Buck L, Axel R. A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell. 1991;65:175–87.
Article
CAS
PubMed
Google Scholar
Niimura Y, Masatoshi N. Extensive gains and losses of olfactory receptor genes in mammalian evolution. PLoS ONE. 2007;2(8):e708.
Article
PubMed
PubMed Central
Google Scholar
Gu X, Karp PH, Brody SL, Pierce RA, Welsh MJ, Holtzman MJ, et al. Chemosensory functions for pulmonary neuroendocrine cells. Am J Respir Cell Mol Biol. 2014;50(3):637–46.
Article
PubMed
PubMed Central
Google Scholar
Li JJ, Tay HL, Plank M, Essilfie AT, Hansbro PM, Foster PS, et al. Activation of olfactory receptors on mouse pulmonary macrophages promotes monocyte chemotactic protein-1 production. PLoS ONE. 2013;8(11):e80148.
Article
PubMed
PubMed Central
Google Scholar
Pluznick JL, Protzko RJ, Gevorgyan H, Peterlin Z, Sipos A, Han J, et al. Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation. Proc Natl Acad Sci USA. 2013;110(11):4410–5.
Article
CAS
PubMed
PubMed Central
Google Scholar
Griffin CA, Kafadar KA, Pavlath GK. MOR23 promotes muscle regeneration and regulates cell adhesion and migration. Dev Cell. 2009;17:649–61.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kidd M, Modlin IM, Gustafsson BI, Drozdov I, Hauso O, Pfragner R. Luminal regulation of normal and neoplastic human EC cell serotonin release is mediated by bile salts, amines, tastants, and olfactants. Am J Physiol Gastrointest Liver Physiol. 2008;295(2):G260–72.
Article
CAS
PubMed
Google Scholar
Braun T, Voland P, Kunz L, Prinz C, Gratzl M. Enterochromaffin cells of the human gut: sensors for spices and odorants. Gastroenterology. 2007;132(5):1890–901.
Article
CAS
PubMed
Google Scholar
Fukuda N, Touhara K. Developmental expression patterns of testicular olfactory receptor genes during mouse spermatogenesis. Genes Cells. 2006;11(1):71–81.
Article
CAS
PubMed
Google Scholar
Spehr M, Schwane K, Heilmann S, Gisselmann G, Hummel T, Hatt H. Dual capacity of a human olfactory receptor. Curr Biol. 2004;14(19):R832–3.
Article
CAS
PubMed
Google Scholar
Cui T, Tsolakis AV, Li SC, Cunningham JL, Lind T, Oberg K, et al. Olfactory receptor 51E1 protein as a potential novel tissue biomarker for small intestine neuroendocrine carcinomas. Eur J Endocrinol. 2013;168(2):253–61.
Article
CAS
PubMed
Google Scholar
Giandomenico V, Cui T, Grimelius L, Oberg KE, Pelosi G, Tsolakis AV. Olfactory receptor 51E1 as a novel target in somatostatin receptor negative lung carcinoids. J Mol Endocrinol. 2013;51(3):277–86.
Article
CAS
PubMed
Google Scholar
Leja J, Essaghir A, Essand M, Wester K, Oberg K, Totterman TH, et al. Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas. Mod Pathol. 2009;22:261–72.
Article
CAS
PubMed
Google Scholar
Weng J, Wang J, Cai Y, Stafford LJ, Mitchell D, Ittmann M, et al. Increased expression of prostate-specific G-protein-coupled receptor in human prostate intraepithelial neoplasia and prostate cancers. Int J Cancer. 2005;113(5):811–8.
Article
CAS
PubMed
Google Scholar
Morita R, Hirohashi Y, Torigoe T, Inoda S, Takahashi A, Mariya T, et al. Olfactory receptor family receptor, family 7, subfamily C, member 1 is a novel marker of colon cancer-initiating cells and is a potent target of immunotherapy. Clin Cancer Res. 2016;22(13):3298–309.
Article
CAS
PubMed
Google Scholar
Muranen TA, Greco D, Fagerholm R, Kilpivaara O, Kampjarvi K, Aittomaki K, et al. Breast tumors from CHEK2 1100delC-mutation carriers: genomic landscape and clinical implications. Breast Cancer Res. 2011;13(5):R90.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wei P, Tang H, Li D. Insights into pancreatic cancer etiology from pathway analysis of genome-wide association study data. PLoS ONE. 2012;7(10):e46887.
Article
CAS
PubMed
PubMed Central
Google Scholar
Sanz G, Leray I, Dewaele A, Sobilo J, Lerondel S, Bouet S, et al. Promotion of cancer cell invasiveness and metastasis emergence caused by olfactory receptor stimulation. PLoS ONE. 2014;9(1):e85110.
Article
PubMed
PubMed Central
Google Scholar
Rodriguez M, Luo W, Weng J, Zeng L, Yi Z, Siwko S, et al. PSGR promotes prostatic intraepithelial neoplasia and prostate cancer xenograft growth through NF-kappaB. Oncogenesis. 2014;3:e114.
Article
CAS
PubMed
PubMed Central
Google Scholar
Cao W, Li F, Yao J, Yu J. Prostate specific G protein coupled receptor is associated with prostate cancer prognosis and affects cancer cell proliferation and invasion. BMC Cancer. 2015;15:915.
Article
PubMed
PubMed Central
Google Scholar
Rodriguez M, Siwko S, Zeng L, Li J, Yi Z, Liu M. Prostate-specific G-protein-coupled receptor collaborates with loss of PTEN to promote prostate cancer progression. Oncogene. 2016;35(9):1153–62.
Article
CAS
PubMed
Google Scholar
Sanz G, Leray I, Grebert D, Antoine S, Acquistapace A, Muscat A, et al. Structurally related odorant ligands of the olfactory receptor OR51E2 differentially promote metastasis emergence and tumor growth. Oncotarget. 2016. https://doi.org/10.18632/oncotarget.13836.
Google Scholar
Kamal FA, Mickelsen DM, Wegman KM, Travers JG, Moalem J, Hammes SR, et al. Simultaneous adrenal and cardiac g-protein-coupled receptor-gbetagamma inhibition halts heart failure progression. J Am Coll Cardiol. 2014;63(23):2549–57.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lehmann DM, Seneviratne AM, Smrcka AV. Small molecule disruption of G protein beta gamma subunit signaling inhibits neutrophil chemotaxis and inflammation. Mol Pharmacol. 2008;73(2):410–8.
Article
CAS
PubMed
Google Scholar
Lin Y, Smrcka AV. Understanding molecular recognition by G protein betagamma subunits on the path to pharmacological targeting. Mol Pharmacol. 2011;80(4):551–7.
Article
CAS
PubMed
PubMed Central
Google Scholar
Smrcka AV, Lehmann DM, Dessal AL. G protein betagamma subunits as targets for small molecule therapeutic development. Comb Chem High Throughput Screen. 2008;11(5):382–95.
Article
CAS
PubMed
PubMed Central
Google Scholar
De Wever O, Hendrix A, De Boeck A, Westbroek W, Braems G, Emami S, et al. Modeling and quantification of cancer cell invasion through collagen type I matrices. Int J Dev Biol. 2010;54(5):887–96.
Article
PubMed
Google Scholar
Rangel-Moreno J, To JY, Owen T, Goldman BI, Smrcka AV, Anolik JH. Inhibition of G protein betagamma subunit signaling abrogates nephritis in lupus-prone mice. Arthritis Rheumatol. 2016;68(9):2244–56.
Article
CAS
PubMed
PubMed Central
Google Scholar
Courboulin A, Sanz G, Breuils-Bonnet S, Quatredeniers M, Vocelle M, Lafond M, et al. Olfactory receptors in pulmonary arterial hypertension: a novel pathway of vascular remodeling? Eur Respir J. 2015. https://doi.org/10.1183/13993003.congress-2015.PA2431.
Google Scholar