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  1. Structural biomolecular data are commonly stored in the PDB format. The PDB format is widely supported by software vendors because of its simplicity and readability. However, the PDB format cannot fully addres...

    Authors: Petr Čech and Daniel Svozil

    Citation: BMC Research Notes 2011 4:121

    Content type: Technical Note

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  2. Sex-specific DNA markers can serve as tools for molecular sex identification, as well as for population genetic inferences. We investigated the potential utility of a microsatellite marker located on sex chrom...

    Authors: Takahito Shikano, Gábor Herczeg and Juha Merilä

    Citation: BMC Research Notes 2011 4:119

    Content type: Short Report

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  3. The transcription factor Hypoxia-Inducible Factor-1α is a master regulator of the cellular response to low oxygen concentration. Compound C, an inhibitor of AMP-activated kinase, has been reported to inhibit h...

    Authors: Yee Liu Chua and Thilo Hagen

    Citation: BMC Research Notes 2011 4:117

    Content type: Correspondence

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  4. Heat shock proteins are acute phase proteins that are upregulated in inflammation or following thermal stress. We analyzed the presence of the heat shock protein 70 (Hsp 70) in choroidal neovascular (CNV) memb...

    Authors: Andreas PW Jöres, Dörthe Carstesen, Gabriele Thumann, Peter Walter and Andreas WA Weinberger

    Citation: BMC Research Notes 2011 4:115

    Content type: Research article

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  5. Staphylococcus lugdunensis is an important human pathogen that causes potentially fatal endocarditis, osteomyelitis and skin and soft tissue infections similar to diseases caused by Staphylococcus aureus. Neverth...

    Authors: Florian Szabados, Yasmina Nowotny, Lennart Marlinghaus, Miriam Korte, Sandra Neumann, Martin Kaase and Sören G Gatermann

    Citation: BMC Research Notes 2011 4:113

    Content type: Short Report

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  6. In some countries every citizen has the right to obtain a designated general practitioner. However, each individual may have preferences that cannot be fulfilled due to shortages of some kind. The questions ra...

    Authors: Jostein Lillestøl, Jan Ubøe, Yngve Rønsen and Per Hjortdahl

    Citation: BMC Research Notes 2011 4:112

    Content type: Short Report

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  7. An innovative approach to learning public health by using feature-length commercial movies was piloted in the fourth year of a medical degree. We aimed to explore how students responded to this approach and th...

    Authors: Peter Gallagher, Nick Wilson, Richard Edwards, Rachael Cowie and Michael G Baker

    Citation: BMC Research Notes 2011 4:111

    Content type: Short Report

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  8. Escherichia coli O157:H7 is the most common serovar of enterohemorrhagic E. coli associated with serious human disease outbreaks. Cattle are the main reservoir with E. coli O157:H7 inducing hemorrhagic enteritis ...

    Authors: Danica Baines, Stephanie Erb, Ross Lowe, Kelly Turkington, Emil Sabau, Gretchen Kuldau, Jean Juba, Luke Masson, Alberto Mazza and Ray Roberts

    Citation: BMC Research Notes 2011 4:110

    Content type: Short Report

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  9. Vibrio cholerae O1 and V. cholerae O139 infect humans, causing the diarrheal and waterborne disease cholera, which is a worldwide health problem. V. cholerae and the free-living amoebae Acanthamoeba species are p...

    Authors: Salah Shanan, Hadi Abd, Ingela Hedenström, Amir Saeed and Gunnar Sandström

    Citation: BMC Research Notes 2011 4:109

    Content type: Short Report

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  10. Poor quality of sleep among alcoholics and persons undergoing alcohol withdrawal has been described as a possible cause of alcohol relapse. It has been suggested earlier that nitrous oxide gas has a significan...

    Authors: Tuuli Lahti, Taina Methuen, Risto Roine, Kaija-Liisa Seppä, David Sinclair, Markku Partinen and Hannu Alho

    Citation: BMC Research Notes 2011 4:108

    Content type: Research article

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  11. Oxygen supplementation is commonly given to the patients with severe pneumonia including Legionella disease. Recent data suggested that apoptosis may play an important role, not only in the pathogenesis of Legion...

    Authors: Tsuneharu Maeda, Soichiro Kimura, Tetsuya Matsumoto, Yoshinari Tanabe, Fumitake Gejyo and Keizo Yamaguchi

    Citation: BMC Research Notes 2011 4:107

    Content type: Short Report

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  12. Guidelines recommend an early initiation of aspirin treatment in patients with acute cerebral ischemia. Comparative studies on the best starting dose for initiating aspirin therapy to achieve a rapid antiplate...

    Authors: Saskia H Meves, Horst Neubauer, Ursula Overbeck and Heinz G Endres

    Citation: BMC Research Notes 2011 4:106

    Content type: Research article

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  13. Type D personality has been associated in the past with increased cardiovascular mortality among patients with established coronary heart disease. Very few studies have investigated the association of type D p...

    Authors: Dimitrios Tziallas, Michael S Kostapanos, Petros Skapinakis, Haralampos J Milionis, Thanos Athanasiou, Moses S Elisaf and Venetsanos Mavreas

    Citation: BMC Research Notes 2011 4:105

    Content type: Short Report

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  14. One important physiological response to environmental stress in animals is change in gene expression. To obtain reliable data from gene expression studies using RT-qPCR it is important to evaluate a set of pos...

    Authors: Ingrid A Aursnes, Anne L Rishovd, Hans E Karlsen and Tor Gjøen

    Citation: BMC Research Notes 2011 4:104

    Content type: Short Report

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  15. Hemoglobin A2' (delta 16 Gly → Arg) is globally the commonest delta chain variant of HbA2. It is clinically and hematologically silent but its sole importance lies in the underestimation of HbA2 quantity durin...

    Authors: Maliha Nusrat, Bushra Moiz, Amna Nasir and Mashhooda Rasool Hashmi

    Citation: BMC Research Notes 2011 4:103

    Content type: Short Report

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  16. Based on our clinical experience, the H-reflex amplitude asymmetry might be an earlier sign of nerve root involvement than latency in patients with S1 radiculopathy. However, no data to support this assumption...

    Authors: Hesham N Alrowayeh and Mohamed A Sabbahi

    Citation: BMC Research Notes 2011 4:102

    Content type: Research article

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  17. Depression and anxiety disorders have a high disease burden and as many as 15% of young people report mental health problems. Binge drinking, which is a particularly harmful way of consuming alcohol, is common...

    Authors: Marie-José Theunissen, Maria Jansen and Anke van Gestel

    Citation: BMC Research Notes 2011 4:100

    Content type: Short Report

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  18. Colletotrichum is one of the most widespread and important genus of plant pathogenic fungi worldwide. Various species of Colletotrichum are the causative agents of anthracnose disease in plants, which is a severe...

    Authors: Bungonsiri Intra, Isada Mungsuntisuk, Takuya Nihira, Yasuhiro Igarashi and Watanalai Panbangred

    Citation: BMC Research Notes 2011 4:98

    Content type: Research article

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  19. Machine learning techniques have been widely applied to biological sequences, e.g. to predict drug resistance in HIV-1 from sequences of drug target proteins and protein functional classes. As deletions and in...

    Authors: Dominik Heider, Jens Verheyen and Daniel Hoffmann

    Citation: BMC Research Notes 2011 4:94

    Content type: Short Report

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  20. The PneuX System is a novel endotracheal tube and tracheal seal monitor, which has been designed to minimise the aspiration of oropharyngeal secretions. We aimed to determine the incidence of ventilator-associ...

    Authors: Alex Doyle, Andrew Fletcher, Joseph Carter, Mark Blunt and Peter Young

    Citation: BMC Research Notes 2011 4:92

    Content type: Short Report

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  21. Rural Australians face a higher mental health and lifestyle disease burden (obesity, diabetes and cardiovascular disease) than their urban counterparts. Our ongoing research reveals that the Australian farming...

    Authors: Susan Brumby, Ananda Chandrasekara, Scott McCoombe, Peter Kremer and Paul Lewandowski

    Citation: BMC Research Notes 2011 4:89

    Content type: Hypothesis

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  22. Atlantic salmon (Salmo salar L.) is an environmentally and economically important organism and its gene content is reasonably well characterized. From a transcriptional standpoint, it is important to characterize...

    Authors: Stuart G Jantzen, Dan S Sanderson, Kris R von Schalburg, Motoshige Yasuike, Francesco Marass and Ben F Koop

    Citation: BMC Research Notes 2011 4:88

    Content type: Data Note

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  23. Amongst the extensive literature on immunohistochemical profile of breast cancer, very little is found on populations exposed to a potential risk factor such as depleted uranium. This study looked at the immun...

    Authors: Mais M Al-Mumen, Asad A Al-Janabi, Alaa S Jumaa, Kaswer M Al-Toriahi and Akeel A Yasseen

    Citation: BMC Research Notes 2011 4:87

    Content type: Project Note

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  24. Proteomic techniques allow researchers to perform detailed analyses of cellular states and many studies are published each year, which highlight large numbers of proteins quantified in different samples. Howev...

    Authors: Jenna Kenyani, J Alberto Medina-Aunon, Salvador Martinez-Bartolomé, Juan-Pablo Albar, Jonathan M Wastling and Andrew R Jones

    Citation: BMC Research Notes 2011 4:86

    Content type: Data Note

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  25. Secondary metabolites are reported to interfere with the isolation of RNA particularly with the recipes that use guanidinium-based salt. Such interference was observed in isolation of RNA with medicinal plants...

    Authors: Sanjay Ghawana, Asosii Paul, Hitesh Kumar, Arun Kumar, Harsharan Singh, Pardeep K Bhardwaj, Arti Rani, Ravi S Singh, Jyoti Raizada, Kashmir Singh and Sanjay Kumar

    Citation: BMC Research Notes 2011 4:85

    Content type: Technical Note

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  26. The accurate determination of the number of copies of a gene in the genome (gene dosage) is essential for a number of genetic analyses. Quantitative real time PCR (qPCR) with TaqMan detection has shown advanta...

    Authors: Yolanda Bel, Juan Ferré and Baltasar Escriche

    Citation: BMC Research Notes 2011 4:84

    Content type: Short Report

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  27. A high quality of timely delivered medical appraisals is crucial for social and other insurances to judge possible occupational reintegration measures for patients with medical conditions who are in danger to ...

    Authors: Klaus Eichler, Daniel Imhof, Yvonne Bollag, Susanna Stöhr, Niklaus Gyr and Holger Auerbach

    Citation: BMC Research Notes 2011 4:83

    Content type: Short Report

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  28. Unisexual vertebrates have been demonstrated to reproduce by gynogenesis, hybridogenesis, parthenogenesis, or kleptogenesis, however, it is uncertain how the reproduction mode contributes to the clonal diversi...

    Authors: Zhong-Wei Wang, Hua-Ping Zhu, Da Wang, Fang-Fang Jiang, Wei Guo, Li Zhou and Jian-Fang Gui

    Citation: BMC Research Notes 2011 4:82

    Content type: Research article

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  29. The West Sumatra earthquake that occurred on September 30, 2009, caused severe damage in some districts, including Padang Pariaman. As Padang Pariaman is an earthquake-prone area, disaster and emergency manage...

    Authors: Ahmad Fuady, Trevino A Pakasi and Muchtaruddin Mansyur

    Citation: BMC Research Notes 2011 4:81

    Content type: Short Report

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  30. Pyogenic hepatic abscesses are relatively rare, though untreated are uniformly fatal. A recent paradigm shift in the management of liver abscesses, facilitated by advances in diagnostic and interventional radi...

    Authors: Helen M Heneghan, Nuala A Healy, Sean T Martin, Ronan S Ryan, Niamh Nolan, Oscar Traynor and Ronan Waldron

    Citation: BMC Research Notes 2011 4:80

    Content type: Research article

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  31. The present study represents a genome-wide transcriptomic analysis of the response of the model streptomycete Streptomyces coelicolor A3(2) M145 to fermentor culture in Modified Evans Media limited, respectively,...

    Authors: Richard A Lewis, Sanjay K Shahi, Emma Laing, Giselda Bucca, Georgios Efthimiou, Michael Bushell and Colin P Smith

    Citation: BMC Research Notes 2011 4:78

    Content type: Short Report

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  32. Clostridium difficile is the major cause of pseudomembranous colitis associated with antibiotic use, and the spread of the hypervirulent epidemic ribotype 027/NAP-1 strain across hospitals worldwide has re-focuse...

    Authors: Li-Yang Hsu, Thean Yen Tan, Tse Hsien Koh, Andrea L Kwa, Prabha Krishnan, Nancy W Tee and Roland Jureen

    Citation: BMC Research Notes 2011 4:77

    Content type: Short Report

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  33. Research undertaken in developing countries has assessed discrepancies in police reporting of Road Traffic Injury (RTI) for urban settings only. The objective of this study was to assess differences in RTI rep...

    Authors: Junaid A Bhatti, Junaid A Razzak, Emmanuel Lagarde and Louis-Rachid Salmi

    Citation: BMC Research Notes 2011 4:75

    Content type: Research article

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  34. Candida species including Candida krusei have become common pathogens, especially in immune-compromised patients. Pellicle on the surface of incubating nutrient broth extending with an adherent film above the bro...

    Authors: Jacob Fleischmann and Elia M Sripuntanagoon

    Citation: BMC Research Notes 2011 4:74

    Content type: Short Report

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  35. Two general approaches to prokaryotic live-cell imaging have been employed to date, growing bacteria on thin agar pads or growing bacteria in micro-channels. The methods using agar pads 'sandwich' the cells be...

    Authors: Graham Joyce, Brian D Robertson and Kerstin J Williams

    Citation: BMC Research Notes 2011 4:73

    Content type: Technical Note

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  36. Both low birth weight, an indicator of intrauterine growth restriction, and low grade systemic inflammation depicted by high sensitivity C-reactive protein (hs-CRP) have emerged as independent predictors of ca...

    Authors: Azad R Bhuiyan, Sathanur R Srinivasan, Wei Chen, Mario J Azevedo and Gerald S Berenson

    Citation: BMC Research Notes 2011 4:71

    Content type: Short Report

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