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  1. The Australian and New Zealand (ANZ) Massive Transfusion (MT) Registry (MTR) has been established to improve the quality of care of patients with critical bleeding (CB) requiring MT (≥ 5 units red blood cells ...

    Authors: J. C. Oldroyd, K. M. Venardos, N. J. Aoki, A. J. Zatta, Z. K. McQuilten, L. E. Phillips, N. Andrianopoulos, D. J. Cooper, P. A. Cameron, J. P. Isbister and E. M. Wood
    Citation: BMC Research Notes 2016 9:457
    Content type: Research article Published on:

  3. Recent guidelines have recommended vancomycin trough levels of 15–20 mg/L for treatment of serious infections caused by methicillin-resistant Staphylococcus aureus (MRSA). However, high trough levels may increase...

    Authors: Sasima Tongsai and Pornpan Koomanachai
    Citation: BMC Research Notes 2016 9:455
    Content type: Research article Published on:

  4. Systemic chemotherapy with gemcitabine and cisplatin is standard of care for patients with metastatic urothelial bladder cancer. However, resistance formation is common after initial response. The protein Src ...

    Authors: Stefan Vallo, Martin Michaelis, Kilian M. Gust, Peter C. Black, Florian Rothweiler, Hans-Michael Kvasnicka, Roman A. Blaheta, Maximilian P. Brandt, Felix Wezel, Axel Haferkamp and Jindrich Cinatl Jr.
    Citation: BMC Research Notes 2016 9:454
    Content type: Research article Published on:

  5. Major depressive episodes (MDE) are frequent at the population level and are generally associated with severe symptoms that impair performance of activities of daily living of individuals suffering from this c...

    Authors: Iná S. Santos, Beatriz Franck Tavares, Tiago N. Munhoz, Patricia Manzolli, Gisele Bartz de Ávila, Eduardo Jannke and Alicia Matijasevich
    Citation: BMC Research Notes 2016 9:453
    Content type: Research article Published on:

  6. We have previously reported the design, pharmacological properties and imaging application of bradykinin (BK) B2 receptor (B2R) ligands conjugated with fluorophores such as fluorescein derivatives at their N-term...

    Authors: Lajos Gera, Xavier Charest-Morin, Melissa Jean, Hélène Bachelard and François Marceau
    Citation: BMC Research Notes 2016 9:452
    Content type: Research article Published on:

  7. The varicella zoster virus affects the central or peripheral nervous systems upon reactivation, especially when cell-mediated immunity is impaired. Among varicella zoster virus-related neurological syndromes, ...

    Authors: Vincent Luisier, Lalensia Weber, Daniel Fishman, Gérard Praz, Joseph-André Ghika, Didier Genoud and Joelle Nsimire Chabwine
    Citation: BMC Research Notes 2016 9:451
    Content type: Case Report Published on:

  8. Integrated neighborhood approaches (INAs) are increasingly advocated to reinforce formal and informal community networks and support community-dwelling older people. They aim to augment older people’s self-man...

    Authors: Hanna M. van Dijk, Jane M. Cramm, Erwin Birnie and Anna P. Nieboer
    Citation: BMC Research Notes 2016 9:450
    Content type: Research article Published on:

  9. The aim of the study was to evaluate the evolution of patients subject to physical treatment based on guidelines of functional rehabilitation after surgery anterior cruciate ligament reconstruction.

    Authors: Tabata Cristina do Carmo Almeida, Luiz Vinicius de Alcantara Sousa, Diego Monteiro de Melo Lucena, Francisco Winter dos Santos Figueiredo, Vitor Engrácia Valenti, Laércio da Silva Paiva, Luiz Carlos de Abreu and Fernando Adami
    Citation: BMC Research Notes 2016 9:449
    Content type: Research article Published on:

  11. FapR protein from the psychrotrophic species Exiguobacterium antarcticum B7 was expressed and purified, and subsequently evaluated for its capacity to bind to the promoter regions of the fabH1-fabF and fapR-plsX-

    Authors: Rafael A. Baraúna, Diego A. das Graças, Catarina I. P. Nunes, Maria P. C. Schneider, Artur Silva and Marta S. P. Carepo
    Citation: BMC Research Notes 2016 9:447
    Content type: Short Report Published on:

  12. Scleritis is a painful inflammatory process centered in the sclera that may involve the cornea and the underlying uvea. The etiology is commonly idiopathic or autoimmune but some cases are associated with syst...

    Authors: Houssaine Ait Lhaj, Amine Benjelloun, Youssef bouia, Youssef Bennouk, Yassine Mouzari, Youssef El Kamouni and Mohamed Kriet
    Citation: BMC Research Notes 2016 9:446
    Content type: Case Report Published on:

  13. Although a clinician may have the intention of carrying out strategies to reduce cognitive errors, this intention may not be realized especially under heavy workload situations or following a period of interru...

    Authors: Keng Sheng Chew, Jeroen van Merriënboer and Steven J. Durning
    Citation: BMC Research Notes 2016 9:445
    Content type: Research article Published on:

  14. There are increasing reports on nosocomial Mycobacterium massiliense infection, but septic arthritis and osteomyelitis because of that microorganism is rare. This report focuses on the clinical aspects of M. mass...

    Authors: Haekyung Lee, Dohui Hwang, Minchul Jeon, Eunjung Lee, Taehyong Kim, Shi Nae Yu, Yongbeom Kim and Byung-ill Lee
    Citation: BMC Research Notes 2016 9:443
    Content type: Case report Published on:

  15. Developing new clinical practice guidelines (CPGs) can be time-consuming and expensive. A more efficient approach could be to adopt, adapt or contextualise recommendations from existing good quality CPGs so th...

    Authors: Janine Margarita Dizon, Shingai Machingaidze and Karen Grimmer
    Citation: BMC Research Notes 2016 9:442
    Content type: Short Report Published on:

  16. Type 2 diabetes, which is increasing as a public health problem in the low resource settings of Africa has been associated with the high prevalence of micro-vascular complications and increasing levels of macr...

    Authors: Bruck M. Habte, Tedla Kebede, Teferi G. Fenta and Heather Boon
    Citation: BMC Research Notes 2016 9:441
    Content type: Research article Published on:

  17. Obesity is a major risk factor for obstructive sleep apnea, impaired pulmonary function and heart failure, but obesity is also associated with paradoxically low levels of serum N-terminal pro-B-type natriureti...

    Authors: Anne-Marie Gabrielsen, Torbjørn Omland, Mette Brokner, Jan Magnus Fredheim, Jens Jordan, Sverre Lehmann, May Brit Lund, Jøran Hjelmesæth and Dag Hofsø
    Citation: BMC Research Notes 2016 9:440
    Content type: Research article Published on:

  18. Neisseria gonorrhoeae is a bacterium responsible for one of the classic sexually transmitted infection (STI) gonorrhea. Antibiotic resistant strains are emerging at alarming rate. Mult...

    Authors: Seada Ali, Tsegaye Sewunet, Zewdineh Sahlemariam and Gebre Kibru
    Citation: BMC Research Notes 2016 9:439
    Content type: Research article Published on:

  19. Peripheral primitive neuroectodermal tumors are extremely rare tumors in the spine; only 18 cases of extra-dural peripheral primitive neuroectodermal tumor cervical region have been reported. The aim of this repo...

    Authors: Mouna Khmou, Abderrahmane Malihy, Najat Lamalmi, Lamia Rouas and Zaitouna Alhamany
    Citation: BMC Research Notes 2016 9:438
    Content type: Case report Published on:

  20. More people than ever receive care and support from health and social care services. Initiatives to integrate the work of health and social care staff have increased rapidly across the UK but relatively little...

    Authors: Vicky Ward, Lisa Pinkney and Gary Fry
    Citation: BMC Research Notes 2016 9:437
    Content type: Short Report Published on:

  22. There is an unresolved debate on the best screening method for hematuria as a symptom of glomerulonephritis or urological malignancies. The urinary dipstick is generally considered as an imperfect surrogate fo...

    Authors: Aurélien Bataille, Morgane Wetzstein, Alexandre Hertig, Sophie Vimont, Eric Rondeau and Pierre Galichon
    Citation: BMC Research Notes 2016 9:435
    Content type: Short Report Published on:

  25. Newly proliferated oligodendrocyte precursor cells (OPCs) migrate and surround lesions of patients with multiple sclerosis (MS) and other demyelinating diseases, but fail to differentiate into oligodendrocytes...

    Authors: Elen S. Rosler, Karen D. Lariosa-Willingham, Jay S. Tung, Jason C. Dugas, Tassie L. Collins and Dmitri Leonoudakis
    Citation: BMC Research Notes 2016 9:444
    Content type: Technical Note Published on:

  26. Multiple sclerosis is caused by an autoimmune response resulting in demyelination and neural degeneration. The adult central nervous system has the capacity to remyelinate axons in part through the generation ...

    Authors: Karen D. Lariosa-Willingham, Elen S. Rosler, Jay S. Tung, Jason C. Dugas, Tassie L. Collins and Dmitri Leonoudakis
    Citation: BMC Research Notes 2016 9:419
    Content type: Technical Note Published on:

  27. Quality assurance plays an important role in research by assuring data integrity, and thus, valid study results. We aim to describe and share the results of the quality assurance process used to guide the data...

    Authors: Ashley Yamanaka, Marie Kainoa Fialkowski, Lynne Wilkens, Fenfang Li, Reynolette Ettienne, Travis Fleming, Julianne Power, Jonathan Deenik, Patricia Coleman, Rachael Leon Guerrero and Rachel Novotny
    Citation: BMC Research Notes 2016 9:432
    Content type: Research article Published on:

  28. The elderly are considered as special population, as they differ from younger adults in terms of comorbidity, polypharmacy, pharmacokinetics, vulnerability to drug–drug interactions and adverse drug reactions....

    Authors: Fantaye Teka, Gebrehiwot Teklay, Eskindeir Ayalew and Terefe Teshome
    Citation: BMC Research Notes 2016 9:431
    Content type: Research article Published on:

  29. More than 50,000 adult and cord blood samples were collected in Tempus tubes and stored at the Norwegian Institute of Public Health Biobank for future use. In this study, we systematically evaluated and compar...

    Authors: Jeanette Aarem, Gunnar Brunborg, Kaja K. Aas, Kari Harbak, Miia M. Taipale, Per Magnus, Gun Peggy Knudsen and Nur Duale
    Citation: BMC Research Notes 2016 9:430
    Content type: Short Report Published on:

  30. Controlling a myoelectric prosthesis for upper limbs is increasingly challenging for the user as more electrodes and joints become available. Motion classification based on pattern recognition with a multi-ele...

    Authors: Cosima Prahm, Korbinian Eckstein, Max Ortiz-Catalan, Georg Dorffner, Eugenijus Kaniusas and Oskar C. Aszmann
    Citation: BMC Research Notes 2016 9:429
    Content type: Technical Note Published on:

  31. In recent years, measurement of cerebral regional oxygen saturation (rSO2) has attracted attention during resuscitation. However, serial changes of cerebral rSO2 in pre-hospital settings are unclear. The objectiv...

    Authors: Tomoya Hirose, Tadahiko Shiozaki, Junji Nomura, Yasuto Hamada, Keiichi Sato, Kazuya Katsura, Naoki Ehara, Akinori Wakai, Kentaro Shimizu, Mitsuo Ohnishi, Sumito Hayashida, Daikai Sadamitsu and Takeshi Shimazu
    Citation: BMC Research Notes 2016 9:428
    Content type: Research article Published on:

  32. In pea seeds (Pisum sativum L.), the presence of the Def locus determines abscission event between its funicle and the seed coat. Cell wall remodeling is a necessary condition for abscission of pea seed. The chan...

    Authors: YeonKyeong Lee, Kwadwo Owusu Ayeh, Mike Ambrose and Anne Kathrine Hvoslef-Eide
    Citation: BMC Research Notes 2016 9:427
    Content type: Research article Published on:

  33. Lymphangiomas are a heterogeneous group of congenital vascular malformations characterized by cystic dilation of lymphatic vessels. They can occur at any age, but they are more common during childhood and in c...

    Authors: Sebastian Gómez-Galán, Manuel Santiago Mosquera-Paz, Jorge Ceballos, Paola Andrea Cifuentes-Grillo and Laura Gutiérrez-Soriano
    Citation: BMC Research Notes 2016 9:426
    Content type: Case Report Published on:

  34. The Danish Neuro-Oncology Registry (DNOR) is a nationwide clinical cancer database that has prospectively registered data on patients with gliomas since January 2009. The purpose of this study was to describe ...

    Authors: Steinbjørn Hansen, Jan Nielsen, René J. Laursen, Birthe Krogh Rasmussen, Bente Mertz Nørgård, Kim Oren Gradel and Rikke Guldberg
    Citation: BMC Research Notes 2016 9:425
    Content type: Research article Published on:

  35. Community-based health insurance (CBHI) schemes are an emerging tool for providing financial protection against health-related poverty. In Ethiopia, CBHI is being piloted in 13 districts, but community experie...

    Authors: Abebe Sorsa Badacho, Kora Tushune, Yohannes Ejigu and Tezera Moshago Berheto
    Citation: BMC Research Notes 2016 9:424
    Content type: Research article Published on:

  36. Influenza is an acute respiratory illness and has become a serious public health problem worldwide. The need to study the HA and NA genes in influenza A virus is essential since these genes frequently undergo ...

    Authors: Agustiningsih Agustiningsih, Hidayat Trimarsanto, Vivi Setiawaty, I. Made Artika and David Handojo Muljono
    Citation: BMC Research Notes 2016 9:423
    Content type: Research article Published on:

  37. Shigella, gram negative bacterium, is responsible for Shigellosis/bacillary dysentery. It is a global concern although it predominates in developing countries. These are Shigella dysen...

    Authors: Atsebaha Gebrekidan Kahsay and Saravanan Muthupandian
    Citation: BMC Research Notes 2016 9:422
    Content type: Research article Published on:

  39. From 2012–2015, the Departments of Obstetrics and Gynecology and of Pediatrics at the University of Copenhagen conducted a project, “Internationalization at Home ”, offering clinical teaching in English. The p...

    Authors: L. Nilas, E. C. Løkkegaard, J. B. Laursen, J. Kling and D. Cortes
    Citation: BMC Research Notes 2016 9:420
    Content type: Research article Published on:

  40. Single nucleotide polymorphism (SNP) discovery is an important goal of many studies. However, the number of ‘putative’ SNPs discovered from a sequence resource may not provide a reliable indication of the numb...

    Authors: Emily Humble, Michael A. S. Thorne, Jaume Forcada and Joseph I. Hoffman
    Citation: BMC Research Notes 2016 9:418
    Content type: Technical Note Published on:

  41. Crohn disease has low prevalence in Sri Lanka while compared to the West, while intestinal tuberculosis is common in the region. Since clinical, endoscopic and investigation features of Crohn disease overlap w...

    Authors: Madunil A. Niriella, S. Kuleesha Kodisinghe, Arjuna P. De Silva, Janaki Hewavisenthi and Hithanadura J. de Silva
    Citation: BMC Research Notes 2016 9:417
    Content type: Case Report Published on:

  42. In contrast to percutaneous atrial septal occluder device, surgical patch closure of atrial defects was known to be no infective endocarditis risk.

    Authors: Estelle Honnorat, Piseth Seng, Alberto Riberi, Gilbert Habib and Andreas Stein
    Citation: BMC Research Notes 2016 9:416
    Content type: Case report Published on:

  43. Young people are generally reluctant to seek professional help when experiencing problems. However, past experience of services is often cited as increasing the intention to seek help, therefore those with a h...

    Authors: Ruth Spence, Matthew Owens-Solari and Ian Goodyer
    Citation: BMC Research Notes 2016 9:415
    Content type: Research article Published on:

  44. Infection of cardiac implantable electronic devices is a serious cardiovascular disease and it is associated with a high mortality. Mycobacterium species may rarely cause cardiac implantable electronic devices in...

    Authors: Bandar Al-Ghamdi, Hassan El Widaa, Maie Al Shahid, Mohammed Aladmawi, Jawaher Alotaibi, Aly Al Sanei and Magid Halim
    Citation: BMC Research Notes 2016 9:414
    Content type: Case Report Published on:

  45. Chorea is a rare complication of uncontrolled type II diabetes. We report for the first time in Tanzania a case of type II diabetes presenting with a hyperglycaemia-induced hemichorea.

    Authors: Flora Ruhangisa, Henry Stephen, Jacob Senkondo, Amos Mwasamwaja, Said Kanenda, Saleh Mbarak, Nyasatu Chamba, Kajiru Kilonzo, William Howlett, Isaack Lyaruu and Elichilia Shao
    Citation: BMC Research Notes 2016 9:413
    Content type: Case report Published on:

  46. Plate developer is a chemical used in the printing industry and is a corrosive alkaline agent containing sodium metasilicate as the main substance. Plate developer poisoning is rare. Literature search revealed...

    Authors: B. G. A. Rathnamali, G. Samarajiwa, D. D. K. Abeyratne, G. N. D. Perera and S. B. Gunatilake
    Citation: BMC Research Notes 2016 9:412
    Content type: Case report Published on:

  47. Activity monitoring is important to establish accurate daily physical activity levels in children with cerebral palsy (CP). However, few studies address issues around inclusion or exclusion of step count data;...

    Authors: Nichola C. Wilson, Suzie Mudge and N. Susan Stott
    Citation: BMC Research Notes 2016 9:411
    Content type: Research article Published on:

  48. Hepatitis B virus (HBV) infection in the health setting is a global public health problem. The risk of occupational exposure to HBV among health care workers is a major concern, especially among students in he...

    Authors: Abdnur Abdela, Berhanu Woldu, Kassahun Haile, Biniam Mathewos and Tekalign Deressa
    Citation: BMC Research Notes 2016 9:410
    Content type: Research article Published on:

  49. Tuberculosis is endemic in India and almost 40 % of the Indian population is infected with tubercle bacilli. Tuberculosis being a great mimicker of infectious as well as non infectious diseases and recent rise...

    Authors: Pratyush Kumar, Kunal Chawla, Pooja Khosla and Sunil Jain
    Citation: BMC Research Notes 2016 9:409
    Content type: Case Report Published on:

  50. The awakening and breathing coordination, delirium, and early mobility (ABCDE) bundle is a multicomponent complex intervention that improves outcomes for critically ill adults yet is inconsistently implemented...

    Authors: Deena Kelly Costa, Jennifer Dammeyer, Matthew White, Jose Galinato, Robert Hyzy, Milisa Manojlovich and Anne Sales
    Citation: BMC Research Notes 2016 9:408
    Content type: Short Report Published on:
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