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  1. Doppler echocardiographic aortic valve peak velocity and peak pressure gradient assessment across the aortic valve (AV) is the mainstay for diagnosing aortic stenosis. Four-dimensional flow cardiovascular magn...

    Authors: Ciaran Grafton-Clarke, Paul Njoku, Jean-Paul Aben, Leon Ledoux, Liang Zhong, Jos Westenberg, Andrew Swift, Gareth Archer, James Wild, Rod Hose, Marcus Flather, Vassilios S. Vassiliou and Pankaj Garg
    Citation: BMC Research Notes 2022 15:151
  2. Green synthesized iron(III) oxide (Fe3O4) nanoparticles are gaining appeal in targeted drug delivery systems because of their low cost, fast processing and nontoxicity. However, there is no known research work un...

    Authors: Henry Fenekansi Kiwumulo, Haruna Muwonge, Charles Ibingira, Michael Lubwama, John Baptist Kirabira and Robert Tamale Ssekitoleko
    Citation: BMC Research Notes 2022 15:149
  3. The nucleoside diphosphate linked moiety X (Nudix)-Type motif 15 (NUDT15) enzyme is involved in thiopurine metabolism. Genetic variants in the NUDT15 gene result in decreased NUDT15 activity, which in addition to...

    Authors: Kok-Siong Poon, Izz Irfan B. Imran, Silvester Kheng-Han Chew, Patrice Tan and Karen Mei-Ling Tan
    Citation: BMC Research Notes 2022 15:148
  4. Main malaria diagnosis is based on microscopic examination combined with rapid diagnostic tests. Both methods have low sensitivity and specificity. Loop-mediated isothermal amplification techniques have shown ...

    Authors: Alexandra Martín-Ramírez, Marta Lanza, Shamilah Hisam, Ana Perez-Ayala and José M. Rubio
    Citation: BMC Research Notes 2022 15:147
  5. Mitral Valve Prolapse (MVP) is a common valvular abnormality accounting for 2% of the population. There is a reported association between pes planus (PP) and MVP in some syndromes such as Marfan. However, this...

    Authors: Antoine AbdelMassih, Rafeef Hozaien, Fady Mishriky, Mark Michael, Mostafa AmanAllah, Nada Ali, Nadine ElGamal, Omar Medhat, Mona Kamel, Rasha Helmy, Mai Sarhan, Hams Attalla, Omneya Dawoud, Athar Marwan and Mohamed Ghobashy
    Citation: BMC Research Notes 2022 15:145
  6. SARS-CoV-2 is the cause of COVID-19, the rapidly spreading pandemic. When SARS-CoV-2 enters the target cells in the respiratory system, the spike glycoprotein binds to a cellular receptor angiotensin convertin...

    Authors: Makoto Nogami, Tomoaki Hoshi, Yoko Toukairin, Tomomi Arai and Tadashi Nishio
    Citation: BMC Research Notes 2022 15:144
  7. People experiencing homelessness often encounter progressive illness(es) earlier and are at increased risk of mortality compared to the housed population. There are limited resources available to serve this po...

    Authors: Cait Vihvelin, Viraji Rupasinghe, Jean Hughes, Jeff Karabanow and Lori E. Weeks
    Citation: BMC Research Notes 2022 15:142
  8. The last decade has seen renewed concern within the scientific community over the reproducibility and transparency of research findings. This paper outlines some of the various responsibilities of stakeholders...

    Authors: Thomas Rhys Evans, Madeleine Pownall, Elizabeth Collins, Emma L. Henderson, Jade S. Pickering, Aoife O’Mahony, Mirela Zaneva, Matt Jaquiery and Tsvetomira Dumbalska
    Citation: BMC Research Notes 2022 15:141
  9. This study was to explore the most appropriate radiomics modeling method to predict the progression-free survival of EGFR-TKI treatment in advanced non-small cell lung cancer with EGFR mutations. Different mac...

    Authors: Jian-man Zhu, Lei Sun, Linjing Wang, Tong-Chong Zhou, Yawei Yuan, Xin Zhen and Zhi-Wei Liao
    Citation: BMC Research Notes 2022 15:140
  10. Hypertrophic cardiomyopathy (HCM) is a common genetic disease with diverse morphology, symptoms, and prognosis. Hypertrophied myocardium metabolism has not been explored in detail. We assessed the association ...

    Authors: Keitaro Akita, Kenji Kikushima, Takenori Ikoma, Ariful Islam, Tomohito Sato, Taisei Yamamoto, Tomoaki Kahyo, Mitsutoshi Setou and Yuichiro Maekawa
    Citation: BMC Research Notes 2022 15:139
  11. Himetobi P virus (HiPV) is an insect virus belonging to the genus Cripavirus in the Dicistroviridae family within the Picornavirales order. Himetobi P strain. Sh.Moghaddam is the first study reported, was isolate...

    Authors: Mohammad Reza Rezapanah, Zahra Ziafati Kafi, Iradj Ashrafi Tamai, Naser Sadri, Ali Hojabr Rajeoni, Fahimeh Jamiri and Arash GhalyanchiLangeroudi
    Citation: BMC Research Notes 2022 15:138
  12. Canine dirofilariasis is a mosquito borne zoonotic filarial parasitic disease caused by Dirofilaria species. In Sri Lanka, human dirofilariasis is endemic and well documented. Even though canine dirofilariasis is...

    Authors: Randima Dasanayake, Thivya Balendran, Dhilma Atapattu and Devika Iddawela
    Citation: BMC Research Notes 2022 15:137
  13. These data were collected to generate a novel reference metagenome for the sponge Halichondria panicea and its microbiome for subsequent differential expression analyses.

    Authors: Brian W. Strehlow, Astrid Schuster, Warren R. Francis and Donald E. Canfield
    Citation: BMC Research Notes 2022 15:135
  14. Since 2017, an increasing number of opioid overdoses in Oslo, Norway, has been categorized as involving unspecified opioids, as noted in the patient records by the doctor treating the patient. In this study we...

    Authors: Zahra Zeineb Iqbal, Thanh Mai Thi Nguyen, Mette Brekke and Odd Martin Vallersnes
    Citation: BMC Research Notes 2022 15:134
  15. Elizabethkingia meningoseptica is a multidrug resistance strain which primarily causes meningitis in neonates and immunocompromised patients. Being a nosocomial infection causing agent, less information is availa...

    Authors: Neha Girdhar, Nilima Kumari and A. Krishnamachari
    Citation: BMC Research Notes 2022 15:133
  16. This paper reports HIV prevalence, incidence, progress towards the UNAIDS (90-90-90) targets, and HIV drug resistance among adolescents living with HIV in South Africa. We conducted secondary analyses using da...

    Authors: Naidoo Inbarani, Takatshana Sinovuyo, Sewpaul Ronel, Jooste Sean, Siyanai Zhou, Maseko Goitseone, Moyo Sizulu, Zuma Khangelani, Mabaso Musawenkosi and Nompumelelo Zungu
    Citation: BMC Research Notes 2022 15:132
  17. The present study investigates if symptoms of COVID-19 contagion in different social contexts (cohabitants, family, acquaintances, and others) are associated with university students' own self-reported symptom...

    Authors: Claes Andersson, Marcus Bendtsen, Olof Molander, Lilian Granlund, Naira Topooco, Karin Engström, Petra Lindfors and Anne H. Berman
    Citation: BMC Research Notes 2022 15:131
  18. The actual impact of the pandemic on COVID-19 specific mortality is still unclear due to the variability in access to diagnostic tools. This study aimed to estimate the excess all-cause mortality in Iran until...

    Authors: Seyed Amir Ahmad Safavi-Naini, Yeganeh Farsi, Walid Q. Alali, Ali Solhpour and Mohamad Amin Pourhoseingholi
    Citation: BMC Research Notes 2022 15:130
  19. Insulin-like growth factor (IGF)-1 participates in modulating immunity and inflammation. Its bioactivity is controlled by six IGF-binding proteins (IGFBP-1 to IGFBP-6). In particular, the IGFBP-3 level is repo...

    Authors: Hanna Lee, Young Sun Suh, Sang-Il Lee, Yun-Hong Cheon, Mingyo Kim, Hae Sook Noh and Hyun-Ok Kim
    Citation: BMC Research Notes 2022 15:128
  20. Journal peer review regulates the flow of ideas through an academic discipline and thus has the power to shape what a research community knows, actively investigates, and recommends to policymakers and the wid...

    Authors: Alexandru Marcoci, Ans Vercammen, Martin Bush, Daniel G. Hamilton, Anca Hanea, Victoria Hemming, Bonnie C. Wintle, Mark Burgman and Fiona Fidler
    Citation: BMC Research Notes 2022 15:127
  21. ‘Candidatus Liberibacter asiaticus’ (CLas) is associated with the devastating citrus ‘greening’ disease. All attempts to achieve axenic growth and complete Koch’s postulates with CLas have failed to date, at best...

    Authors: Lulu Cai, Mukesh Jain, Alejandra Munoz-Bodnar, Jose C. Huguet-Tapia and Dean W. Gabriel
    Citation: BMC Research Notes 2022 15:125
  22. To design and construct a new synthetic nanobody library using a structure-based approach that seeks to maintain high protein stability and increase the number of functional variants within the combinatorial s...

    Authors: Ernesto Moreno, Mario S. Valdés-Tresanco, Andrea Molina-Zapata and Oliberto Sánchez-Ramos
    Citation: BMC Research Notes 2022 15:124
  23. The aim of this study is to determine the metabolic impact of a nutrition education program on metabolic parameters and the presence of metabolic syndrome (MetS).

    Authors: Quintí Foguet-Boreu, Mireia Vilamala-Orra, Cristina Vaqué-Crusellas, Pere Roura-Poch, Montse Assens Tauste, Judit Bori Vila, Jose Manuel Santos-López and Ruben del Río Sáez
    Citation: BMC Research Notes 2022 15:122
  24. How do birds navigate their way? It is one of the interesting question about homing pigeons, however the genetic of navigation has reminded as a puzzle. Optic lobe, olfactory bulb, hippocampus and cere were co...

    Authors: Hamed Kharrati-Koopaee, Ali Esmailizadeh and Fatemeh Sabahi
    Citation: BMC Research Notes 2022 15:121
  25. Due to the increase of type 2 diabetes (T2D), the number of patients in treatment with multiple anti-diabetic agents is increased. According to the recent recommendation of treatment guidelines, sodium-glucose...

    Authors: Makoto Fujiwara, Masaru Shimizu, Yuko Maejima and Kenju Shimomura
    Citation: BMC Research Notes 2022 15:120
  26. A clinical trial carried out in patients hospitalized for clinical and surgical conditions. This study evaluated the effectiveness of text messaging interventions (TM) versus telephone counseling (TC) to promo...

    Authors: Lígia Menezes do Amaral, Telmo Mota Ronzani, Erica Cruvinel, Kimber Richter, Rafaela de Oliveira Andrade, Isabella Oliveira Lanzieri, Ângela Caroline Dias Albino Destro de Macêdo and Isabel Cristina Gonçalves Leite
    Citation: BMC Research Notes 2022 15:119
  27. It remains unclear that the relationship between sprint and/or endurance performance and salivary immunological factors and stress hormones in athletes. The aim of this study was to investigate if salivary imm...

    Authors: Masataka Uchida, Tadashi Suga, Masafumi Terada and Tadao Isaka
    Citation: BMC Research Notes 2022 15:118
  28. This study was aimed to assess the enzymatic activity and pathogenicity potential of Beauveria bassiana and Metarhizium anisopliae against whiteflies in Ethiopia.

    Authors: Amha Gebremariam, Yonas Chekol and Fassil Assefa
    Citation: BMC Research Notes 2022 15:117
  29. Increasingly, policies are being introduced to reward and recognise open research practices, while the adoption of such practices into research routines is being facilitated by many grassroots initiatives. How...

    Authors: Olivia S. Kowalczyk, Alexandra Lautarescu, Elisabet Blok, Lorenza Dall’Aglio and Samuel J. Westwood
    Citation: BMC Research Notes 2022 15:116
  30. The redbanded stink bug (RBSB), Piezodorus guildinii (Hemiptera: Pentatomidae), is native to the Caribbean Basin and is currently considered an invasive pest in Florida, Louisiana, Mississippi, and Texas in the s...

    Authors: Surya Saha, K. Clint Allen, Lukas A. Mueller, Gadi V. P. Reddy and Omaththage P. Perera
    Citation: BMC Research Notes 2022 15:115
  31. In sub-Saharan Africa, 45% of the rural population uses boreholes (BHs). Despite recent gains in improved water access and coverage, parallel use of unimproved sources persists. Periodic infrastructure disrepa...

    Authors: Olivia L. Schultes, Mustafa Sikder, Emmanuel A. Agyapong, Michelle O. Sodipo, Elena N. Naumova, Karen C. Kosinski and Alexandra V. Kulinkina
    Citation: BMC Research Notes 2022 15:114
  32. Clinicians worldwide struggle to identify the bacterial aetiology of bone and joint infections. Failure to unequivocally identify the pathogen is linked to poor clinical outcomes. We explored the added value o...

    Authors: Katja Wallander, Martin Vondracek and Christian G. Giske
    Citation: BMC Research Notes 2022 15:113
  33. Discrete but ordered covariates are quite common in applied statistics, and some regularized fitting procedures have been proposed for proper handling of ordinal predictors in statistical models. Motivated by ...

    Authors: Jan Gertheiss, Fabian Scheipl, Tina Lauer and Harald Ehrhardt
    Citation: BMC Research Notes 2022 15:112
  34. Canine lymphoma, the most common hematological cancer in dogs, shares many molecular and clinical characteristics with human Non-Hodgkin lymphoma (NHL). The standard treatment for canine lymphoma is “CHOP” mul...

    Authors: Miles W. Mee, Sydney Faulkner, Geoffrey A. Wood, J. Paul Woods, Dorothee Bienzle and Brenda L. Coomber
    Citation: BMC Research Notes 2022 15:111
  35. Mental health is a fundamental aspect in ensuring the stable and successful professional life of future physicians. Depressive symptoms can negatively affect the work-life-balance and efficiency at work of med...

    Authors: Katrin Dudo, Emilia Ehring, Stephan Fuchs, Sabine Herget, Stefan Watzke, Susanne Unverzagt and Thomas Frese
    Citation: BMC Research Notes 2022 15:109
  36. Musculoskeletal modeling and simulation are powerful research and education tools in engineering, neuroscience, and rehabilitation. Interactive musculoskeletal models (IMMs) can be controlled by muscle activit...

    Authors: Julia Manczurowsky, Mansi Badadhe and Christopher J. Hasson
    Citation: BMC Research Notes 2022 15:108
  37. The naked mole rats (NMRs, Heterocephalus glaber) are subterranean rodents that belong to the family Bathyergidae. They gained the attention of the scientific community for their exceptionally long lifespan of up...

    Authors: Kah-Ooi Chua, Iqra Fatima, Yin Yin Lau, Kar Wai Hong, Wai-Fong Yin, Andrei Mardaryev, Kok-Gan Chan and Chien-Yi Chang
    Citation: BMC Research Notes 2022 15:107
  38. Open science and open data within scholarly research programs are growing both in popularity and by requirement from grant funding agencies and journal publishers. A central component of open data management, ...

    Authors: Andrew Wright Child, Jennifer Hinds, Lucas Sheneman and Sven Buerki
    Citation: BMC Research Notes 2022 15:106
  39. Erucin (ERN), an isothiocyanate, is derived from the vegetable arugula. Although ERN has antitumor and antioxidant activity, the effect of ERN on osteoclast and osteoblast differentiation is not well documente...

    Authors: Tomohiro Takagi, Hirofumi Inoue, Shungo Fujii, Nobuyuki Takahashi and Mariko Uehara
    Citation: BMC Research Notes 2022 15:105
  40. Tamoxifen is considered to be the most widely used adjuvant therapy for hormone receptor positive breast cancer in premenopausal women. However, it is reported that nearly 30% of patients receiving tamoxifen t...

    Authors: Nadeeka Dimuthu Kumari Ranadeva, Nirmala Dushyanthi Sirisena, Tithila Kalum Wetthasinghe, Nafeesa Noordeen and Vajira Harshadeva Weerabaddana Dissanayake
    Citation: BMC Research Notes 2022 15:104

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