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  1. The proposed candidate gene underlying the Malus fusca fire blight resistance locus on chromosome 10 was previously predicted to possess 880 amino acids and 8 exons. Eight base pair (8 bp) insertion/deletion in t...

    Authors: Ofere Francis Emeriewen, Henryk Flachowsky and Andreas Peil

    Citation: BMC Research Notes 2021 14:291

    Content type: Research note

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  2. Four-dimensional flow CMR allows for a comprehensive assessment of the blood flow kinetic energy of the ventricles of the heart. In comparison to standard two-dimensional image acquisition, 4D flow CMR is felt...

    Authors: Ciaran Grafton-Clarke, Saul Crandon, Jos J. M. Westenberg, Peter P. Swoboda, John P. Greenwood, Rob J. van der Geest, Andrew J. Swift, Vassilios S. Vassiliou, Sven Plein and Pankaj Garg

    Citation: BMC Research Notes 2021 14:289

    Content type: Data note

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  3. In a previous study we demonstrated that the occurrence of sexual jokes in the class was associated with higher levels of psychological health complaints. Building on and extending these findings, the aim of t...

    Authors: Sara Brolin Låftman, Ylva Bjereld, Bitte Modin and Petra Löfstedt

    Citation: BMC Research Notes 2021 14:288

    Content type: Research note

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  4. The aim of this study is to qualitatively investigate the lived experiences of mental health among frontline health workers providing COVID-19-realted care in Uganda. This study provides insights into the cont...

    Authors: Choolwe Muzyamba, Ogylive Makova and Geofrey Samukulu Mushibi

    Citation: BMC Research Notes 2021 14:286

    Content type: Research note

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  5. Extracellular histones have been identified as one molecular factor that can cause and sustain alveolar damage and were linked to high mortality rates in critically ill patients. In this pilot study, we wanted...

    Authors: Robert Ruemmler, Alexander Ziebart, Elisabeth Britten, Moritz Gosling, Rene Rissel and Erik K. Hartmann

    Citation: BMC Research Notes 2021 14:285

    Content type: Research note

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  6. Restless Legs Syndrome (RLS) is commonly known to cause morbidity in patients on hemodialysis, making them prone to chronic mental health illnesses such as depression and anxiety, and also adversely impact qua...

    Authors: Mahjabeen Yaseen, Furqan Ahmad Jarullah, Sadia Yaqoob, Hassan Abdullah Shakeel, Hamza Maqsood and Sadiq Naveed

    Citation: BMC Research Notes 2021 14:284

    Content type: Research note

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  7. The purpose of this clinical trial was to examine the effect of omega-3 fatty acids (W-3 FAs), nanocurcumin and their combination on serum levels and gene expression of VCAM in patients with episodic migraine.

    Authors: Mina Abdolahi, Elmira Karimi, Payam Sarraf, Abbas Tafakhori, Goli Siri, Farahnaz Salehinia, Mohsen Sedighiyan, Behzad Asanjarani, Mostafa Badeli, Hamed Abdollahi, Niyoosha Yoosefi, Abolghasem yousefi, Amir Shayegan rad and Mahmoud Djalali

    Citation: BMC Research Notes 2021 14:283

    Content type: Research note

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  8. In order to assess the applicability of a direct-to-consumer (DTC) genetic testing to translational research for obtaining new knowledge on relationships between drug target genes and diseases, we examined pos...

    Authors: Masahiro Inoue, Shota Arichi, Tsuyoshi Hachiya, Anna Ohtera, Seok-Won Kim, Eric Yu, Masatoshi Nishimura, Kazuhito Shiosakai and Takeshi Ohira

    Citation: BMC Research Notes 2021 14:282

    Content type: Research note

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  9. Eritrea is the most frequent country of origin among asylum seekers in Switzerland. On their journey through the desert and across the Mediterranean Sea, Eritrea refugees are often exposed to traumatizing expe...

    Authors: Afona Chernet, Nicole Probst-Hensch, Véronique Sydow, Daniel H. Paris and Niklaus D. Labhardt

    Citation: BMC Research Notes 2021 14:281

    Content type: Research note

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  10. The present population-based study aimed to examine the association of chronic stress and sleeping difficulties with self-reported irritable bowel syndrome (IBS), gastrointestinal (GI) symptoms past 2 weeks, a...

    Authors: Jasmin Zejnelagic and Bodil Ohlsson

    Citation: BMC Research Notes 2021 14:280

    Content type: Research note

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  11. The associations between dietary carbohydrate, fat intake, and inflammation are controversial. Most existing data are from industrialized societies which low-carbohydrate and high-fat diet is common and so the...

    Authors: Elmira Karimi, Habib Yarizadeh, Leila Setayesh, Seyyedeh Forough Sajjadi, Nasim Ghodoosi, Leil Khorraminezhad and Khadijeh Mirzaei

    Citation: BMC Research Notes 2021 14:279

    Content type: Research note

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  12. Mediastinal schwannomas are sometimes confused with other neoplasms during initial radiological studies, especially when there is a history of cancer in another area. In these cases, a more accurate analysis u...

    Authors: Ramiro Sandoval-Macias, Irving Daniel Ortiz-Sanchez, Ana Lilia Remirez-Castellanos, Luis Mora-Hernandez, Candelaria Cordova-Uscanga, Alejandra Mantilla-Morales, Tania Alejandra Galindo-Garcia, Armando Gamboa-Dominguez and Fernando Candanedo-Gonzalez

    Citation: BMC Research Notes 2021 14:278

    Content type: Research note

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  13. Strengthening the organizational agility of the hospital can lead to decreased production costs and increased market share, better serving to patients' needs, introduction of new services and increased competi...

    Authors: Zahra Kavosi, Sajad Delavari, Mohammad Mehdi Kiani, Peivand Bastani, Mohebat Vali and Marzieh Salehi

    Citation: BMC Research Notes 2021 14:277

    Content type: Research note

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  14. Marginalised populations are less likely to take part in health research, and are sometimes considered ‘easy to ignore’. We aimed to describe our approach and results of recruiting parents who experience disad...

    Authors: Louise Tully, Eleni Spyreli, Virginia Allen-Walker, Karen Matvienko-Sikar, Sheena McHugh, Jayne Woodside, Michelle C. McKinley, Patricia M. Kearney, Moira Dean, Catherine Hayes, Caroline Heary and Colette Kelly

    Citation: BMC Research Notes 2021 14:276

    Content type: Research note

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  15. Food frequency questionnaires are widely used as a dietary assessment tool in nutritional epidemiology to determine the relationship between diet and diseases. In Tanzania, there are several cultural variation...

    Authors: Ahmed Gharib Khamis, Akwilina Wendelin Mwanri, Julius Edward Ntwenya, Mbazi Senkoro, Katharina Kreppel, Bassirou Bonfoh, Sayoki Godfrey Mfinanga and Gideon Kwesigabo

    Citation: BMC Research Notes 2021 14:274

    Content type: Research note

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  16. Visualisation methods, primarily color-coded representation of sequence data, have been a predominant means of representation of DNA data. Algorithmic conversion of DNA sequence data to sound—sonification—repr...

    Authors: Heleen Plaisier, Thomas R. Meagher and Daniel Barker

    Citation: BMC Research Notes 2021 14:273

    Content type: Research note

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  17. The COVID-19 pandemic has brought about a major upheaval in the lives of older adults and their family/friend caregivers, including those utilizing home care services. In this article, we focus on results from...

    Authors: Lori E. Weeks, Sue Nesto, Bradley Hiebert, Grace Warner, Wendy Luciano, Kathleen Ledoux and Lorie Donelle

    Citation: BMC Research Notes 2021 14:271

    Content type: Research note

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  18. Canine visceral leishmaniasis (CVL) is the main source of human visceral leishmaniosis (HVL) in Mediterranean region, including Iran and is spread from domestic dogs to Phlebotomine sand flies vectors to humans. ...

    Authors: Yonas Yimam Ayene, Mehdi Mohebali, Homa Hajjaran, Behnaz Akhoundi, Saeedeh Shojaee, Abbas Rahimi-Foroushani, Mohammad Javad Abbaszadeh Afshar and Z. Zarei

    Citation: BMC Research Notes 2021 14:270

    Content type: Research note

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  19. Sulfation is an essential physiological process that regulates the function of a wide array of molecules involved in brain development. We have previously shown expression levels for the sulfate transporter Slc13...

    Authors: Tracey J. Harvey, Raul Ayala Davila, Diana Vidovic, Sazia Sharmin, Michael Piper and David G. Simmons

    Citation: BMC Research Notes 2021 14:269

    Content type: Data note

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  20. The “Integrating a neonatal healthcare package for Malawi” (IMCHA#108030) project conducted mixed-methods to understand facility-based implementation factors for newborn health innovations in low-resourced hea...

    Authors: Mai-Lei Woo Kinshella, Alinane Linda Nyondo-Mipando, Queen Dube, David M. Goldfarb and Kondwani Kawaza

    Citation: BMC Research Notes 2021 14:267

    Content type: Data note

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  21. To find mutations that may have recently occurred in Plum pox virus (PPV), we collected six PPV-infected plum/peach trees from the western part of Japan and one from the eastern part. After sequencing the full-le...

    Authors: Tomoaki Mori, Chiaki Warner, Serika Ohno, Koichi Mori, Takamasa Tobimatsu and Takashi Sera

    Citation: BMC Research Notes 2021 14:266

    Content type: Research note

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  22. This study aimed to investigate the short-term effect of ovariohysterectomy on urine levels of serotonin and its relation to levels of cortisol, testosterone and progesterone in female dogs. Seven bitches were...

    Authors: Eva Hydbring-Sandberg, Elin Larsson, Andrzej Madej and Odd Viking Höglund

    Citation: BMC Research Notes 2021 14:265

    Content type: Research note

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  23. Malaria is a major global health concern with the urgent need for new treatment alternatives due to the alarming increase of drug-resistant Plasmodium strains. Chalcones and its derivatives are important pharmaco...

    Authors: Shweta Sinha, Ajay Prakash, Bikash Medhi, Alka Sehgal, Daniela I. Batovska and Rakesh Sehgal

    Citation: BMC Research Notes 2021 14:264

    Content type: Research note

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  24. There has been much discussion and debate around the underreporting of COVID-19 infections and deaths in India. In this short report we first estimate the underreporting factor for infections from publicly ava...

    Authors: Soumik Purkayastha, Ritoban Kundu, Ritwik Bhaduri, Daniel Barker, Michael Kleinsasser, Debashree Ray and Bhramar Mukherjee

    Citation: BMC Research Notes 2021 14:262

    Content type: Research note

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  25. Sengon (Falcataria moluccana) is a popular tree species in community plantation forests in Java, Indonesia due to its fast-growing and multipurpose characteristics. However, without effective control measures sen...

    Authors: Ulfah J. Siregar, Aditya Nugroho, Hasyyati Shabrina, Fitri Indriani, Apriliya Damayanti and Deden D. Matra

    Citation: BMC Research Notes 2021 14:261

    Content type: Data note

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  26. Pediatric acute lymphoblastic leukemia (ALL) is the most prevalent type of cancer among children. This study was conducted to describe and correlate the clinical characteristics and outcomes of treatment of pa...

    Authors: Ramzi Shawahna, Sultan Mosleh, Yahya Odeh, Rami Halawa and Majd Al-Ghoul

    Citation: BMC Research Notes 2021 14:259

    Content type: Research note

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  27. This study was conducted to evaluate the effect of the Iran’s Health Transformation Plan on the frequency of natural vaginal deliveries (NVDs), cesarean sections (CSs), and total deliveries in the Fars provinc...

    Authors: Farhad Lotfi, Saeed Lohivash, Zahra Kavosi, Sakine Owjimehr and Mohsen Bayati

    Citation: BMC Research Notes 2021 14:257

    Content type: Research note

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  28. Human precision cut lung slices (PCLS) are widely used as an ex vivo model system for drug discovery and development of new therapies. PCLS reflect the functional heterogeneity of lung tissue and possess relev...

    Authors: Monika Niehof, Stella Marie Reamon-Buettner, Olga Danov, Tanja Hansen and Katherina Sewald

    Citation: BMC Research Notes 2021 14:255

    Content type: Research note

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  29. Psoriasis is an immune-mediated inflammatory skin disease. It can involve any body skin area, particularly the scalp, lower back, elbows, and knees. There are several topical and systemic therapies for the tre...

    Authors: Alireza Yargholi, Leila Shirbeigi, Roja Rahimi, Parvin Mansouri and Mohammad Hossein Ayati

    Citation: BMC Research Notes 2021 14:253

    Content type: Research note

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  30. The purpose of this study is to compare the prevalence of latent TB infection (LTBI) among patients with type-2 diabetes mellitus (T2DM) to healthy controls without T2DM. To achieve this objective, we conducte...

    Authors: Argita D. Salindri, J. Sonya Haw, Genet A. Amere, Joyce T. Alese, Guillermo E. Umpierrez and Matthew J. Magee

    Citation: BMC Research Notes 2021 14:252

    Content type: Research note

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  31. Dengue viral infection is an ongoing epidemic in Sri Lanka, causing significant mortality and morbidity. A descriptive-analytical study was carried out using serologically confirmed Dengue patients during a 6 ...

    Authors: Dickowita Kankanamge Dilani Priyangika, Gayani Premawansa, Madura Adikari, Sharmila Thillainathan, Sunil Premawansa, Bernard Deepal Wanniarachchi Jayamanne and Ranjan Premaratna

    Citation: BMC Research Notes 2021 14:251

    Content type: Research note

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  32. This study was designed to explore the patterns of financial incentives received by some frontline health workers (including nurses, midwives as well as community health workers in paid employment) and the imp...

    Authors: Ekechi Okereke, George Eluwa, Akinwumi Akinola, Ibrahim Suleiman, Godwin Unumeri and Sylvia Adebajo

    Citation: BMC Research Notes 2021 14:250

    Content type: Research note

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  33. This research was aimed to isolate cellulolytic molds in empty fruit bunches of oil palm (EFBOP) and soils from palm oil plantation area and identify their enzyme activities to digest EFBOP.

    Authors: Tracy Miller, Diana Elizabeth Waturangi and Tresnawati Purwadaria

    Citation: BMC Research Notes 2021 14:249

    Content type: Research note

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  34. Turn sections represent the second largest part of total race time in 1500 m freestyle races and may substantially affect race results. Therefore, the aim of the study was to investigate individual race strate...

    Authors: Marek Polach, Dan Thiel, Jan Kreník and Dennis-Peter Born

    Citation: BMC Research Notes 2021 14:248

    Content type: Research note

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  35. A novel 3-gene host transcriptional signature (GBP5, DUSP3 and KLF2) has been validated for tuberculosis (TB) treatment monitoring using laboratory-based RNA sequencing platforms. The signature was recently trans...

    Authors: Alexandra J. Zimmer, Samuel G. Schumacher, Erik Södersten, Anna Mantsoki, Romain Wyss, David H. Persing, Sara Banderby, Linda Strömqvist Meuzelaar, Jacqueline Prieto, Devasena Gnanashanmugam, Purvesh Khatri, Stefano Ongarello, Morten Ruhwald and Claudia M. Denkinger

    Citation: BMC Research Notes 2021 14:247

    Content type: Research note

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  36. Chloroquine is used as a conventional drug therapy for the treatment of malaria. The existence of resistance to chloroquine shown among various species of Plasmodium leads to the search for more efficacious thera...

    Authors: Eshani Mahajan, Shweta Sinha, Alka Bhatia, Rakesh Sehgal and Bikash Medhi

    Citation: BMC Research Notes 2021 14:246

    Content type: Research note

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  37. Glutathione S-transferases have been associated with experimental resistance to some drugs. The present study investigated the factors associated with blood pressure control in patients with essential hyperten...

    Authors: Herman Karim Sombié, Daméhan Tchelougou, Abdoul Karim Ouattara, Jonas Koudougou Kologo, Pegdwendé Abel Sorgho, Dogfunianalo Somda, Sakinata Yaméogo, Arsène Wendpagnangdé Zongo, Isabelle Touwendpoulimdé Kiendrebeogo, Enagnon Tiémoko Herman Donald Adoko, Albert Théophane Yonli, Florencia Wendkuuni Djigma, Patrice Zabsonré, Hassanata Millogo and Jacques Simporé

    Citation: BMC Research Notes 2021 14:244

    Content type: Research note

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  38. The Delta-Notch signaling pathway induces fine-grained patterns of differentiation from initially homogeneous progenitor cells in many biological contexts, including Drosophila bristle formation, where mathematic...

    Authors: Masaharu Yoshihara, Teppei Nishino, Manoj Kumar Yadav, Akihiro Kuno, Takeshi Nagata, Hiroyasu Ando and Satoru Takahashi

    Citation: BMC Research Notes 2021 14:243

    Content type: Research note

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  39. This study evaluated the relationship between rheumatoid arthritis (RA) disease activity level and physical activity (PA) by using an accelerometer and self-reported questionnaire.

    Authors: Yoichi Toyoshima, Nobuyuki Yajima, Tetsuya Nemoto, Osamu Namiki and Katsunori Inagaki

    Citation: BMC Research Notes 2021 14:242

    Content type: Research note

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