Gulan G, Ravlic-Gulan J, Strbo N, Sotosek V, Nemec B, Matovinovic D, et al, et al: Systemic and local expression of perforin in lymphocyte subsets in acute and chronic rheumatoid arthritis. J Rheumatol. 2003, 30: 660-670.
CAS
PubMed
Google Scholar
Kaplan MJ, Lu Q, Wu A, Attwood J, Richardson B: Demethylation of promoter regulatory elements contributes to perforin overexpression in CD4+ lupus T cells. J Immunol. 2004, 172: 3652-3661.
Article
CAS
PubMed
Google Scholar
Kastelan M, Prpic ML, Gruber F, Zamolo G, Zauhar G, Coklo M, et al, et al: Perforin expression is upregulated in the epidermis of psoriatic lesions. Br J Dermatol. 2004, 151: 831-836. 10.1111/j.1365-2133.2004.06168.x.
Article
CAS
PubMed
Google Scholar
Li M, Yang Q, Zhang Y: Effects of CD134 monoclonal antibody on hemolysis activities and expression of perforin in peripheral blood mononuclear cells of systemic lupus erythematosus patients. Hybridoma (Larchmt). 2007, 26: 191-200. 10.1089/hyb.2007.010.
Article
CAS
Google Scholar
Lu Q, Wu A, Ray D, Deng C, Attwood J, Hanash S, et al, et al: DNA methylation and chromatin structure regulate T cell perforin gene expression. J Immunol. 2003, 170: 5124-5132.
Article
CAS
PubMed
Google Scholar
Maher KJ, Klimas NG, Fletcher MA: Chronic fatigue syndrome is associated with diminished intracellular perforin. Clin Exp Immunol. 2005, 142: 505-511.
PubMed Central
CAS
PubMed
Google Scholar
Skarpa I, Rubesa G, Moro L, Manestar D, Petrovecki M, Rukavina D: Changes of cytolytic cells and perforin expression in patients with posttraumatic stress disorder. Croat Med J. 2001, 42: 551-555.
CAS
PubMed
Google Scholar
Steinau M, Unger ER, Vernon SD, Jones JF, Rajeevan MS: Differential-display PCR of peripheral blood for biomarker discovery in chronic fatigue syndrome. J Mol Med. 2004, 82: 750-755. 10.1007/s00109-004-0586-4.
Article
CAS
PubMed
Google Scholar
Trapani JA, Voskoboinik I: The complex issue of regulating perforin expression. Trends Immunol. 2007, 28: 243-245. 10.1016/j.it.2007.04.003.
Article
CAS
PubMed
Google Scholar
Rajeevan MS, Swan DC, Duncan K, Lee DR, Limor JR, Unger ER: Quantitation of site-specific HPV 16 DNA methylation by pyrosequencing. J Virol Methods. 2006, 138: 170-176. 10.1016/j.jviromet.2006.08.012.
Article
CAS
PubMed
Google Scholar
Singal R, Grimes SR: Microsoft Word macro for analysis of cytosine methylation by the bisulfite deamination reaction. Biotechniques. 2001, 30: 116-120.
CAS
PubMed
Google Scholar
Shen L, Guo Y, Chen X, Ahmed S, Issa JP: Optimizing annealing temperature overcomes bias in bisulfite PCR methylation analysis. Biotechniques. 2007, 42: 48-10.2144/000112312. 50, 52.
Article
CAS
PubMed
Google Scholar
Colella S, Shen L, Baggerly KA, Issa JP, Krahe R: Sensitive and quantitative universal Pyrosequencing methylation analysis of CpG sites. Biotechniques. 2003, 35: 146-150.
CAS
PubMed
Google Scholar
Lichtenheld MG, Podack ER: Structure of the human perforin gene. A simple gene organization with interesting potential regulatory sequences. J Immunol. 1989, 143: 4267-4274.
CAS
PubMed
Google Scholar
Zhang J, Scordi I, Smyth MJ, Lichtenheld MG: Interleukin 2 receptor signaling regulates the perforin gene through signal transducer and activator of transcription (Stat)5 activation of two enhancers. J Exp Med. 1999, 190: 1297-1308. 10.1084/jem.190.9.1297.
Article
PubMed Central
CAS
PubMed
Google Scholar
Gharizadeh B, Akhras M, Nourizad N, Ghaderi M, Yasuda K, Nyren P, et al, et al: Methodological improvements of pyrosequencing technology. J Biotechnol. 2006, 124: 504-511. 10.1016/j.jbiotec.2006.01.025.
Article
PubMed Central
CAS
PubMed
Google Scholar
Mashayekhi F, Ronaghi M: Analysis of read length limiting factors in Pyrosequencing chemistry. Anal Biochem. 2007, 363: 275-287. 10.1016/j.ab.2007.02.002.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ogino S, Kawasaki T, Brahmandam M, Cantor M, Kirkner GJ, Spiegelman D, et al, et al: Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis. J Mol Diagn. 2006, 8: 209-217. 10.2353/jmoldx.2006.050135.
Article
PubMed Central
CAS
PubMed
Google Scholar
Dupont JM, Tost J, Jammes H, Gut IG: De novo quantitative bisulfite sequencing using the pyrosequencing technology. Anal Biochem. 2004, 333: 119-127. 10.1016/j.ab.2004.05.007.
Article
CAS
PubMed
Google Scholar
Mikeska T, Bock C, El-Maarri O, Hubner A, Ehrentraut D, Schramm J, et al, et al: Optimization of quantitative MGMT promoter methylation analysis using pyrosequencing and combined bisulfite restriction analysis. J Mol Diagn. 2007, 9: 368-381. 10.2353/jmoldx.2007.060167.
Article
PubMed Central
CAS
PubMed
Google Scholar
Tost J, Gut IG: DNA methylation analysis by pyrosequencing. Nat Protoc. 2007, 2: 2265-2275. 10.1038/nprot.2007.314.
Article
CAS
PubMed
Google Scholar
Irizarry RA, Ladd-Acosta C, Carvalho B, Wu H, Brandenburg SA, Jeddeloh JA, et al, et al: Comprehensive high-throughput arrays for relative methylation (CHARM). Genome Res. 2008, 18: 780-790. 10.1101/gr.7301508.
Article
PubMed Central
CAS
PubMed
Google Scholar
White HE, Durston VJ, Harvey JF, Cross NC: Quantitative analysis of SNRPN(correction of SRNPN) gene methylation by pyrosequencing as a diagnostic test for Prader-Willi syndrome and Angelman syndrome. Clin Chem. 2006, 52: 1005-1013. 10.1373/clinchem.2005.065086.
Article
CAS
PubMed
Google Scholar
Uhlmann K, Brinckmann A, Toliat MR, Ritter H, Nurnberg P: Evaluation of a potential epigenetic biomarker by quantitative methyl-single nucleotide polymorphism analysis. Electrophoresis. 2002, 23: 4072-4079. 10.1002/elps.200290023.
Article
CAS
PubMed
Google Scholar