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  1. Endothelin-1 plays an important role in the pathogenesis of severe pulmonary hypertension. The + 139 ‘A’, adenine insertion variant in 5′UTR of edn1 gene has been reported to be associated with increased expressi...

    Authors: Abhishek Kumar, Minati Choudhury, Sakshi Dhingra Batra, Kriti Sikri and Anushree Gupta

    Citation: BMC Research Notes 2021 14:194

    Content type: Research note

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  2. Equivocal association the contribution of 25-hydroxyvitamin D (25(OH)D) and the well-accepted role of vitamin D-binding protein (VDBP) on bioavailability of 25(OH)D or its independent roles, has led to possibl...

    Authors: Leila Setayesh, Krista Casazza, Nariman Moradi, Sanaz Mehranfar, Habib Yarizadeh, Abbas Amini, Mir Saeed Yekaninejad and Khadijeh Mirzaei

    Citation: BMC Research Notes 2021 14:193

    Content type: Research note

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  3. MG-63 cells that have osteoblastic and adipogenic differentiation potential were evaluated for internalization, and adipogenic differentiation in the presence and absence of the covalently functionalized aryl ...

    Authors: Muhammad Abdulwahab, Amir Ali Khan, Sallam Hasan Abdallah, Muhammad Nasir Khan Khattak, Bizuneh Workie, Mohamed Mehdi Chehimi and Ahmed Ali Mohamed

    Citation: BMC Research Notes 2021 14:192

    Content type: Research note

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  4. The naked mole rat (NMR) (Heterocephalus glaber) is increasingly considered an important biomedical research model for various conditions like hypoxic brain injury, cancer and nociception. This study was designed...

    Authors: R. M. Mwobobia, T. I. Kanui and K. S. P. Abelson

    Citation: BMC Research Notes 2021 14:191

    Content type: Research note

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  5. Enhancing financial protection in health is one of the main goals of Iran’s health transformation program (HTP), a recent reform conducted in early 2014. This study aimed to measure financial protection using ...

    Authors: Ali Darvishi, Mostafa Amini-Rarani, Mohammad Hossein Mehrolhassani and Vahid Yazdi-Feyzabadi

    Citation: BMC Research Notes 2021 14:190

    Content type: Research note

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  6. The SARS-CoV-2 pandemic has prompted one of the most extensive and expeditious genomic sequencing efforts in history. Each viral genome is accompanied by a set of metadata which supplies important information ...

    Authors: Landen Gozashti and Russell Corbett-Detig

    Citation: BMC Research Notes 2021 14:189

    Content type: Research note

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  8. Ultraviolet radiation is known for its antimicrobial properties but unfortunately, it could also harm humans. Currently, disinfection techniques against SARS-CoV-2 are being sought that can be applied on air a...

    Authors: Petra Vatter, Katharina Hoenes and Martin Hessling

    Citation: BMC Research Notes 2021 14:187

    Content type: Research note

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  9. African ancestry seems to be a risk factor for hypertension; however, few genetic studies have addressed this issue. This study aimed to investigate the prevalence of polymorphisms NOS3; rs1799983, IGFBP3; rs1197...

    Authors: Abel Barbosa Lira Neto, Nancy Borges Rodrigues Vasconcelos, Tamara Rodrigues dos Santos, Luisa Elvira Cavazzani Duarte, Monica Lopes Assunção, Carolinne de Sales-Marques and Haroldo da Silva Ferreira

    Citation: BMC Research Notes 2021 14:186

    Content type: Research note

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  10. Obesity and insulin resistance (IR) are interrelated in a range of ways. The IR-obesity relationship is not a cause-and-effect association. Molecular biology research has made tremendous strides in discovering...

    Authors: Faezeh Abaj, Said Abdul Ghafour Saeedy and Khadijeh Mirzaei

    Citation: BMC Research Notes 2021 14:185

    Content type: Research note

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  12. Lactate has been shown to be preferentially metabolized in comparison to glucose after physiological stress, such as strenuous exercise. Derangements of lactate and glucose are common after out-of-hospital car...

    Authors: Pedro Freire Jorge, Rohan Boer, Rene A. Posma, Katharina C. Harms, Bart Hiemstra, Bas W. J. Bens and Maarten W. Nijsten

    Citation: BMC Research Notes 2021 14:183

    Content type: Research note

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  13. Insects are the most evolutionarily successful groups of organisms, and this success is largely due to their flight ability. Interestingly, some stick insects have lost their flight ability despite having wing...

    Authors: Takuma Sakamoto, Shunya Sasaki, Nobuki Yamaguchi, Miho Nakano, Hiroki Sato, Kikuo Iwabuchi, Hiroko Tabunoki, Richard J. Simpson and Hidemasa Bono

    Citation: BMC Research Notes 2021 14:182

    Content type: Research note

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  14. Pearl millet (Pennisetum glaucum) is a staple cereal crop for semi-arid regions. Its whole genome sequence and deduced putative gene sequences are available. However, the functions of many pearl millet genes are ...

    Authors: Daisuke Tsugama and Tetsuo Takano

    Citation: BMC Research Notes 2021 14:181

    Content type: Data note

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  16. The double burden of malnutrition is an emerging public health concern nowadays which a correlation with obesity. This study aimed to examine the relationship between resting metabolic rate (RMR) and dietary i...

    Authors: Seyedeh Forough Sajjadi, Atieh Mirzababaei, Afsoun Abdollahi, Farideh Shiraseb and Khadijeh Mirzaei

    Citation: BMC Research Notes 2021 14:179

    Content type: Research note

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  17. The ongoing Coronavirus disease 2019 (COVID-19) pandemic has drastically impacted the global health and economy. Computed tomography (CT) is the prime imaging modality for diagnosis of lung infections in COVID...

    Authors: Shokouh Shakouri, Mohammad Amin Bakhshali, Parvaneh Layegh, Behzad Kiani, Farid Masoumi, Saeedeh Ataei Nakhaei and Sayyed Mostafa Mostafavi

    Citation: BMC Research Notes 2021 14:178

    Content type: Data note

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  18. To compare the live birth rates (LBR) and neonatal outcomes of frozen cycle in vitro fertilization (IVF) with fresh cycle IVF in the Indonesian population.

    Authors: Wiryawan Permadi, Hartanto Bayuaji, Kevin Dominique Tjandraprawira, Dian Tjahyadi, Harris Harlianto, Yanni Melliandari Achmad, Nanang Winarto Astarto and Tono Djuwantono

    Citation: BMC Research Notes 2021 14:177

    Content type: Research note

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  19. This randomised controlled trial (RCT) aimed to investigate the effects of a simple cognitive task intervention on intrusive memories ("flashbacks") and associated symptoms following a traumatic event. Patient...

    Authors: Marie Kanstrup, Laura Singh, Katarina E. Göransson, Beau Gamble, Rod S. Taylor, Lalitha Iyadurai, Michelle L. Moulds and Emily A. Holmes

    Citation: BMC Research Notes 2021 14:176

    Content type: Research note

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  20. To characterize the bacterial community of Wind Cave’s Madison aquifer through whole-genome sequencing, and to better understand the bacterial ecology by identifying genes involved in acyl-homoserine lactone (...

    Authors: Peter C. Wengert, Narayan H. Wong, Hazel A. Barton, Han Ming Gan, André O. Hudson and Michael A. Savka

    Citation: BMC Research Notes 2021 14:175

    Content type: Research note

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  22. Dall’s sheep (Ovis dalli dalli) are important herbivores in the mountainous ecosystems of northwestern North America, and recent declines in some populations have sparked concern. Our aim was to improve capabilit...

    Authors: Kelly E. Williams, Damian M. Menning, Eric J. Wald, Sandra L. Talbot, Kumi L. Rattenbury and Laura R. Prugh

    Citation: BMC Research Notes 2021 14:173

    Content type: Data note

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  23. To determine the general and genotype-specific prevalence of HPV and to identify potential risk factors for the infection in a population-based screening of Peruvian women.

    Authors: Juana del Valle-Mendoza, Lorena Becerra-Goicochea, Miguel Angel Aguilar-Luis, Luis Pinillos-Vilca, Hugo Carrillo-Ng, Wilmer Silva-Caso, Carlos Palomares-Reyes, Andre-Alonso Taco-Masias, Ronald Aquino-Ortega, Carmen Tinco-Valdez, Yordi Tarazona-Castro, Cynthia-Wendy Sarmiento-Ramirez and Luis J. del Valle

    Citation: BMC Research Notes 2021 14:172

    Content type: Research note

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  24. Physical activity has been shown to improve quality of life in cancer patients with some evidence in multiple myeloma. This study aimed to determine myeloma patients’ exercise levels, their perception of physi...

    Authors: Catherine S. Y. Lecat, Orla McCourt, Joanne Land, Kwee Yong and Abigail Fisher

    Citation: BMC Research Notes 2021 14:171

    Content type: Research note

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  25. Here, we present the first record of stable colonies of the South American fur seal (Arctocephalus australis), in an area where their presence has never been documented (hereafter distribution gap), as well as an...

    Authors: Daniel Cárcamo, Marlene Pizarro, Muriel Orellana, Anahi Canto, Pablo Herrera, Lily Muñoz, Piera Vásquez-Calderón, Alicia Guerrero, Maritza Sepúlveda, L. René Durán and Doris Oliva

    Citation: BMC Research Notes 2021 14:170

    Content type: Research note

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  26. Uncoupling protein 2 (UCP2) plays a crucial role in energy homeostasis via insulin secretion regulation, free fatty acid concentrations, and lipid metabolism. This study aimed to investigate the association of...

    Authors: Saleheh rezapour, Shiva Ahdi khosroshahi, Hadi Farajnia, Fatemeh Mohseni, Manouchehr Khoshbaten and Safar Farajnia

    Citation: BMC Research Notes 2021 14:169

    Content type: Research note

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  27. The impact of the current COVID-19 pandemic has been felt worldwide. Many vulnerable populations rely heavily on peer support provided by individual or collaborative groups. This study aimed to evaluate the im...

    Authors: Julie McMullan, Ashleen L. Crowe, Caitlin Bailie and Amy Jayne McKnight

    Citation: BMC Research Notes 2021 14:168

    Content type: Data note

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  28. Hospital data are a useful resource for studying pregnancy complications, including bleeding-related conditions, however, the reliability of these data is unclear. This study aims to examine reliability of rep...

    Authors: Heather J. Baldwin, Tanya A. Nippita, Siranda Torvaldsen, Therese M. McGee, Kristen Rickard and Jillian A. Patterson

    Citation: BMC Research Notes 2021 14:167

    Content type: Research note

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  29. To compare the accuracy of heart rate detection properties of a novel, wireless, dry-electrode electrocardiogram (ECG) device, NeoBeat®, to that of a conventional 3-lead gel-electrode ECG monitor (PropaqM®) in...

    Authors: Hanne Pike, Joar Eilevstjønn, Peder Bjorland, Jørgen Linde, Hege Ersdal and Siren Rettedal

    Citation: BMC Research Notes 2021 14:166

    Content type: Research note

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  31. Microplates are ubiquitous in biological research because they make it easy to collect data for hundreds of different conditions in a single experiment. Despite this, there is no standard method to annotate th...

    Authors: Kale Kundert

    Citation: BMC Research Notes 2021 14:164

    Content type: Research note

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  32. The aim of the current study was to assess prevalence of Toxoplasma infection and its associated risk factors in women of childbearing-age in central Iran.

    Authors: Melica Shahighi, Aliehsan Heidari, Hossein Keshavarz, Amir Bairami, Saeedeh Shojaee, Monireh Sezavar, Mahboobeh Salimi and Aref Teimouri

    Citation: BMC Research Notes 2021 14:163

    Content type: Research note

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  34. The aim of this study was to design a domestic water temperature, pH and turbidity monitoring system that could constantly log temperature, pH and turbidity of water and give alerts in case the parameters are ...

    Authors: Diana Rita Nanyanzi, Gilbert Gilibrays Ocen, Timothy Omara, Felix Bwire, Davis Matovu and Twaibu Semwogerere

    Citation: BMC Research Notes 2021 14:161

    Content type: Research note

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  35. Previously we observed that maternal multiple micronutrient supplementation in pregnancy was associated with increased offspring size at birth and adiposity, as well as with maternal gestational diabetes risk,...

    Authors: Clive J. Petry, Ken K. Ong, Ieuan A. Hughes and David B. Dunger

    Citation: BMC Research Notes 2021 14:160

    Content type: Research note

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  36. Participation in physical activity and sports is known to have positive implications for physical health, and for social and emotional wellbeing of children. Following corrective spinal surgery for scoliosis, ...

    Authors: Leanne R. Willson, Madeline Klootwyk, Laura G. Rogers, Kathleen Shearer, Sarah Southon and Christina Sasseville

    Citation: BMC Research Notes 2021 14:159

    Content type: Research note

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  37. Psychological problems associated with isolation and mistrust are common among young adults with autism spectrum disorder (ASD). Schema therapy (ST) has recently been shown to be effective against chronic pers...

    Authors: Fumiyo Oshima, Tomokazu Murata, Toshiyuki Ohtani, Mikuko Seto and Eiji Shimizu

    Citation: BMC Research Notes 2021 14:158

    Content type: Research note

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  38. Cardiac regeneration in the axolotl has been found to rely on the innate immune system, and especially macrophages have been demonstrated to play a vital role in regulating the regenerative process. In this st...

    Authors: Kathrine Pedersen, Rikke Kongsgaard Rasmussen, Anita Dittrich and Henrik Lauridsen

    Citation: BMC Research Notes 2021 14:157

    Content type: Research note

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  39. Gut-microbiota plays key roles in many aspects like the health and illness of humans. It's well proved that modification of gut microbiota by probiotics is useful for improving inflammatory bowel disease (IBD)...

    Authors: Sheyda Damoogh, Mehrad Vosough, Shima Hadifar, Masoumeh Rasoli, Ali Gorjipour, Sarvenaz Falsafi and Ava Behrouzi

    Citation: BMC Research Notes 2021 14:156

    Content type: Research note

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  41. Ribonucleic acids (RNA) are involved in many cellular functions. In general, RNA is made up by only four different ribonucleotides. The modifications of RNA (epitranscriptome) can greatly enhance the structura...

    Authors: Hongzhou Wang, Jennifer H. Simpson, Madison E. Kotra, Yuanting Zhu, Saumya Wickramasinghe, David A. Mills and Norman H. L. Chiu

    Citation: BMC Research Notes 2021 14:154

    Content type: Research note

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  42. Tree legume species play an important role in forest restoration in the tropics. Understanding how different species adjust carbohydrate allocation and growth under distinct nutrient availability will enhance ...

    Authors: Roberto K. Jaquetti and José Francisco C. Gonçalves

    Citation: BMC Research Notes 2021 14:153

    Content type: Data note

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  43. Herd immunity is achieved when in a population, immune individuals are in a sufficiently large proportion. Neutralizing antibodies specific to SARS-CoV-2 that are produced following infection or vaccination ar...

    Authors: Amandine Mveang Nzoghe, Marielle Leboueny, Eliane Kuissi Kamgaing, Anicet Christel Maloupazoa Siawaya, Eliode Cyrien Bongho, Ofilia Mvoundza Ndjindji, Guy-Stephan Padzys, Bénédicte Ndeboko, Simon Ategbo and Joel Fleury Djoba Siawaya

    Citation: BMC Research Notes 2021 14:152

    Content type: Research note

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  44. The purpose of the present study was to investigate the antimicrobial susceptibility pattern, biofilm production, and the presence of biofilm genes among the S. maltophilia clinical isolates. A total of 85 clinic...

    Authors: Narjess Bostanghadiri, Abdollah Ardebili, Zohreh Ghalavand, Samane Teymouri, Mahsa Mirzarazi, Mehdi Goudarzi, Ehsan Ghasemi and Ali Hashemi

    Citation: BMC Research Notes 2021 14:151

    Content type: Research note

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  45. In this study we compare the amino acid and codon sequence of SARS-CoV-2, SARS-CoV and MERS-CoV using different statistics programs to understand their characteristics. Specifically, we are interested in how d...

    Authors: Jung Eun Huh, Seunghee Han and Taeseon Yoon

    Citation: BMC Research Notes 2021 14:150

    Content type: Research note

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  46. Deep extubation refers to endotracheal extubation performed while a patient is deeply anesthetized and without airway reflexes. After deep extubation, patients are sent to the post-anesthesia care unit (PACU) ...

    Authors: Jeremy Juang, Martha Cordoba, Mark Xiao, Alex Ciaramella, Jeremy Goldfarb, Jorge Enrique Bayter and Alvaro Andres Macias

    Citation: BMC Research Notes 2021 14:149

    Content type: Research note

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  48. Breast cancer (BC) is one of the most common diseases in women globally, with an increasing number of deaths associated with it. Recently the role of polymorphisms in the genes encoding cytokines and immune ce...

    Authors: Hadi Rezaeean, Gholam Abbas Kaydani, Najmaldin Saki, Sasan Razmjoo, Maryam Labibzadeh and Hamid Yaghooti

    Citation: BMC Research Notes 2021 14:147

    Content type: Research note

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  49. This study aimed to identify novel genetic variants in the CR2 extracellular domain of the epidermal growth factor receptor (EGFR) in healthy individuals and patients with six different types of adenocarcinoma...

    Authors: Maryam Marzouq, Ali Nairouz, Noureddine Ben Khalaf, Sonia Bourguiba-Hachemi, Raed Quaddorah, Dana Ashoor and M. Dahmani Fathallah

    Citation: BMC Research Notes 2021 14:146

    Content type: Research note

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  50. Identifying orthology relationships among sequences is essential to understand evolution, diversity of life and ancestry among organisms. To build alignments of orthologous sequences, phylogenomic pipelines of...

    Authors: Mick Van Vlierberghe, Hervé Philippe and Denis Baurain

    Citation: BMC Research Notes 2021 14:143

    Content type: Data note

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