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  1. Snakes provide a unique vertebrate system for studying a diversity of extreme adaptations, including those related to development, metabolism, physiology, and venom. Despite their importance as research models...

    Authors: Todd A Castoe, Samuel E Fox, AP Jason de Koning, Alexander W Poole, Juan M Daza, Eric N Smith, Todd C Mockler, Stephen M Secor and David D Pollock

    Citation: BMC Research Notes 2011 4:310

    Content type: Research article

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  2. Cross-resistance to quinolones and beta-lactams is frequent in Enterobacteriaceae, due to the wide use of these antibiotics clinically and in the food industry. Prescription of one of these categories of antibiot...

    Authors: Thierry Frank, Jean R Mbecko, Pembe Misatou and Didier Monchy

    Citation: BMC Research Notes 2011 4:309

    Content type: Short Report

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  3. To preserve patient anonymity, health register data may be provided as binned data only. Here we consider as example, how to estimate mean survival time after a diagnosis of metastatic colorectal cancer from N...

    Authors: Henrik Støvring and Ivar S Kristiansen

    Citation: BMC Research Notes 2011 4:308

    Content type: Research article

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  4. Salmonella (S.) enterica is the main cause of salmonellosis in humans and animals. The epidemiology of this infection involves large geographical distances, and strains related to an episode of salmonellosis ther...

    Authors: Hélène van Cuyck, Alexandra Farbos-Granger, Philippe Leroy, Vuthy Yith, Bertrand Guillard, Jean Louis Sarthou, Jean Louis Koeck and Sun Lay Kruy

    Citation: BMC Research Notes 2011 4:306

    Content type: Research article

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  5. While the transcription of innate immunity genes in response to bacterial infection has been well-characterised in the Drosophila model, we recently demonstrated the capacity for such transcription to evolve i...

    Authors: Yixin H Ye and Elizabeth A McGraw

    Citation: BMC Research Notes 2011 4:305

    Content type: Short Report

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  6. To assist educators and researchers in improving the quality of medical research, we surveyed the editors and statistical reviewers of high-impact medical journals to ascertain the most frequent and critical s...

    Authors: Sara Fernandes-Taylor, Jenny K Hyun, Rachelle N Reeder and Alex HS Harris

    Citation: BMC Research Notes 2011 4:304

    Content type: Short Report

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  7. Apomixis, a natural form of asexual seed production in plants, is considered to have great biotechnological potential for agriculture. It has been hypothesised that de-regulation of the sexual developmental pa...

    Authors: Marco Pellino, Timothy F Sharbel, Martin Mau, Samuel Amiteye and José María Corral

    Citation: BMC Research Notes 2011 4:303

    Content type: Research article

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  8. The NAC transcription factor family is involved in the regulation of traits in both monocots and dicots of high agronomic importance. Understanding the precise functions of the NAC genes can be of utmost impor...

    Authors: Michael W Christiansen, Preben B Holm and Per L Gregersen

    Citation: BMC Research Notes 2011 4:302

    Content type: Research article

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  9. Body Mass Index (BMI), which is defined as the ratio between weight (in kg) and height (in m2), is often used in clinical practice as well as in large scale epidemiological studies to classify subjects as underwe...

    Authors: Bruno Federico, Filomena D'Aliesio, Fabio Pane, Giovanni Capelli and Angelo Rodio

    Citation: BMC Research Notes 2011 4:301

    Content type: Short Report

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  10. DNA methylation is a widespread epigenetic modification in vertebrate genomes. Genomic sites of DNA methylation can be bound by methyl-CpG-binding domain proteins (MBDs) and specific zinc finger proteins, whic...

    Authors: Ozren Bogdanović and Gert Jan C Veenstra

    Citation: BMC Research Notes 2011 4:300

    Content type: Technical Note

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  11. Dementia and cognitive impairment associated with aging are a major medical and social concern. Neuropsychological testing is a key element in the diagnostic procedures of Mild Cognitive Impairment (MCI), but ...

    Authors: João Maroco, Dina Silva, Ana Rodrigues, Manuela Guerreiro, Isabel Santana and Alexandre de Mendonça

    Citation: BMC Research Notes 2011 4:299

    Content type: Research article

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  12. Infertility is a major problem in sickle cell disease patients, especially in males. In addition to low serum testosterone, other abnormalities involving the accessory sex organs, such as the seminal vesicles ...

    Authors: Emmanuel K Abudu, Sulaiman A Akanmu, Oyetunji O Soriyan, Akinsegun A Akinbami, Adewumi Adediran, Titilope A Adeyemo and Charles C Okany

    Citation: BMC Research Notes 2011 4:298

    Content type: Research article

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  13. The use of the 2009 H1N1 vaccine has generated much debate concerning safety issues among the general population and physicians. It was questioned if this is a safe vaccine. Therefore, we investigated the safe...

    Authors: Harald Bias, David Quarcoo, Claus Meier-Wronski, Sabine Wicker, Joachim Seybold, Albert Nienhaus, David A Groneberg and Andres de Roux

    Citation: BMC Research Notes 2011 4:297

    Content type: Short Report

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  14. When detected, HIV can be effectively treated with antiretroviral therapy. Nevertheless in the U.S. approximately 25% of those who are HIV-infected do not know it. Much remains unknown about how to increase HI...

    Authors: D Keith McInnes, Jeffrey L Solomon, Barbara G Bokhour, Steven M Asch, David Ross, Kim M Nazi and Allen L Gifford

    Citation: BMC Research Notes 2011 4:295

    Content type: Short Report

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  15. CD99, a leukocyte surface glycoprotein, is broadly expressed in many cell types. On the cell surface, CD99 is expressed as two distinct isoforms, a long form and a short form. CD99 has been demonstrated to pla...

    Authors: Supansa Pata, Pavel Otáhal, Tomáš Brdička, Witida Laopajon, Kodchakorn Mahasongkram and Watchara Kasinrerk

    Citation: BMC Research Notes 2011 4:293

    Content type: Research article

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  16. In many developing countries, including Ethiopia, few have the skills to use data for effective decision making in public health. To address this need, the U.S. Centers for Disease Control and Prevention (CDC)...

    Authors: Italia V Rolle, Irum Zaidi, Jennifer Scharff, Donna Jones, Aynalem Firew, Fikre Enquselassie, Ashenafi Negash, Negussie Deyessa, Getnet Mitike, Nadine Sunderland and Peter Nsubuga

    Citation: BMC Research Notes 2011 4:292

    Content type: Short Report

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  17. The Taiwan Birth Panel Study (TBPS) is a prospective follow-up study to investigate the development of child health and disease in relation to in-utero and/or early childhood environmental exposures. The ratio...

    Authors: Chia-Jung Hsieh, Wu-Shiun Hsieh, Yi-Ning Su, Hua-Fang Liao, Suh-Fang Jeng, Feng-Ming Taso, Yaw-Huei Hwang, Kuen-Yuh Wu, Chia-Yang Chen, Yueliang Leon Guo and Pau-Chung Chen

    Citation: BMC Research Notes 2011 4:291

    Content type: Research article

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  18. The availability of genetic and genomic resources for melon has increased significantly, but functional genomics resources are still limited for this crop. TILLING is a powerful reverse genetics approach that ...

    Authors: Mireia González, Meihong Xu, Cristina Esteras, Cristina Roig, Antonio J Monforte, Christelle Troadec, Marta Pujol, Fernando Nuez, Abdelhafid Bendahmane, Jordi Garcia-Mas and Belén Picó

    Citation: BMC Research Notes 2011 4:289

    Content type: Research article

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  19. The advent of ChIP-seq technology has made the investigation of epigenetic regulatory networks a computationally tractable problem. Several groups have applied statistical computing methods to ChIP-seq dataset...

    Authors: Stephen A Hoang, Xiaojiang Xu and Stefan Bekiranov

    Citation: BMC Research Notes 2011 4:288

    Content type: Research article

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  20. Beta thalassemia is the most frequent genetic disorder of haemoglobin synthesis in Pakistan. Recurrent transfusions lead to iron-overload manifested by increased serum Ferritin levels, for which chelation ther...

    Authors: Haris Riaz, Talha Riaz, Muhammad Ubaid Khan, Sina Aziz, Faizan Ullah, Anis Rehman, Qandeel Zafar and Abdul Nafey Kazi

    Citation: BMC Research Notes 2011 4:287

    Content type: Short Report

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  21. Brucella epididymoorchitis(BEO) is a focal complication of human brucellosis and has been reported in 2-20% of patients with brucellosis. Brucellosis is an endemic disease in Iran. The incidence of the disease...

    Authors: Narges Najafi, Roya Ghassemian, Ali R Davoody and Atefe Tayebi

    Citation: BMC Research Notes 2011 4:286

    Content type: Short Report

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  22. Engaging all health care providers in tuberculosis (TB) control has been incorporated as an essential component of World Health Organization's Stop TB Strategy and the Stop TB Partnership's global plan 2006-20...

    Authors: Solomon A Yimer, Carol-Holm Hansen and Gunnar A Bjune

    Citation: BMC Research Notes 2011 4:285

    Content type: Research article

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  23. In intensive care, weaning is the term used for the process of withdrawal of mechanical ventilation to enable spontaneous breathing to be re-established. Inspiratory muscle weakness and deconditioning are comm...

    Authors: Lisa H Moodie, Julie C Reeve, Niki Vermeulen and Mark R Elkins

    Citation: BMC Research Notes 2011 4:283

    Content type: Project Note

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  24. Protein biomarker studies are currently hampered by a lack of measurement standards to demonstrate quality, reliability and comparability across multiple assay platforms. This is especially pertinent for immun...

    Authors: Susan Pang, Enamul S Ahsan, Hernan J Valdivia, Jesus Minguez and Carole A Foy

    Citation: BMC Research Notes 2011 4:281

    Content type: Short Report

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  25. Mycobacterial interspersed repetitive units - variable number of tandem repeats (MIRU-VNTR) genotyping is a powerful tool for unraveling clonally complex Mycobacterium tuberculosis (MTB) strains and detection of ...

    Authors: Lydia Nabyonga, David P Kateete, Fred A Katabazi, Paul R Odong, Christopher C Whalen, Katherine R Dickman and Joloba L Moses

    Citation: BMC Research Notes 2011 4:280

    Content type: Research article

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  26. Pleural tuberculosis (TB) diagnosis often requires invasive procedures such as pleural biopsy. The aim of this study was to evaluate the role of real-time polymerase chain reaction (PCR) for the IS 6110 sequence ...

    Authors: Franciele Rosso, Candice T Michelon, Rosa D Sperhacke, Mirela Verza, Liliane Olival, Marcus B Conde, Renata L Guerra, Arnaldo Zaha and Maria LR Rossetti

    Citation: BMC Research Notes 2011 4:279

    Content type: Short Report

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  27. Sensitivity to cold (hiesho) is a serious health problem in Japan, yet it is minimally understood within Western cultures. The purpose of this study was to clarify the divergence between pregnant Japanese woman l...

    Authors: Sachiyo Nakamura, Sueli MT Ichisato, Shigeko Horiuchi, Taeko Mori and Masako Momoi

    Citation: BMC Research Notes 2011 4:278

    Content type: Research article

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  28. Previous studies showed an inter-observer agreement for the NYHA classification of approximately 55%. The aim of this study was to calibrate the New York Heart Association (NYHA) classification system between ...

    Authors: Milton Severo, Rita Gaio, Patrícia Lourenço, Margarida Alvelos, Paulo Bettencourt and Ana Azevedo

    Citation: BMC Research Notes 2011 4:276

    Content type: Research article

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  29. At first 32 housekeeping genes were analyzed in six randomly chosen meningiomas, brain and dura mater using geNorm, NormFinder, Bestkeeper-1 software and the comparative ΔCt method. Reference genes were ranked...

    Authors: Christina Pfister, Marcos S Tatabiga and Florian Roser

    Citation: BMC Research Notes 2011 4:275

    Content type: Short Report

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  30. Acute surgery in the management of malignant colonic obstruction is associated with high morbidity and mortality. The use of self-expanding metal stents (SEMS) is an alternative method of decompressing colonic...

    Authors: Mattias Lepsenyi, Stefan Santen, Ingvar Syk, Jörgen Nielsen, Artur Nemeth, Ervin Toth and Henrik Thorlacius

    Citation: BMC Research Notes 2011 4:274

    Content type: Short Report

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  31. Anthrax has almost disappeared from mainland Europe, except for the Mediterranean region where cases are still reported. In Central and South Italy, anthrax is enzootic, but in the North there are currently no...

    Authors: Giuliano Garofolo, Luigina Serrecchia, Michela Corrò and Antonio Fasanella

    Citation: BMC Research Notes 2011 4:273

    Content type: Short Report

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  32. Metabolomics is a rapidly developing functional genomic tool that has a wide range of applications in diverse fields in biology and medicine. However, unlike transcriptomics and proteomics there is currently n...

    Authors: Julian L Griffin, Helen J Atherton, Christoph Steinbeck and Reza M Salek

    Citation: BMC Research Notes 2011 4:272

    Content type: Data Note

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  33. The aim of the present study was to investigate whether selenium levels differ between type 2 diabetic subjects with and without coronary artery disease (CAD).

    Authors: Alexios Sotiropoulos, Stavroula A Papadodima, Athanasia K Papazafiropoulou, Aggelos Ioannidis, Athanasia Kokkinari, Ourania Apostolou, Chara A Spiliopoulou and Sotirios Athanaselis

    Citation: BMC Research Notes 2011 4:270

    Content type: Research article

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  34. Tuberculosis is a major health problem in São Paulo, Brazil, which is the most populous and one of the most cosmopolitan cities in South America. To characterize the genetic diversity of Mycobacterium tuberculosi...

    Authors: Natália H Mendes, Fernando AF Melo, Adolfo CB Santos, José RC Pandolfi, Elisabete A Almeida, Rosilene F Cardoso, Henri Berghs, Suzana David, Faber K Johansen, Lívia G Espanha, Sergio RA Leite and Clarice QF Leite

    Citation: BMC Research Notes 2011 4:269

    Content type: Short Report

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  35. In 2009, an outbreak of dengue caused high fatality in Sri Lanka. We conducted 5 autopsies of clinically suspected myocarditis cases at the General Hospital, Peradeniya to describe the histopathology of the he...

    Authors: Kosala GAD Weerakoon, Senanayake AM Kularatne, Deepthika H Edussuriya, Sarachchandra KA Kodikara, Laxman PG Gunatilake, Vasanti G Pinto, Ashoka B Seneviratne and Sunethra Gunasena

    Citation: BMC Research Notes 2011 4:268

    Content type: Research article

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  36. In oral implantology, there is no consensus on the most appropriate regimen for antibiotics prescribing, the decision to prescribe antibiotic is usually based on procedure, patient and clinician related factor...

    Authors: Ashraf E AbuKaraky, Khaldoon Abu Afifeh, Adel A Khatib, Nadiajda O Khdairi, Hanan M Habarneh, Waleed KH Ahmad, Ahmad AS Hamdan and Faleh A Sawair

    Citation: BMC Research Notes 2011 4:266

    Content type: Short Report

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  37. Obtaining transcripts of homologs of closely related organisms and retrieving the reconstructed exon-intron patterns of the genes is a very important process during the analysis of the evolution of a protein f...

    Authors: Klas Hatje, Oliver Keller, Björn Hammesfahr, Holger Pillmann, Stephan Waack and Martin Kollmar

    Citation: BMC Research Notes 2011 4:265

    Content type: Research article

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  38. The database of sugarcane expressed sequence tags (EST) offers a great opportunity for developing molecular markers that are directly associated with important agronomic traits. The development of new EST-SSR ...

    Authors: Thiago G Marconi, Estela A Costa, Hercília RCAN Miranda, Melina C Mancini, Cláudio B Cardoso-Silva, Karine M Oliveira, Luciana R Pinto, Marcelo Mollinari, Antônio AF Garcia and Anete P Souza

    Citation: BMC Research Notes 2011 4:264

    Content type: Short Report

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  39. Chloroquine (CQ) is utilized as both cure and prophylaxis to Plasmodium infection. In animal studies, CQ administration to experimental animals is via intraperitoneal (i.p.) injection of a single dose that varies...

    Authors: Matthew D Lewis, Johannes Pfeil and Ann-Kristin Mueller

    Citation: BMC Research Notes 2011 4:262

    Content type: Project Note

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