Lecker SH, Solomon V, Mitch WE, Goldberg AL: Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states. J Nutr. 1999, 129: 227S-237S.
PubMed
CAS
Google Scholar
Tisdale MJ: Mechanisms of cancer cachexia. Physiol Rev. 2009, 89: 381-410. 10.1152/physrev.00016.2008.
Article
PubMed
CAS
Google Scholar
Debigare R, Cote CH, Maltais F: Peripheral muscle wasting in chronic obstructive pulmonary disease. Clinical relevance and mechanisms. Am J Respir Crit Care Med. 2001, 164: 1712-1717.
Article
PubMed
CAS
Google Scholar
Anker SD, Ponikowski P, Varney S, Chua TP, Clark AL, Webb-Peploe KM, Harrington D, Kox WJ, Poole-Wilson PA, Coats AJ: Wasting as independent risk factor for mortality in chronic heart failure. Lancet. 1997, 349: 1050-1053. 10.1016/S0140-6736(96)07015-8.
Article
PubMed
CAS
Google Scholar
Marquis K, Debigaré R, Lacasse Y, LeBlanc P, Jobin J, Carrier G, Maltais F: Midthigh muscle cross-sectional area is a better predictor of mortality than body mass index in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2002, 166: 809-813. 10.1164/rccm.2107031.
Article
PubMed
Google Scholar
Murphy KT, Lynch GS: Update on emerging drugs for cancer cachexia. Expert Opin Emerg Drugs. 2009, 14: 619-632. 10.1517/14728210903369351.
Article
PubMed
CAS
Google Scholar
Glass DJ: Signalling pathways that mediate skeletal muscle hypertrophy and atrophy. Nat Cell Biol. 2003, 5: 87-90. 10.1038/ncb0203-87.
Article
PubMed
CAS
Google Scholar
Sandri M: Signaling in muscle atrophy and hypertrophy. Physiology (Bethesda). 2008, 23: 160-170. 10.1152/physiol.00041.2007.
Article
CAS
Google Scholar
Bodine SC, Latres E, Baumhueter S, Lai VK, Nunez L, Clarke BA, Poueymirou WT, Panaro FJ, Na E, Dharmarajan K, Pan ZQ, Valenzuela DM, DeChiara TM, Stitt TN, Yancopoulos GD, Glass DJ: Identification of ubiquitin ligases required for skeletal muscle atrophy. Science. 2001, 294: 1704-1708. 10.1126/science.1065874.
Article
PubMed
CAS
Google Scholar
Leger B, Cartoni R, Praz M, Lamon S, Deriaz O, Crettenand A, Gobelet C, Rohmer P, Konzelmann M, Luthi F, Russell AP: Akt signalling through GSK-3beta, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy. J Physiol. 2006, 576: 923-933. 10.1113/jphysiol.2006.116715.
Article
PubMed
CAS
PubMed Central
Google Scholar
Doucet M, Russell AP, Léger B, Debigaré R, Joanisse DR, Caron MA, LeBlanc P, Maltais F: Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2007, 176: 261-269. 10.1164/rccm.200605-704OC.
Article
PubMed
CAS
Google Scholar
Bergstrom J: Muscle electrolytes in man. Determined by neutron activation analysis on needle biopsy specimens. A study on normal subjects, kidney patients, and patients with chronic diarrhaea. Scand J Clin Lab Invest. 1962, 14: 110-
Google Scholar
Deldicque L, Atherton P, Patel R, Theisen D, Nielens H, Rennie MJ, Francaux M: Decrease in Akt/PKB signalling in human skeletal muscle by resistance exercise. Eur J Appl Physiol. 2008, 104: 57-65. 10.1007/s00421-008-0786-7.
Article
PubMed
CAS
Google Scholar
Fujita S, Dreyer HC, Drummond MJ, Glynn EL, Cadenas JG, Yoshizawa F, Volpi E, Rasmussen BB: Nutrient signalling in the regulation of human muscle protein synthesis. J Physiol. 2007, 582: 813-823. 10.1113/jphysiol.2007.134593.
Article
PubMed
CAS
PubMed Central
Google Scholar
Whittom F, Jobin J, Simard PM, Leblanc P, Simard C, Bernard S, Belleau R, Maltais F: Histochemical and morphological characteristics of the vastus lateralis muscle in patients with chronic obstructive pulmonary disease. Med Sci Sports Exerc. 1998, 30: 1467-1474. 10.1097/00005768-199810000-00001.
Article
PubMed
CAS
Google Scholar
Charette SJ, Lambert H, Nadeau PJ, Landry J: Protein quantification by chemiluminescent Western blotting: elimination of the antibody factor by dilution series and calibration curve. J Immunol Methods. 2010, 353: 148-150. 10.1016/j.jim.2009.12.007.
Article
PubMed
CAS
Google Scholar
Rasband WS: ImageJ, U.S. National Institutes of Health. Bethesda, Maryland, USA. 1997, [http://rsbinfonihgov/ij/]
Google Scholar
Sui L, Anderson WL, Gilbert ME: Impairment in short-term but enhanced long-term synaptic potentiation and ERK activation in adult hippocampal area CA1 following developmental thyroid hormone insufficiency. Toxicol Sci. 2005, 85: 647-656. 10.1093/toxsci/kfi095.
Article
PubMed
CAS
Google Scholar
Du K, Tsichlis PN: Regulation of the Akt kinase by interacting proteins. Oncogene. 2005, 24: 7401-7409. 10.1038/sj.onc.1209099.
Article
PubMed
CAS
Google Scholar
Crossland H, Constantin-Teodosiu D, Gardiner SM, Constantin D, Greenhaff PL: A potential role for Akt/FOXO signalling in both protein loss and the impairment of muscle carbohydrate oxidation during sepsis in rodent skeletal muscle. J Physiol. 2008, 586: 5589-5600. 10.1113/jphysiol.2008.160150.
Article
PubMed
CAS
PubMed Central
Google Scholar
Medina EA, Afsari RR, Ravid T, Castillo SS, Erickson KL, Goldkorn T: Tumor necrosis factor-{alpha} decreases Akt protein levels in 3T3-L1 adipocytes via the caspase-dependent ubiquitination of Akt. Endocrinology. 2005, 146: 2726-2735. 10.1210/en.2004-1074.
Article
PubMed
CAS
Google Scholar
Lecker SH, Jagoe RT, Gilbert A, Gomes M, Baracos V, Bailey J, Price SR, Mitch WE, Goldberg AL: Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression. FASEB J. 2004, 18: 39-51. 10.1096/fj.03-0610com.
Article
PubMed
CAS
Google Scholar
Huang LE, Gu J, Schau M, Bunn HF: Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway. Proc Natl Acad Sci USA. 1998, 95: 7987-7992. 10.1073/pnas.95.14.7987.
Article
PubMed
CAS
PubMed Central
Google Scholar
Koyama S, Hata S, Witt CC, Ono Y, Lerche S, Ojima K, Chiba T, Doi N, Kitamura F, Tanaka K, Abe K, Witt SH, Rybin V, Gasch A, Franz T, Labeit S, Sorimachi H: Muscle RING-finger protein-1 (MuRF1) as a connector of muscle energy metabolism and protein synthesis. J Mol Biol. 2008, 376: 1224-1236. 10.1016/j.jmb.2007.11.049.
Article
PubMed
CAS
Google Scholar
Greenhaff PL, Karagounis LG, Peirce N, Simpson EJ, Hazell M, Layfield R, Wackerhage H, Smith K, Atherton P, Selby A, Rennie MJ: Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle. Am J Physiol Endocrinol Metab. 2008, 295: E595-604. 10.1152/ajpendo.90411.2008.
Article
PubMed
CAS
PubMed Central
Google Scholar
Cohen S, Brault JJ, Gygi SP, Glass DJ, Valenzuela DM, Gartner C, Latres E, Goldberg AL: During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation. J Cell Biol. 2009, 185: 1083-1095. 10.1083/jcb.200901052.
Article
PubMed
CAS
PubMed Central
Google Scholar
Plaisance I, Morandi C, Murigande C, Brink M: TNF-alpha increases protein content in C2C12 and primary myotubes by enhancing protein translation via the TNF-R1, PI3K, and MEK. Am J Physiol Endocrinol Metab. 2008, 294: E241-50.
Article
PubMed
CAS
Google Scholar
Chibalin AV, Yu M, Ryder JW, Song XM, Galuska D, Krook A, Wallberg-Henriksson H, Zierath JR: Exercise-induced changes in expression and activity of proteins involved in insulin signal transduction in skeletal muscle: differential effects on insulin-receptor substrates 1 and 2. Proc Natl Acad Sci USA. 2000, 97: 38-43. 10.1073/pnas.97.1.38.
Article
PubMed
CAS
PubMed Central
Google Scholar
Agouni A, Owen C, Czopek A, Mody N, Delibegovic M: In vivo differential effects of fasting, re-feeding, insulin and insulin stimulation time course on insulin signaling pathway components in peripheral tissues. Biochem Biophys Res Commun. 2010, 401: 104-111. 10.1016/j.bbrc.2010.09.018.
Article
PubMed
CAS
Google Scholar