Jemal A, Siegel R, Xu J, Ward E: Cancer statistics, 2010. CA Cancer J Clin. 2010, 60: 277-300. 10.3322/caac.20073.
Article
PubMed
Google Scholar
Burbee DG, Forgacs E, Zochbauer-Muller S, et al, et al: Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression. J Natl Cancer Inst. 2001, 93: 691-699. 10.1093/jnci/93.9.691.
Article
PubMed
CAS
PubMed Central
Google Scholar
Dammann R, Takahashi T, Pfeifer G: The CpG island of the novel tumor suppressor gene RASSF1A is intensely methylated in primary small cell lung carcinoma. Oncogene. 2001, 20: 3563-3567. 10.1038/sj.onc.1204469.
Article
PubMed
CAS
Google Scholar
Agathanggelou A, Honorio S, Macartney DP, et al, et al: Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast, and ovarian tumors. Oncogene. 2001, 20: 1509-1518. 10.1038/sj.onc.1204175.
Article
PubMed
CAS
Google Scholar
Agathanggelou A, Bieche I, Ahmed-Choudhury J, et al, et al: Identification of novel gene expression targets for Ras association domain family 1(RASSF1A) tumor suppressor gene in non-small cell lung cancer and neuroblastoma. Cancer Res. 2003, 63: 5344-5351.
PubMed
CAS
PubMed Central
Google Scholar
Dammann R, Li C, Yoon JH, Chin PL, Bates S, Pfeifer GP: Epigenetic inactivation of a RAS association domain family protein from the lung tumor suppressor locus 3p21.3. Nat Genet. 2000, 25: 315-319. 10.1038/77083.
Article
PubMed
CAS
Google Scholar
Dreijerink K, Braga E, Kuzmin I, et al, et al: The candidate tumor suppressor gene, RASS1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis. Proc Natl Acad Sci USA. 2001, 98: 7504-7509. 10.1073/pnas.131216298.
Article
PubMed
CAS
PubMed Central
Google Scholar
Tommasi S, Dammann R, Zhang Z, et al, et al: Tumor Susceptibility of RASSF1A Knockout Mice. Cancer Res. 2005, 65: 92-98.
PubMed
CAS
Google Scholar
Liu L, Yoon JH, Dammann R, Pfeifer GP: Frequent hypermethylation of the RASSF1A gene in prostate cancer. Oncogene. 2002, 21: 6835-6840. 10.1038/sj.onc.1205814.
Article
PubMed
CAS
Google Scholar
Vos MD, Ellis CA, Bell A, Birrer MJ, Clark GJ: Ras uses the novel tumor suppressor RASSF1 as an effector to mediate apoptosis. J Biol Chem. 2000, 275: 35669-35672. 10.1074/jbc.C000463200.
Article
PubMed
CAS
Google Scholar
Li J, Wang F, Protopopov A, et al, et al: Inactivation of RASSF1C during in vivo tumor growth identifies it as a tumor suppressor gene. Oncogene. 2004, 23: 5941-5949. 10.1038/sj.onc.1207789.
Article
PubMed
CAS
Google Scholar
Vos MD, Martinez A, Elam C, et al, et al: A role for the RASSF1A tumor suppressor in the regulation of tubulin polymerization and genomic stability. Cancer Res. 2004, 64: 4244-4250. 10.1158/0008-5472.CAN-04-0339.
Article
PubMed
CAS
Google Scholar
Kitagawa D, Kajiho H, Negishi T, et al, et al: Release of RASSF1C from the nucleus by Daxx degradation links DNA damage and SAPK/JNK activation. EMBO J. 2006, 25: 3286-3297. 10.1038/sj.emboj.7601212.
Article
PubMed
CAS
PubMed Central
Google Scholar
Reeves ME, Baldwin SW, Baldwin ML, Chen ST, Moretz JM, Aragon RJ, Li X, Strong DD, Mohan S, Amaar YG: Ras-association domain family 1C protein promotes breast cancer cell migration and attenuates apoptosis. BMC Cancer. 2010 Oct 18, 10: 562-10.1186/1471-2407-10-562.
Article
PubMed
CAS
PubMed Central
Google Scholar
Amaar YG, Minera MG, Hatran LK, Strong DD, Mohan S, Reeves ME: Ras association domain family 1C protein stimulates human lung cancer cell proliferation. Am J Physiol Lung Cell Mol Physiol. 2006, 291: 1185-1190. 10.1152/ajplung.00072.2006.
Article
Google Scholar
Estrabaud E, Lassot I, Blot G, et al, et al: RASSF1C, an isoform of the tumor suppressor RASSF1A, promotes the accumulation of beta-catenin by interacting with betaTrCP. Cancer Res. 2007, 67: 1054-1061. 10.1158/0008-5472.CAN-06-2530.
Article
PubMed
CAS
Google Scholar
Amaar YG, Baylink DJ, Mohan S: RAS association domain family protein, RASSF1C, is an IGFBP-5 binding partner and a potential regulator of osteoblast cell proliferation. J Bone Miner Res. 2005, 20: 1430-1439. 10.1359/JBMR.050311.
Article
PubMed
CAS
PubMed Central
Google Scholar
Amaar YG, Thompson G, Linkhart TA, Chen ST, Baylink DJ, Mohan S: Insulin-like growth factor binding protein 5 (IGFBP-5) interacts with a four and a half LIM protein 2 (FHL2). J Biol Chem. 2002, 277: 12053-12060. 10.1074/jbc.M110872200.
Article
PubMed
CAS
Google Scholar
Livak KJ, Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(−Delta Delta C (T)) Method. Methods. 2001, 25: 402-408. 10.1006/meth.2001.1262.
Article
PubMed
CAS
Google Scholar
Li C, Wong WH: Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection. Proc Natl Acad Sci USA. 2001, 98: 31-36. 10.1073/pnas.98.1.31.
Article
PubMed
CAS
PubMed Central
Google Scholar
Taubert H, Würl P, Greither T, Kappler M, Bache M, Bartel F, Kehlen A, Lautenschläger C, Harris LC, Kaushal D, Füssel S, Meye A, Böhnke A, Schmidt H, Holzhausen HJ, Hauptmann S: Stem cell-associated genes are extremely poor prognostic factors for soft-tissue sarcoma patients. Oncogene. 2007, 26: 7170-7174. 10.1038/sj.onc.1210530.
Article
PubMed
CAS
Google Scholar
Taubert H, Greither T, Kaushal D, Würl P, Bache M, Bartel F, Kehlen A, Lautenschläger C, Harris L, Kraemer K, Meye A, Kappler M, Schmidt H, Holzhausen HJ, Hauptmann S: Expression of the stem cell self-renewal gene Hiwi and risk of tumour-related death in patients with soft-tissue sarcoma. Oncogene. 2007, 26: 1098-1100. 10.1038/sj.onc.1209880.
Article
PubMed
CAS
Google Scholar
Liu X, Sun Y, Guo J, Ma H, Li J, Dong B, Jin G, Zhang J, Wu J, Meng L, Shou C: Expression of hiwi gene in human gastric cancer was associated with proliferation of cancer cells. Int J Cancer. 2006, 118: 1922-1929. 10.1002/ijc.21575.
Article
PubMed
CAS
Google Scholar
Grochola LF, Greither T, Taubert H, Möller P, Knippschild U, Udelnow A, Henne-Bruns D, Würl P: The stem cell-associated Hiwi gene in human adenocarcinoma of the pancreas: expression and risk of tumour-related death. Br J Cancer. 2008, 99: 1083-1088. 10.1038/sj.bjc.6604653.
Article
PubMed
CAS
PubMed Central
Google Scholar
Patel M, Lu L, Zander DS, Sreerama L, Coco D, Moreb JS: ALDH1A1 and ALDH3A1 expression in lung cancers: Correlation with histologic type and potential precursors. Lung Cancer. 2008, 59: 340-349. 10.1016/j.lungcan.2007.08.033.
Article
PubMed
Google Scholar
Sunaga N, Miyajima K, Suzuki M, et al, et al: Different roles for caveolin-1 in the development of non-small cell lung cancer versus small cell lung cancer. Cancer Res. 2004, 64: 4277-4285. 10.1158/0008-5472.CAN-03-3941.
Article
PubMed
CAS
Google Scholar
Kikuchi S, Yamada D, Fukami T, et al, et al: Promoter methylation of DAL-1/4.1B predicts poor prognosis in non-small cell lung cancer. Clin Cancer Res. 2005, 11: 2954-2961. 10.1158/1078-0432.CCR-04-2206.
Article
PubMed
CAS
Google Scholar
Ghaleb AM, Katz JP, Kaestner KH, Du JX, Yang VW: Krüppel-like factor 4 exhibits antiapoptotic activity following gamma-radiation-induced DNA damage. Oncogene. 2007, 26: 2365-2373. 10.1038/sj.onc.1210022.
Article
PubMed
CAS
PubMed Central
Google Scholar
Ura K, Obama K, Satoh S, Sakai Y, Nakamura Y, Furukawa Y: Enhanced RASGEF1A expression is involved in the growth and migration of intrahepatic cholangiocarcinoma. Clin Cancer Res. 2006, 12: 6611-6616. 10.1158/1078-0432.CCR-06-0783.
Article
PubMed
CAS
Google Scholar
Park YY, Kim SH, Kim YJ, et al, et al: Polo-like kinase 2 gene expression is regulated by the orphan nuclear receptor estrogen receptor-related receptor gamma (ERRgamma). Biochem Biophys Res Comm. 2007, 362: 107-113. 10.1016/j.bbrc.2007.07.170.
Article
PubMed
CAS
Google Scholar
Bunting KD: ABC transporters as phenotypic markers and functional regulators of stem cells. Stem Cells. 2002, 20: 11-20. 10.1002/stem.200011.
Article
PubMed
CAS
Google Scholar
Chow LS, Lam CW, Chan SY, et al, et al: Identification of RASSF1A modulated genes in nasopharyngeal carcinoma. Oncogene. 2006, 25: 310-316.
PubMed
CAS
Google Scholar
Kim CF, Jackson EL, Woolfenden AE, et al, et al: Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell. 2005, 121: 823-835. 10.1016/j.cell.2005.03.032.
Article
PubMed
CAS
Google Scholar
Ho MM, Ng AV, Lam S, Hung JY: Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells. Cancer Res. 2007, 67: 4827-4833. 10.1158/0008-5472.CAN-06-3557.
Article
PubMed
CAS
Google Scholar
Pelosi G, Fumagalli C, Trubia M, Sonzogni A, Rekhtman N, Maisonneuve P, Galetta D, Spaggiari L, Veronesi G, Scarpa A, Malpeli G, Viale G: Dual role of RASSF1 as a tumor suppressor and an oncogene in neuroendocrine tumors of the lung. Anticancer Res. 2010, 30: 4269-4281.
PubMed
CAS
Google Scholar
Malpeli G, Amato E, Dandrea M, Fumagalli C, Debattisti V, Boninsegna L, Pelosi G, Falconi M, Scarpa A: Methylation-associated down-regulation of RASSF1A and up-regulation of RASSF1C in pancreatic endocrine tumors. BMC Cancer. 2011, 11: 351-10.1186/1471-2407-11-351.
Article
PubMed
CAS
PubMed Central
Google Scholar