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  1. Menopausal status impacts risk for many health outcomes. However, factors including hysterectomy without oophorectomy and Menopausal Hormone Therapy (MHT) can mask menopause, affecting reliability of self-repo...

    Authors: Sarsha Yap, Amy Vassallo, David E. Goldsbury, Usha Salagame, Louiza Velentzis, Emily Banks, Dianne L. O’Connell, Karen Canfell and Julia Steinberg
    Citation: BMC Research Notes 2022 15:88
    Content type: Research note Published on:

  2. A single study conducted about three decades ago on hepatitis D virus (HDV) infection among Baka pygmies in Cameroon reported a very high anti-HDV antibodies prevalence of 46%, but HDV genetic diversity has no...

    Authors: Yacouba Foupouapouognigni, Jacques Delors Toumansie Mfonkou, Onana Boyomo, Antoine Gessain and Richard Njouom
    Citation: BMC Research Notes 2022 15:87
    Content type: Research note Published on:

  3. The COVID-19 pandemic has caused widespread illness and a significant proportion of the infected required hospitalisation for treatment. People in developing countries like India were vulnerable to high hospit...

    Authors: Samir Garg, Kirtti Kumar Bebarta, Narayan Tripathi and C. Krishnendhu
    Citation: BMC Research Notes 2022 15:86
    Content type: Research note Published on:

  4. Cholera is an intestinal infection caused by Vibrio cholerae, it is usually occurs in developing countries that lack of sanitation. In developing country including Indonesia, awareness importance of sanitation is...

    Authors: Andrea Budiman, Kevin Kurnia and Diana E. Waturangi
    Citation: BMC Research Notes 2022 15:63
    Content type: Research note Published on:

  5. We developed an actuator-driven pulsed water jet (ADPJ) device to achieve maximal lesion dissection with minimal risk of normal structural damage. Despite the unique dissection characteristics, there is a risk...

    Authors: Sosuke Kageyama, Atsuhiro Nakagawa, Tomohiro Kawaguchi, Kiyonobu Ohtani, Toshiki Endo, Manabu Kyan, Tetsuya Kusunoki, Yoshiteru Shimoda, Shin-Ichiro Osawa, Masayuki Kanamori, Kuniyasu Niizuma and Teiji Tominaga
    Citation: BMC Research Notes 2022 15:85
    Content type: Research note Published on:

    The Correction to this article has been published in BMC Research Notes 2022 15:279

  6. Streptococcus mutans is one of the principal causative agents of dental caries (tooth decay) found in the oral cavity. Therefore, this study investigates whether selenium nanoparticles (SeNPs) enhance the efficac...

    Authors: Samane Shahmoradi, Aref Shariati, Seyed Mohammad Amini, Nazanin Zargar, Zahra Yadegari and Davood Darban-Sarokhalil
    Citation: BMC Research Notes 2022 15:84
    Content type: Research note Published on:

  7. From previous studies, it is known that the association between fibromyalgia and thyroid autoimmunity diseases exists. On the other hand, it was recently suggested that in many cases thyroid hormone treatment ...

    Authors: Varinen Aleksi, Kosunen Elise and Tuomas H. Koskela
    Citation: BMC Research Notes 2022 15:83
    Content type: Research note Published on:

  8. To establish reference data on required competition age regarding performance levels for both sexes, all swimming strokes, and race distances and to determine the effect of competition age on swimming performa...

    Authors: Dennis-Peter Born, Ina Stäcker, Michael Romann and Thomas Stöggl
    Citation: BMC Research Notes 2022 15:82
    Content type: Research note Published on:

  10. Antibiotics (ABX) are widely used for life-threatening infections and also for routine surgical operations. Compelling evidence suggests that ABX-induced alterations of gut microbiota composition, termed dysbi...

    Authors: Andrew Rodenhouse, M. A. Hassan Talukder, Jung Il Lee, Prem Kumar Govindappa, Mary O’Brien, Kristen M. Manto, Kelsey Lloyd, Grant D. Wandling, Justin R. Wright, Jeremy R. Chen See, Samantha L. Anderson, Regina Lamendella, John P. Hegarty and John C. Elfar
    Citation: BMC Research Notes 2022 15:80
    Content type: Research note Published on:

  11. It has been postulated that social and economic inequalities may shape the distributions of comorbid diabetes and mental illness. This observational cohort study using linked population-based administrative an...

    Authors: Neeru Gupta, Dan Lawson Crouse and Ismael Foroughi
    Citation: BMC Research Notes 2022 15:79
    Content type: Research note Published on:

  14. Glucose-6-phosphate dehydrogenase (G6PD) deficiency offers some protection against malaria; however, the degree of protection is poorly described and likely to vary with G6PD genotype and Plasmodium species. We p...

    Authors: Angela Rumaseb, Jutta Marfurt, Steven Kho, Maria Kahn, Ric N. Price and Benedikt Ley
    Citation: BMC Research Notes 2022 15:76
    Content type: Research note Published on:

  15. The UK House of Commons Science and Technology Committee has called for evidence on the roles that different stakeholders play in reproducibility and research integrity. Of central priority are proposals for i...

    Authors: Flávio Azevedo, Meng Liu, Charlotte R. Pennington, Madeleine Pownall, Thomas Rhys Evans, Sam Parsons, Mahmoud Medhat Elsherif, Leticia Micheli and Samuel J. Westwood
    Citation: BMC Research Notes 2022 15:75
    Content type: Commentary Published on:

  16. A sustainable way of providing essential nutrients from crops for the poor and undernourished is biofortification, through plant breeding. This study characterised the intraspecific variation of selected nutri...

    Authors: Judith S. Nantongo, Juventine B. Odoi, Hillary Agaba and Samson Gwali
    Citation: BMC Research Notes 2022 15:74
    Content type: Research note Published on:

  18. The brown seed coat colour of flax (Linum ustiatissimum) results from proanthocyanidin synthesis and accumulation. Glutathione S-transferases (GSTs), such as the TT19 protein in Arabidopsis, have been implicated ...

    Authors: Lester Young, Leonid Akhov, Manoj Kulkarni, Frank You and Helen Booker
    Citation: BMC Research Notes 2022 15:72
    Content type: Research note Published on:

  19. Acute febrile infections compatible with malaria are the most prevalent presentation at sub-Saharan African health clinics, accounting for 30–50% of outpatient visits. Acute human immunodeficiency virus (HIV) ...

    Authors: Ololade O. Akinnusi, Adebayo J. Bello, Isaac A. Adeleye and Jerry John Nutor
    Citation: BMC Research Notes 2022 15:71
    Content type: Research note Published on:

  20. In this Data note, we provide a raw data set in the form of brief self-guided reflections. We also present the methodological approach to generate these reflections including an educational vignette so that ot...

    Authors: Mario Brondani, Rana Alan and Leeann Donnelly
    Citation: BMC Research Notes 2022 15:70
    Content type: Data note Published on:

  22. The nuclear matrix maintains and regulates chromatin structure. RNA is an integral component of the nuclear matrix and is essential to its structural maintenance. Bombyx mori is a major economic contributor in th...

    Authors: Alekhya Rani Chunduri, Anugata Lima, Resma Rajan and Anitha Mamillapalli
    Citation: BMC Research Notes 2022 15:68
    Content type: Research note Published on:

  23. Transcriptional regulatory modules are usually modelled via a network, in which nodes correspond to genes and edges correspond to regulatory associations between them. In the model yeast Saccharomyces cerevisiae,...

    Authors: Thibault Poinsignon, Mélina Gallopin, Jean-Michel Camadro, Pierre Poulain and Gaëlle Lelandais
    Citation: BMC Research Notes 2022 15:67
    Content type: Research note Published on:

  24. Breast cancer is a critical public health issue and a leading cause of cancer-related deaths among women worldwide. Its early diagnosis and detection can effectively help in increasing the chances of survival ...

    Authors: H. El Agouri, M. Azizi, H. El Attar, M. El Khannoussi, A. Ibrahimi, R. Kabbaj, H. Kadiri, S. BekarSabein, S. EchCharif, C. Mounjid and B. El Khannoussi
    Citation: BMC Research Notes 2022 15:66
    Content type: Research note Published on:

  25. Scientific evidence related to environmental exposures continues to mount. Tools such as evidence mapping support decision making, but can be resource- and time-intensive. We explored “rapid evidence mapping” ...

    Authors: Juleen Lam, Rebecca Elmore, Brian Howard and Ruchir R. Shah
    Citation: BMC Research Notes 2022 15:65
    Content type: Research note Published on:

  27. Most studies in Latin America that evaluate psychological violence at work (PVW) focus on measuring occurrences of PVW. However, the discriminative validity and randomness of instruments used for evaluating in...

    Authors: Luis Fidel Abregú Tueros and Roger dos Santos Rosa
    Citation: BMC Research Notes 2022 15:62
    Content type: Research note Published on:

  30. To describe the clinical profile of minimal invasive procedures performed in gynecology at the national referral hospital in Bhutan. A review of such procedures performed in gynecology was needed to assess the...

    Authors: Sangay Tshering, Thinley Dorji, Namkha Dorji, Renuka Monger, Kesang Choden and Kezang Lhamo
    Citation: BMC Research Notes 2022 15:59
    Content type: Research note Published on:

  31. Many disciplines are facing a “reproducibility crisis”, which has precipitated much discussion about how to improve research integrity, reproducibility, and transparency. A unified effort across all sectors, l...

    Authors: Suzanne L. K. Stewart, Charlotte R. Pennington, Gonçalo R. da Silva, Nick Ballou, Jessica Butler, Zoltan Dienes, Caroline Jay, Stephanie Rossit and Anna Samara
    Citation: BMC Research Notes 2022 15:58
    Content type: Commentary Published on:

  32. RT-qPCR is a reliable method for gene expression analysis, but the accuracy of the quantitative data depends on the appropriate selection of reference genes. A Co-culture system consisting of periodontal ligam...

    Authors: Jiawen Yong, Sabine Groeger, Gisela Ruiz-Heiland and Sabine Ruf
    Citation: BMC Research Notes 2022 15:57
    Content type: Research note Published on:

  33. The current culture system for P. berghei still requires modifications in consistency and long-term maintenance of parasites considering their pathogenicity in culture media. Therefore, this study designed to fur...

    Authors: Haleh Hanifian, Mehdi Nateghpour, Afsaneh Motevalli Haghi, Aref Teimouri, Sepand Razavi and Leila Fariver
    Citation: BMC Research Notes 2022 15:56
    Content type: Research note Published on:

  34. Infertility has a significant impact on the sexual function of couples. The use of herbal medicine has been highly important throughout the history of medicine. The present study was conducted to evaluate the ...

    Authors: Athar Rasekh Jahromi, Zahra Mosallanezhad, Fatemeh Saadat Hosini, Safieh Jamali and Nader Sharifi
    Citation: BMC Research Notes 2022 15:55
    Content type: Research note Published on:

  35. Due to multiple light scattering that occurs inside and between cells, quantitative optical spectroscopy in turbid biological suspensions is still a major challenge. This includes also optical inline determina...

    Authors: Michael Sandmann, Marvin Münzberg, Lena Bressel, Oliver Reich and Roland Hass
    Citation: BMC Research Notes 2022 15:54
    Content type: Research note Published on:

  36. Authors: David Vanegas, Andrea Abril-Novillo, Aleksandr Khachatryan, Lourdes Jerves-Andrade, Eugenia Peñaherrera, Nancy Cuzco, Isabel Wilches, Jessica Calle and Fabián León-Tamariz
    Citation: BMC Research Notes 2022 15:53
    Content type: Correction Published on:

    The original article was published in BMC Research Notes 2021 14:439

  37. Abnormal thyroid function may disrupt sleep architecture. We aimed to determine the frequency of various chronotypes in women with hypothyroidism. We performed a single-center retrospective study at an ambulat...

    Authors: Marilyn A. Arosemena, Alberto R. Ramos, Erin N. Marcus, Katarzyna A. Slota, Joseph Cheung and Pablo R. Castillo
    Citation: BMC Research Notes 2022 15:52
    Content type: Research note Published on:

  38. Various factors contribute to low reproducibility and replicability of scientific findings. Whilst not all of these are necessarily problematic, there is growing acceptance that there is room for improvement. ...

    Authors: Emma Ganley, Anne-Marie Coriat, Sarah Shenow and David Prosser
    Citation: BMC Research Notes 2022 15:51
    Content type: Commentary Published on:

  39. The efficacy of Rhodococcus equi-specific hyperimmune plasma (HIP) is usually evaluated in vitro. Anticoagulants (AC) used for plasma collection can negatively impact bacterial replication but their effect on R. ...

    Authors: Alejandra A. Rivolta, Dana C. Pittman, Amanda J. Kappes, Robert K. Stancil, Clark Kogan and Macarena G. Sanz
    Citation: BMC Research Notes 2022 15:50
    Content type: Research note Published on:

  40. Despite the move to at-home, small-volume collection kits to facilitate large population-based studies of faecal microbial compositional profiling, there remains limited reporting on potential impacts of faeca...

    Authors: Amanda J. Cox, Lily Hughes, Tiffanie M. Nelson, Kyle M. Hatton-Jones, Rebecca Ramsey, Allan W. Cripps and Nicholas P. West
    Citation: BMC Research Notes 2022 15:49
    Content type: Research note Published on:

  41. The aim of this study is to demonstrate an adaptive method that is robust toward environmental fluctuations and provides a real-time measure of plant growth by measuring CO2 consumption. To verify the validity of...

    Authors: Hiroki Gonome, Jun Yamada, Norito Nishimura, Yuta Arai, Minoru Hirai, Naoki Kumagai, Uma Maheswari Rajagopalan and Takahiro Kono
    Citation: BMC Research Notes 2022 15:48
    Content type: Research note Published on:

  42. Campylobacter upsaliensis has been recognized as an emerging pathogen. However, little is known about its survival in the environment. To evaluate its survival capability, we estimated the reduction in viable cou...

    Authors: Walid Elmonir, Torrung Vetchapitak, Tomoko Amano, Takako Taniguchi and Naoaki Misawa
    Citation: BMC Research Notes 2022 15:47
    Content type: Research note Published on:

  43. Acute lymphoblastic leukemia (ALL) is one of the most common cancers in children for which the exact pathogenesis is not yet known. Single-nucleotide variants (SNVs) in different DNA repair genes are reported ...

    Authors: Shahrzad Zehtab, Mahla Sattarzadeh Bardsiri, Roohollah Mirzaee Khalilabadi, Mohsen Ehsan and Ahmad Fatemi
    Citation: BMC Research Notes 2022 15:46
    Content type: Research note Published on:

  45. To disseminate the portable sequencer MinION in developing countries for the main purpose of battling infectious diseases, we found a consortium called Global Research Alliance in Infectious Diseases (GRAID). ...

    Authors: Lucky R. Runtuwene, Nuankanya Sathirapongsasuti, Raweewan Srisawat, Narumon Komalamisra, Josef S. B. Tuda, Arthur E. Mongan, Gabriel O. Aboge, Victoria Shabardina, Wojciech Makalowski, Dela Ria Nesti, Wayan T. Artama, Lan Anh Nguyen-Thi, Kiew-Lian Wan, Byoung-Kuk Na, William Hall, Arnab Pain…
    Citation: BMC Research Notes 2022 15:44
    Content type: Research note Published on:

  46. There are many factors that contribute to the reproducibility and replicability of scientific research. There is a need to understand the research ecosystem, and improvements will require combined efforts acro...

    Authors: Marcus R. Munafò, Chris Chambers, Alexandra Collins, Laura Fortunato and Malcolm Macleod
    Citation: BMC Research Notes 2022 15:43
    Content type: Commentary Published on:

  47. Heart failure (HF) is a chronic disease with growing numbers of patients and a significant compromise in quality of life and high mortality. The main purpose of this study was to evaluate the current practices...

    Authors: Muhammad Siddiqui, Christopher Ripplinger, Hafsah Chalchal and Dakshina Murthy
    Citation: BMC Research Notes 2022 15:41
    Content type: Research note Published on:

  49. The treatment for nonampullary duodenal adenoma remains to have no consensus and established methods. Although endoscopic treatment is minimally invasive, it was reported to cause delayed perforation in more t...

    Authors: Tomotaka Okubo, Ryo Ogawa, Shuhei Ueno, Sunao Ito, Shunsuke Hayakawa, Hiroyuki Sagawa, Tatsuya Tanaka, Hiroki Takahashi, Yoichi Matsuo, Takaya Shimura, Hiromi Kataoka and Shuji Takiguchi
    Citation: BMC Research Notes 2022 15:33
    Content type: Research note Published on:

  50. The aim of this prospective pilot study is to establish an initial database to register patients diagnosed with different types of childhood glaucoma and the set-up of a national registry for childhood glaucom...

    Authors: Fidan A. Aghayeva, Alexander K. Schuster, Heidi Diel, Panagiotis Chronopoulos, Felix M. Wagner, Franz Grehn, Nina Pirlich, Susann Schweiger, Norbert Pfeiffer and Esther M. Hoffmann
    Citation: BMC Research Notes 2022 15:32
    Content type: Research note Published on:
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