch, Antti I Määttä, Pyry I Toivanen, Anssi J Mähönen, Miia M Roschier, Kari J Airenne, Olli H Laitinen and Seppo Ylä-Herttuala

    Citation: BMC Research Notes 2009 2:63

    Content type: Technical Note

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  13. The purpose of this report is to assess the safety and efficacy of single lower pole access for multiple and branched renal calculi. A prospective non randomized clinical study included 26 patients with comple...

    Authors: Mahmoud M Shalaby, Medhat A Abdalla, Hassan A Aboul-Ella, Abdel-Monem A El-haggagy and Alaa A Abd-Elsayed

    Citation: BMC Research Notes 2009 2:62

    Content type: Short Report

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  14. Dermatophytes are a group of closely related keratinophilic fungi that can invade keratinized humans and animals tissues such as skin, hair and nails causing dermatophytosis. They are an important cause of sup...

    Authors: Jaya Garg, Ragini Tilak, Atul Garg, Pradyot Prakash, Anil Kumar Gulati and Gopal Nath

    Citation: BMC Research Notes 2009 2:60

    Content type: Short Report

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  15. The Runt DNA binding domain (Runx) defines a metazoan family of sequence-specific transcription factors with essential roles in animal ontogeny and stem cell based development. Depending on cis-regulatory context...

    Authors: Anthony J Robertson, Claire Larroux, Bernard M Degnan and James A Coffman

    Citation: BMC Research Notes 2009 2:59

    Content type: Short Report

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  16. Fluorescent proteins such as GFP (Green Fluorescent Protein) and DsRED (Discosoma sp.Red Fluorescent Protein) are often used as reporter molecules for transgene expression in Drosophila and other species. We h...

    Authors: Dhruv Grover, Junsheng Yang, Daniel Ford, Simon Tavaré and John Tower

    Citation: BMC Research Notes 2009 2:58

    Content type: Short Report

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  17. We analyzed the use of RefSNP (rs) numbers to identify genetic variants in abstracts of human genetic association studies published from 2001 through 2007. The proportion of abstracts reporting rs numbers incr...

    Authors: Wei Yu, Renée Ned, Anja Wulf, Tiebin Liu, Muin J Khoury and Marta Gwinn

    Citation: BMC Research Notes 2009 2:56

    Content type: Correspondence

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  18. Asthma is a complex phenotype that is influenced by both genetic and environmental factors. Genome-wide linkage and association studies have been performed to identify susceptibility genes for asthma. These st...

    Authors: Yoshiko Imada, Masaya Fujimoto, Kenji Hirata, Tomomitsu Hirota, Yoichi Suzuki, Hirohisa Saito, Kenji Matsumoto, Akira Akazawa, Toshio Katsunuma, Shigemi Yoshihara, Motohiro Ebisawa, Masanao Shibasaki, Tadao Arinami, Mayumi Tamari and Emiko Noguchi

    Citation: BMC Research Notes 2009 2:54

    Content type: Short Report

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  19. The nucleotide-binding oligomerization domain containing 1 (NOD1) gene encodes a pattern recognition receptor that senses pathogens, leading to downstream responses characteristic of innate immunity. We investiga...

    Authors: Claudia Huebner, Lynnette R Ferguson, Dug Yeo Han, Martin Philpott, Murray L Barclay, Richard B Gearry, Alan McCulloch, Pieter S Demmers and Brian L Browning

    Citation: BMC Research Notes 2009 2:52

    Content type: Short Report

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  20. Free-living amoebae serve as a natural reservoir for some bacteria that have evolved into «amoeba-resistant» bacteria. Among these, some are strictly intra-amoebal, such as Candidatus "Protochlamydia amoebophila"...

    Authors: Claire Moliner, Didier Raoult and Pierre-Edouard Fournier

    Citation: BMC Research Notes 2009 2:51

    Content type: Short Report

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  21. Antimicrobial resistance is fast becoming a global concern with rapid increases in multidrug-resistant Gram negative organisms. The prevalence of extended spectrum beta-lactamase (ESBL)-producing clinical isol...

    Authors: Stephen E Mshana, Erasmus Kamugisha, Mariam Mirambo, Trinad Chakraborty and Eligius F Lyamuya

    Citation: BMC Research Notes 2009 2:49

    Content type: Short Report

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  22. Whole genome amplification (WGA) is a practical solution to eliminate molecular analysis limitations associated with genomic DNA (gDNA) quantity. Different methods have been developed to amplify the whole geno...

    Authors: Osama Alsmadi, Fadi Alkayal, Dorota Monies and Brian F Meyer

    Citation: BMC Research Notes 2009 2:48

    Content type: Short Report

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  23. The protozoan parasite, Trypanosoma brucei, is spread by the tsetse fly and causes Human African Trypanosomiasis. Its cell cycle is complex and not fully understood at the molecular level. The T. brucei genome co...

    Authors: Séverine Monnerat, Caroline Clucas, Elaine Brown, Jeremy C Mottram and Tansy C Hammarton

    Citation: BMC Research Notes 2009 2:46

    Content type: Short Report

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  24. Anti-cyclic citrullinated peptides (anti-CCP) are highly specific diagnostic and prognostic markers for rheumatoid arthritis (RA). They have been also found in psoriatic arthritis (PsA), with controversies as ...

    Authors: Nermeen SA Abdel Fattah, Hanan E Hassan, Zenab A Galal and El Sayed E El Okda

    Citation: BMC Research Notes 2009 2:44

    Content type: Short Report

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  25. Warfarin is an oral anticoagulant (OAT) that needs active management to ensure therapeutic range. Initial management is often carried out as an inpatient, though not requiring inpatient facilities. This mismat...

    Authors: Dónall Forde, Mortimer B O'Connor and Oonagh Gilligan

    Citation: BMC Research Notes 2009 2:41

    Content type: Short Report

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  26. Nemaline myopathy is a neuromuscular disorder characterized by the presence of nemaline bodies in patient muscles. 20% of the cases are associated with α-skeletal muscle actin mutations. We previously showed t...

    Authors: Drieke Vandamme, Ellen Lambert, Davy Waterschoot, Davina Tondeleir, Joël Vandekerckhove, Laura M Machesky, Bruno Constantin, Heidi Rommelaere and Christophe Ampe

    Citation: BMC Research Notes 2009 2:40

    Content type: Short Report

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  27. Currently one of the largest online repositories for human and mouse stem cell gene expression data, StemBase was first designed as a simple web-interface to DNA microarray data generated by the Canadian Stem ...

    Authors: Reatha Sandie, Gareth A Palidwor, Matthew R Huska, Christopher J Porter, Paul M Krzyzanowski, Enrique M Muro, Carolina Perez-Iratxeta and Miguel A Andrade-Navarro

    Citation: BMC Research Notes 2009 2:39

    Content type: Technical Note

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  28. Achromobacter sp. AO22 (formerly Alcaligenes sp. AO22), a bacterial strain isolated from a lead-contaminated industrial site in Australia, was previously found to be resistant to moderate to high levels of mercur...

    Authors: Shee Ping Ng, Belinda Davis, Enzo A Palombo and Mrinal Bhave

    Citation: BMC Research Notes 2009 2:38

    Content type: Short Report

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  29. Citrus Huanglongbing (HLB) is one of the most devastating diseases on citrus and is associated with Candidatus Liberibacter spp.. The pathogens are phloem limited and have not been cultured in vitro. The current ...

    Authors: Jeong-soon Kim and Nian Wang

    Citation: BMC Research Notes 2009 2:37

    Content type: Short Report

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  30. Macrophage migration inhibitory factor (MIF) is a multifunctional cytokine implicated in the pathogenesis of a number of human diseases including inflammatory neurological diseases. Its role in the pathogenesi...

    Authors: Vidhan Jain, Shannon McClintock, Avinash C Nagpal, Aditya P Dash, Jonathan K Stiles, Venkatachalam Udhayakumar, Neeru Singh and Naomi W Lucchi

    Citation: BMC Research Notes 2009 2:36

    Content type: Short Report

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  31. Tetanus is an infectious disease caused by the contamination of wounds from bacteria that live in soil. The tetanus mortality rate remains high in developing countries affected by natural disasters. Whether th...

    Authors: Agung Budi Sutiono, Andri Qiantori, Hirohiko Suwa and Toshizumi Ohta

    Citation: BMC Research Notes 2009 2:34

    Content type: Short Report

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  32. Sequence information on the 16S-23S rDNA internal spacer region (ISR) exhibits a large degree of sequence and length variation at both the genus and species levels. A primer pair for the amplification of 16S-2...

    Authors: Akihiro Tazumi, Shinji Ono, Tsuyoshi Sekizuka, John E Moore, B Cherie Millar and Motoo Matsuda

    Citation: BMC Research Notes 2009 2:33

    Content type: Short Report

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