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  1. The Health (Pricing and Supply of Medical Goods) Act 2013 passed into law in July 2013 and legislated for generic substitution in Ireland. The aim of the study was to ascertain the knowledge and perceptions of...

    Authors: A. O’Leary, C. Usher, M. Lynch, M. Hall, L. Hemeryk, S. Spillane, P. Gallagher and M. Barry
    Citation: BMC Research Notes 2015 8:790
  2. Shigellosis is recognized as a major global public health problem especially in developing countries particularly in children under-5 years of age. Therefore; the objective of this study was to determine the p...

    Authors: Atsebaha Gebrekidan Kahsay and Zelalem Teklemariam
    Citation: BMC Research Notes 2015 8:788
  3. Sedentary time is associated with obesity and is a risk factor for other adverse health outcomes. We examined how sedentary time and screen viewing (SV) behaviours in parents of young children are associated a...

    Authors: Lesley Wood, Russell Jago, Simon J. Sebire, Jesmond Zahra and Janice L. Thompson
    Citation: BMC Research Notes 2015 8:787
  4. Diabetes mellitus type 2 (T2D) is a chronic metabolic disease with a great impact on health status and quality of life (QoL) in terms of physical, social, and psychological well-being. The aim of the present s...

    Authors: Athanasia K. Papazafiropoulou, Florentia Bakomitrou, Aikaterini Trikallinou, Asimina Ganotopoulou, Chris Verras, George Christofilidis, Stavros Bousboulas and Αndreas Μelidonis
    Citation: BMC Research Notes 2015 8:786
  5. To be able to develop effective therapeutics for epidermolysis bullosa simplex (EBS), it is necessary to elucidate the molecular pathomechanisms that give rise to the disease’s characteristic severe skin-blist...

    Authors: Julia Herzog, Raphaela Rid, Martin Wagner, Harald Hundsberger, Andreas Eger, Johann Bauer and Kamil Önder
    Citation: BMC Research Notes 2015 8:785
  6. Deoxyuridine triphosphate nucleotidohydrolase (dUTPase) hydrolyzes dUTP to dUMP and pyrophosphate to maintain the cellular thymine-uracil ratio. dUTPase is also a target for cancer chemotherapy. However, the m...

    Authors: Noriko Inoguchi, Kittichai Chaiseeda, Mamoru Yamanishi, Moon Ki Kim, Yunho Jang, Mamta Bajaj, Catherine P. Chia, Donald F. Becker and Hideaki Moriyama
    Citation: BMC Research Notes 2015 8:784
  7. Endomyocardial fibrosis (EMF), the commonest restrictive cardiomyopathy worldwide, is characterized by inflammation and fibrosis of the endocardium. Inflammation in other parts of the body such as the peritone...

    Authors: Yvonne Brenda Nabunnya, James Kayima, Chris T. Longenecker, Richard A. Josephson and Juergen Freers
    Citation: BMC Research Notes 2015 8:783
  8. The hypothesis of an infectious etiology of the formerly named bronchiolo-alveolar carcinoma (BAC) has raised controversy. We investigated tumor lung tissues from five patients with former BAC histology using ...

    Authors: Nicolas Berthet, Lionel Frangeul, Ken André Olaussen, Elisabeth Brambilla, Nicolas Dorvault, Philippe Girard, Pierre Validire, Elie Fadel, Christiane Bouchier, Antoine Gessain and Jean-Charles Soria
    Citation: BMC Research Notes 2015 8:782
  9. Invasive amebiasis is not frequently seen in the United States. It is associated with considerable morbidity in patients residing in or traveling to endemic areas. We report a case series of patients with ameb...

    Authors: Rhonda Fleming, Chad J. Cooper, Ruben Ramirez-Vega, Ana Huerta-Alardin, Darius Boman and Marc J. Zuckerman
    Citation: BMC Research Notes 2015 8:781
  10. In 2013 the Netherlands faced a measles epidemic, during which more than 2600 individuals were infected, including 19 health care workers (HCW). Vaccinating health care workers can lead to benefits on both the...

    Authors: Stephanie Jessica Borggreve and Aura Timen
    Citation: BMC Research Notes 2015 8:780
  11. Intestinal helminths infect more than two billion people worldwide. They are common in developing countries where sanitary facilities are inadequate. There is scarcity of documented data on the magnitude of in...

    Authors: Bahiru Terefe, Endalew Zemene and Abdurehman E. Mohammed
    Citation: BMC Research Notes 2015 8:779
  12. No practical tests are currently available for screening vitamin B12 deficiency because the available techniques are invasive, expensive, and require a particular level of infrastructure and service that is no...

    Authors: Veena K. L. Karanth, Laxminarayan Karanth, Tulasi K. Karanth, Sowmyashree K. Karanth and Ragini Bekur
    Citation: BMC Research Notes 2015 8:778
  13. Previous genome-wide association studies have evaluated the impact of common genetic variants and identified several non-HLA risk loci associated with autoimmune liver diseases. More recent genome-wide associa...

    Authors: Kiyoshi Migita, Yuka Jiuchi, Hiroshi Furukawa, Minoru Nakamura, Atsumasa Komori, Michio Yasunami, Hideko Kozuru, Seigo Abiru, Kazumi Yamasaki, Shinya Nagaoka, Satoru Hashimoto, Shigemune Bekki, Kaname Yoshizawa, Masaaki Shimada, Hiroshi Kouno, Hiroshi Kamitsukasa…
    Citation: BMC Research Notes 2015 8:777
  14. Hypertension is a multifactorial disease caused by the interaction between genetic and environmental factors. Mutations in the methylenetetrahydrofolate reductase gene (MTHFR) have been known to be associated ...

    Authors: Sanaa Nassereddine, Yaya Kassogue, Farah Korchi, Rachida Habbal and Sellama Nadifi
    Citation: BMC Research Notes 2015 8:775
  15. Globally, 50,000–100,000 women develop obstetric fistula annually. At least 33,000 of these women live in Sub-Saharan Africa where limitations in quality obstetric care and fistula corrective repairs are preva...

    Authors: Tekle G. Egziabher, Ngoga Eugene, Karenzi Ben and Kateera Fredrick
    Citation: BMC Research Notes 2015 8:774
  16. With the approaching sunset on the Millennium Development Goals (MDGs), Tanzania continues with its final national push towards achievement of MDG #4 and MDG #5. The Mama Kwanza Socio-economic Health Initiati...

    Authors: Pammla Petrucka, Sandra Bassendowski, Marie Dietrich-Leurer, Cara Spence-Gress, Zenath Athuman and Joram Buza
    Citation: BMC Research Notes 2015 8:773
  17. Head and neck cancer (HNC) is one of the most common cancers worldwide and its incidence is reported to be increasing in resource-limited countries. There is a paucity of published data regarding head and neck...

    Authors: Japhet M. Gilyoma, Peter F. Rambau, Nestory Masalu, Neema M. Kayange and Phillipo L. Chalya
    Citation: BMC Research Notes 2015 8:772
  18. Organisms are subject to various stress conditions, which affect both the organism’s gene expression and phenotype. It is critical to understand microbial responses to stress conditions and uncover the underly...

    Authors: Niveda Sundararaman, Christine Ash, Weihua Guo, Rebecca Button, Jugroop Singh and Xueyang Feng
    Citation: BMC Research Notes 2015 8:771
  19. The four-dimensional symptom questionnaire (4DSQ) is an originally Dutch self-report questionnaire that has been developed in primary care to distinguish non-specific general distress from depression, anxiety ...

    Authors: V. S. Arnautov, D. V. Reyhart, A. B. Smulevich, N. N. Yakhno, B. Terluin, E. K. Zakharova, A. V. Andryushchenko, V. A. Parfenov, M. V. Zamergrad and D. V. Romanov
    Citation: BMC Research Notes 2015 8:770
  20. Delivery by skilled birth attendance serves as an indicator of progress towards reducing maternal mortality. In Ethiopia, the proportions of births attended by skilled personnel were very low 15 % and Oromia r...

    Authors: Tesfalidet Tekelab, Birhanu Yadecha and Alemu Sufa Melka
    Citation: BMC Research Notes 2015 8:769
  21. Severe hemophilia is an inherited, lifelong bleeding disorder characterized by spontaneous bleeding, which results in painful joint deformities. Currently two surgical treatments are available to treat haemoph...

    Authors: Marc Dauty, Raphael Gross, Fabien Leboeuf and Marc Trossaert
    Citation: BMC Research Notes 2015 8:768
  22. Regenerative medicine is strictly dependent on stem cells as a source for a high diversity of somatic cells. However, the isolation of such from individuals suffering from severe genetic skin blistering diseas...

    Authors: Markus Schosserer, Rita Reynoso, Verena Wally, Bogdan Jug, Viktoria Kantner, Sylvia Weilner, Ivana Buric, Johannes Grillari, Johann W. Bauer and Regina Grillari-Voglauer
    Citation: BMC Research Notes 2015 8:767
  23. Comprehensive multidisciplinary pulmonary rehabilitation is vital in the management of chronic obstructive pulmonary disease (COPD) and is considered for any stage of the disease. Rehabilitation programmes are...

    Authors: Tatjana M. Burkow, Lars K. Vognild, Elin Johnsen, Marijke Jongsma Risberg, Astrid Bratvold, Elin Breivik, Trine Krogstad and Audhild Hjalmarsen
    Citation: BMC Research Notes 2015 8:766
  24. Informed consent during medical practice is an essential component of comprehensive medical care and is a requirement that should be sought all the time the doctor interacts with the patients, though very chal...

    Authors: Joseph Ochieng, William Buwembo, Ian Munabi, Charles Ibingira, Haruna Kiryowa, Gabriel Nzarubara and Erisa Mwaka
    Citation: BMC Research Notes 2015 8:765
  25. Data on the frequency and awareness of cardiovascular risk factors in practicing doctors are lacking in Cameroon. This study reports on the prevalence of cardiovascular risk factors in primary care physicians ...

    Authors: Ahmadou M. Jingi and Jean Jacques N. Noubiap
    Citation: BMC Research Notes 2015 8:762
  26. In the last decade canine models have been used extensively to study genetic causes of neurological disorders such as epilepsy and Alzheimer’s disease and unravel their pathophysiological pathways. Reverse tra...

    Authors: Quirine E. M. Stassen, Frank M. Riemers, Hannah Reijmerink, Peter A. J. Leegwater and Louis C. Penning
    Citation: BMC Research Notes 2015 8:761
  27. The objective of this study was to evaluate the appropriateness of antibiotic suspensions use for pediatrics among Palestinian mothers’ including their reconstitution, dose administration, duration, and storag...

    Authors: Rowa’ J. Al-Ramahi, Abd Al Naser Zaid and Haya Anabousi
    Citation: BMC Research Notes 2015 8:760
  28. Many plant polysaccharides have shown high antioxidant and immunostimulating properties and can be explored as novel molecules with biological properties that can potentially improve immune function. The objec...

    Authors: Thaddée Boudjeko, Rosette Megnekou, Alice Louise Woguia, Francine Mediesse Kegne, Judith Emery Kanemoto Ngomoyogoli, Christiane Danielle Nounga Tchapoum and Olga Koum
    Citation: BMC Research Notes 2015 8:759
  29. Pheochromocytoma is a neuroendocrine tumor that predominantly presents with hypertension, palpitations, and tachycardia due to excessive catecholamine excretion. Although pheochromocytoma multisystem crisis (P...

    Authors: Katsura Kakoki, Yasuyoshi Miyata, Youhei Shida, Tomoaki Hakariya, Kosuke Takehara, Seiya Izumida, Motohiro Sekino, Naoe Kinoshita, Tsukasa Igawa, Junya Fukuoka and Hideki Sakai
    Citation: BMC Research Notes 2015 8:758
  30. Male injecting drug users drove the onset of the HIV epidemic in Indonesia but over time more women have been diagnosed. We examined the relative proportion of female patients in an HIV cohort and characterize...

    Authors: Annisa Rahmalia, Rudi Wisaksana, Hinta Meijerink, Agnes R. Indrati, Bachti Alisjahbana, Nel Roeleveld, Andre J. A. M. van der Ven, Marie Laga and Reinout van Crevel
    Citation: BMC Research Notes 2015 8:757
  31. Over time, the circumstances encountered in case of child mistreatment, can be quite complex and then, can lead to methodological questions for the analysis of the data. Based on data coming from 395 children ...

    Authors: Christelle Senterre, Alain Levêque, Brigitte Vanthournout and Michèle Dramaix
    Citation: BMC Research Notes 2015 8:756
  32. Formalin has been widely used by pathology laboratories. Its carcinogenicity has led researchers to explore formalin substitutes. Streck Cell Preservative (SCP) is a formalin-free preservative that can preserv...

    Authors: Jianbing Qin, Jennifer N. Sanmann, Jeff S. Kittrell, Pamela A. Althof, Erin E. Kaspar and Bradford A. Hunsley
    Citation: BMC Research Notes 2015 8:755
  33. Next-generation transcriptome sequencing (RNA-Seq) has become the standard practice for studying gene splicing, mutations and changes in gene expression to obtain valuable, accurate biological conclusions. How...

    Authors: Rajandas Heera, Parimannan Sivachandran, Suresh V. Chinni, Joanne Mason, Larry Croft, Manickam Ravichandran and Lee Su Yin
    Citation: BMC Research Notes 2015 8:754
  34. Sri Lanka has a high prevalence of type 2 diabetes mellitus. Energy and macronutrient intakes of diabetic patients have not been previously studied in this population. We aimed to clarify the energy and nutrie...

    Authors: Arjuna Medagama, Devaka Fernando and Heshan Widanapathirana
    Citation: BMC Research Notes 2015 8:753
  35. Participant recruitment in clinical trials is often challenging. Building partnerships with healthcare organizations during proposal development facilitates access to the community and may influence its subseq...

    Authors: Mirjam M. Garvelink, Adriana Freitas, Matthew Menear, Nathalie Brière, Dawn Stacey and France Légaré
    Citation: BMC Research Notes 2015 8:751
  36. Recent studies have shown that certain human genetic polymorphisms could be associated with susceptibility to tuberculosis (TB) infection and disease. Advances in next generation sequencing include the ability...

    Authors: Carla Duncan, Frances Jamieson and Carolina Mehaffy
    Citation: BMC Research Notes 2015 8:750
  37. The influences that different programs and conditions have on error rates of single-nucleotide polymorphism (SNP) analyses are poorly understood. Using Illumina short-read sequence data generated from Listeria mo...

    Authors: Arthur W. Pightling, Nicholas Petronella and Franco Pagotto
    Citation: BMC Research Notes 2015 8:748
  38. Toxoplasmosis was recently included as a neglected disease by the Center for Disease Control. Ocular toxoplasmosis is one clinical presentation of congenital or acquired infection. The laboratory diagnosis is ...

    Authors: Mariana Previato, Fábio Batista Frederico, Fernando Henrique Antunes Murata, Rubens Camargo Siqueira, Amanda Pires Barbosa, Aparecida Perpétuo Silveira-Carvalho, Cristina da Silva Meira, Vera Lúcia Pereira-Chioccola, Ricardo Gava, Plínio Pereira Martins Neto, Luiz Carlos de Mattos and Cinara Cássia Brandão de Mattos
    Citation: BMC Research Notes 2015 8:746
  39. We have conducted this study to examine the clinical and morphological pattern of brain arteriovenous malformations (BAVMs) along with their treatment and short term outcome in a tertiary care hospital in Bang...

    Authors: Ahmed Hossain Chowdhury, Sharif Uddin Khan, Kazi Mohibur Rahman, A. T. M. Hasibul Hasan, Swapon Kumar Ghose, Badrul Haque, Mansur Habib and Quazi Deen Mohammad
    Citation: BMC Research Notes 2015 8:745
  40. Student-led teaching has long been regarded as a useful ancillary educational method. It is also a valuable tool in the development of aspects of professionalism in student tutors and contributes to a sense of...

    Authors: Antonia J. Clarke, Annette Burgess, Audrey Menezes and Craig Mellis
    Citation: BMC Research Notes 2015 8:743
  41. Military personnel are high-risk people for parenteral and sexually transmitted diseases such as hepatitis B virus (HBV) and hepatitis C virus (HCV). Data regarding HBV and HCV prevalence among military person...

    Authors: Tigist Birku, Baye Gelaw, Feleke Moges and Abate Assefa
    Citation: BMC Research Notes 2015 8:737
  42. Hyacinth macaw Anodorhynchus hyacinthinus is the largest parrot of the world and is considered vulnerable to extinction due to its habitat loss and illegal trade associated to the international pet market demand....

    Authors: Helder E. da Silva, Flavia T. Presti, Adriane P. Wasko and Danillo Pinhal
    Citation: BMC Research Notes 2015 8:736

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