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  1. The actual impact of the pandemic on COVID-19 specific mortality is still unclear due to the variability in access to diagnostic tools. This study aimed to estimate the excess all-cause mortality in Iran until...

    Authors: Seyed Amir Ahmad Safavi-Naini, Yeganeh Farsi, Walid Q. Alali, Ali Solhpour and Mohamad Amin Pourhoseingholi
    Citation: BMC Research Notes 2022 15:130
  2. Journal peer review regulates the flow of ideas through an academic discipline and thus has the power to shape what a research community knows, actively investigates, and recommends to policymakers and the wid...

    Authors: Alexandru Marcoci, Ans Vercammen, Martin Bush, Daniel G. Hamilton, Anca Hanea, Victoria Hemming, Bonnie C. Wintle, Mark Burgman and Fiona Fidler
    Citation: BMC Research Notes 2022 15:127
  3. ‘Candidatus Liberibacter asiaticus’ (CLas) is associated with the devastating citrus ‘greening’ disease. All attempts to achieve axenic growth and complete Koch’s postulates with CLas have failed to date, at best...

    Authors: Lulu Cai, Mukesh Jain, Alejandra Munoz-Bodnar, Jose C. Huguet-Tapia and Dean W. Gabriel
    Citation: BMC Research Notes 2022 15:125
  4. To design and construct a new synthetic nanobody library using a structure-based approach that seeks to maintain high protein stability and increase the number of functional variants within the combinatorial s...

    Authors: Ernesto Moreno, Mario S. Valdés-Tresanco, Andrea Molina-Zapata and Oliberto Sánchez-Ramos
    Citation: BMC Research Notes 2022 15:124
  5. The aim of this study is to determine the metabolic impact of a nutrition education program on metabolic parameters and the presence of metabolic syndrome (MetS).

    Authors: Quintí Foguet-Boreu, Mireia Vilamala-Orra, Cristina Vaqué-Crusellas, Pere Roura-Poch, Montse Assens Tauste, Judit Bori Vila, Jose Manuel Santos-López and Ruben del Río Sáez
    Citation: BMC Research Notes 2022 15:122
  6. How do birds navigate their way? It is one of the interesting question about homing pigeons, however the genetic of navigation has reminded as a puzzle. Optic lobe, olfactory bulb, hippocampus and cere were co...

    Authors: Hamed Kharrati-Koopaee, Ali Esmailizadeh and Fatemeh Sabahi
    Citation: BMC Research Notes 2022 15:121
  7. Due to the increase of type 2 diabetes (T2D), the number of patients in treatment with multiple anti-diabetic agents is increased. According to the recent recommendation of treatment guidelines, sodium-glucose...

    Authors: Makoto Fujiwara, Masaru Shimizu, Yuko Maejima and Kenju Shimomura
    Citation: BMC Research Notes 2022 15:120
  8. A clinical trial carried out in patients hospitalized for clinical and surgical conditions. This study evaluated the effectiveness of text messaging interventions (TM) versus telephone counseling (TC) to promo...

    Authors: Lígia Menezes do Amaral, Telmo Mota Ronzani, Erica Cruvinel, Kimber Richter, Rafaela de Oliveira Andrade, Isabella Oliveira Lanzieri, Ângela Caroline Dias Albino Destro de Macêdo and Isabel Cristina Gonçalves Leite
    Citation: BMC Research Notes 2022 15:119
  9. It remains unclear that the relationship between sprint and/or endurance performance and salivary immunological factors and stress hormones in athletes. The aim of this study was to investigate if salivary imm...

    Authors: Masataka Uchida, Tadashi Suga, Masafumi Terada and Tadao Isaka
    Citation: BMC Research Notes 2022 15:118
  10. This study was aimed to assess the enzymatic activity and pathogenicity potential of Beauveria bassiana and Metarhizium anisopliae against whiteflies in Ethiopia.

    Authors: Amha Gebremariam, Yonas Chekol and Fassil Assefa
    Citation: BMC Research Notes 2022 15:117
  11. Increasingly, policies are being introduced to reward and recognise open research practices, while the adoption of such practices into research routines is being facilitated by many grassroots initiatives. How...

    Authors: Olivia S. Kowalczyk, Alexandra Lautarescu, Elisabet Blok, Lorenza Dall’Aglio and Samuel J. Westwood
    Citation: BMC Research Notes 2022 15:116
  12. The redbanded stink bug (RBSB), Piezodorus guildinii (Hemiptera: Pentatomidae), is native to the Caribbean Basin and is currently considered an invasive pest in Florida, Louisiana, Mississippi, and Texas in the s...

    Authors: Surya Saha, K. Clint Allen, Lukas A. Mueller, Gadi V. P. Reddy and Omaththage P. Perera
    Citation: BMC Research Notes 2022 15:115
  13. In sub-Saharan Africa, 45% of the rural population uses boreholes (BHs). Despite recent gains in improved water access and coverage, parallel use of unimproved sources persists. Periodic infrastructure disrepa...

    Authors: Olivia L. Schultes, Mustafa Sikder, Emmanuel A. Agyapong, Michelle O. Sodipo, Elena N. Naumova, Karen C. Kosinski and Alexandra V. Kulinkina
    Citation: BMC Research Notes 2022 15:114
  14. Clinicians worldwide struggle to identify the bacterial aetiology of bone and joint infections. Failure to unequivocally identify the pathogen is linked to poor clinical outcomes. We explored the added value o...

    Authors: Katja Wallander, Martin Vondracek and Christian G. Giske
    Citation: BMC Research Notes 2022 15:113
  15. Discrete but ordered covariates are quite common in applied statistics, and some regularized fitting procedures have been proposed for proper handling of ordinal predictors in statistical models. Motivated by ...

    Authors: Jan Gertheiss, Fabian Scheipl, Tina Lauer and Harald Ehrhardt
    Citation: BMC Research Notes 2022 15:112
  16. Canine lymphoma, the most common hematological cancer in dogs, shares many molecular and clinical characteristics with human Non-Hodgkin lymphoma (NHL). The standard treatment for canine lymphoma is “CHOP” mul...

    Authors: Miles W. Mee, Sydney Faulkner, Geoffrey A. Wood, J. Paul Woods, Dorothee Bienzle and Brenda L. Coomber
    Citation: BMC Research Notes 2022 15:111
  17. Mental health is a fundamental aspect in ensuring the stable and successful professional life of future physicians. Depressive symptoms can negatively affect the work-life-balance and efficiency at work of med...

    Authors: Katrin Dudo, Emilia Ehring, Stephan Fuchs, Sabine Herget, Stefan Watzke, Susanne Unverzagt and Thomas Frese
    Citation: BMC Research Notes 2022 15:109
  18. Musculoskeletal modeling and simulation are powerful research and education tools in engineering, neuroscience, and rehabilitation. Interactive musculoskeletal models (IMMs) can be controlled by muscle activit...

    Authors: Julia Manczurowsky, Mansi Badadhe and Christopher J. Hasson
    Citation: BMC Research Notes 2022 15:108
  19. The naked mole rats (NMRs, Heterocephalus glaber) are subterranean rodents that belong to the family Bathyergidae. They gained the attention of the scientific community for their exceptionally long lifespan of up...

    Authors: Kah-Ooi Chua, Iqra Fatima, Yin Yin Lau, Kar Wai Hong, Wai-Fong Yin, Andrei Mardaryev, Kok-Gan Chan and Chien-Yi Chang
    Citation: BMC Research Notes 2022 15:107
  20. Open science and open data within scholarly research programs are growing both in popularity and by requirement from grant funding agencies and journal publishers. A central component of open data management, ...

    Authors: Andrew Wright Child, Jennifer Hinds, Lucas Sheneman and Sven Buerki
    Citation: BMC Research Notes 2022 15:106
  21. Erucin (ERN), an isothiocyanate, is derived from the vegetable arugula. Although ERN has antitumor and antioxidant activity, the effect of ERN on osteoclast and osteoblast differentiation is not well documente...

    Authors: Tomohiro Takagi, Hirofumi Inoue, Shungo Fujii, Nobuyuki Takahashi and Mariko Uehara
    Citation: BMC Research Notes 2022 15:105
  22. Tamoxifen is considered to be the most widely used adjuvant therapy for hormone receptor positive breast cancer in premenopausal women. However, it is reported that nearly 30% of patients receiving tamoxifen t...

    Authors: Nadeeka Dimuthu Kumari Ranadeva, Nirmala Dushyanthi Sirisena, Tithila Kalum Wetthasinghe, Nafeesa Noordeen and Vajira Harshadeva Weerabaddana Dissanayake
    Citation: BMC Research Notes 2022 15:104
  23. To describe postpartum depression and associated risk factors among postpartum patients in the United States (US) between February and July 2020. This study used a cross-sectional descriptive design to collect...

    Authors: Clayton J. Shuman, Alex F. Peahl, Neha Pareddy, Mikayla E. Morgan, Jolyna Chiangong, Philip T. Veliz and Vanessa K. Dalton
    Citation: BMC Research Notes 2022 15:102
  24. In a study of potential prostate cancer therapeutics, glycerol was used to increase the density of one solution. Glycerol alone was therefore one of the controls. Tumors of human PC3 castrate-resistant prostat...

    Authors: Ariel DeGuzman, Mary Y. Lorenson and Ameae M. Walker
    Citation: BMC Research Notes 2022 15:101
  25. Nicotine replacement therapy (NRT) helps people stop smoking. Monitoring treatment adherence is important as poor adherence to NRT limits its effectiveness. As e-cigarettes contain nicotine, their use (‘vaping...

    Authors: Yue Huang, Joanne Emery, Felix Naughton, Sue Cooper, Lisa McDaid, Anne Dickinson, Miranda Clark, Darren Kinahan-Goodwin, Ross Thomson, Lucy Phillips, Sarah Lewis, Sophie Orton and Tim Coleman
    Citation: BMC Research Notes 2022 15:100
  26. Adaptive laboratory evolution (ALE) is an effective approach to study the evolution behavior of bacterial cultures and to select for strains with desired metabolic features. In this study, we explored the poss...

    Authors: Jyotshana Gautam, Hui Xu, Junxi Hu, Christa Pennacchio, Anna Lipzen, Joel Martin and Zhaohui Xu
    Citation: BMC Research Notes 2022 15:99
  27. The rapid progress in sequencing technology and related bioinformatics tools aims at disentangling diversity and conservation issues through genome analyses. The foremost challenges of the field involve coping...

    Authors: Nelina Angelova, Theodoros Danis, Jacques Lagnel, Costas S. Tsigenopoulos and Tereza Manousaki
    Citation: BMC Research Notes 2022 15:98
  28. Currently, the only available staging criterion for T. b. rhodesiense requires a lumber puncture to collect and later examine cerebrospinal fluid (CSF). This study examined the potential of plasma Neuron-Specific...

    Authors: Charles D. Kato, Dorothy Twesigye, Vincent P. Alibu, Ann Nanteza, Julius Nsubuga, Claire M. Mugasa and Enock Matovu
    Citation: BMC Research Notes 2022 15:97
  29. Miscarriages affect 10% of women aged 25–29, and 53% of women over 45. The primary cause of miscarriage is aneuploidy that originated in eggs. The Aurora kinase family has three members that regulate chromosom...

    Authors: Caroline Kratka, David Drutovic, Cecilia S. Blengini and Karen Schindler
    Citation: BMC Research Notes 2022 15:96
  30. Assessing amniotic fluid determines an important dimension of fetal health. Significant relationships of oligohydramnios, which occurs in 1–2% of pregnancies, with abnormal pregnancy outcomes such as intrauter...

    Authors: Fatemeh Azarkish, Roksana Janghorban, Shirin Bozorgzadeh, Abedeh Arzani, Rahemeh Balouchi and Mahnaz Didehvar
    Citation: BMC Research Notes 2022 15:95
  31. Nipple-related complications are major factors that prevent breastfeeding for many new mothers. Hence, we tested the effects of aloe arborescens fomentation applied to the nipples as a treatment for nipple-rel...

    Authors: Yumiko Tateoka
    Citation: BMC Research Notes 2022 15:94
  32. Laser pointers are common teaching tools used during lessons. The pointing precision may influence the teaching effectiveness. In this study, we examined the effect of four external factors, namely aiming dist...

    Authors: Choi Yeung Andy Tse, Pui Wah Kong, Jun Jie Poh and Daniel T. P. Fong
    Citation: BMC Research Notes 2022 15:93
  33. The dosage of levothyroxine (LT4) during pregnancy differs among different ethnic groups worldwide. These differences are due to variations in geographical iodine distribution, autoimmunity, and variations in ...

    Authors: Zareen Kiran, Wardah Khalid, Aisha Sheikh and Najmul Islam
    Citation: BMC Research Notes 2022 15:92
  34. Diacerein inhibits the synthesis and activity of pro-inflammatory cytokines, decreases macrophage infiltration in adipose tissue and thus increases insulin sensitivity and signalling. We conducted this study t...

    Authors: Jintanan Jangsiripornpakorn, Sasima Srisuk, Laor Chailurkit, Hataikarn Nimitphong, Sunee Saetung and Boonsong Ongphiphadhanakul
    Citation: BMC Research Notes 2022 15:91
  35. The COVID-19 pandemic has forced many human subjects research to halt in-person activities and pivot to virtual engagement, including Focus Groups (FGs). We highlight learnings from our experience of hosting v...

    Authors: Helen Lindau, Francisco Ramos-Gomez, Jeremiah Garza, Tracy Finlayson, Morgan Pareja, Jenny Liu and Stuart Gansky
    Citation: BMC Research Notes 2022 15:90
  36. The Hybrid Assistive Limb (HAL) has recently been used to treat movement disorders. Although studies have shown its effectiveness for chronic myelopathy, the immediate effects of HAL gait training on lower lim...

    Authors: Shigeki Kubota, Hideki Kadone, Yukiyo Shimizu, Masao Koda, Hiroshi Takahashi, Kousei Miura, Fumihiko Eto, Takeo Furuya, Yoshiyuki Sankai and Masashi Yamazaki
    Citation: BMC Research Notes 2022 15:89
  37. Menopausal status impacts risk for many health outcomes. However, factors including hysterectomy without oophorectomy and Menopausal Hormone Therapy (MHT) can mask menopause, affecting reliability of self-repo...

    Authors: Sarsha Yap, Amy Vassallo, David E. Goldsbury, Usha Salagame, Louiza Velentzis, Emily Banks, Dianne L. O’Connell, Karen Canfell and Julia Steinberg
    Citation: BMC Research Notes 2022 15:88
  38. A single study conducted about three decades ago on hepatitis D virus (HDV) infection among Baka pygmies in Cameroon reported a very high anti-HDV antibodies prevalence of 46%, but HDV genetic diversity has no...

    Authors: Yacouba Foupouapouognigni, Jacques Delors Toumansie Mfonkou, Onana Boyomo, Antoine Gessain and Richard Njouom
    Citation: BMC Research Notes 2022 15:87
  39. The COVID-19 pandemic has caused widespread illness and a significant proportion of the infected required hospitalisation for treatment. People in developing countries like India were vulnerable to high hospit...

    Authors: Samir Garg, Kirtti Kumar Bebarta, Narayan Tripathi and C. Krishnendhu
    Citation: BMC Research Notes 2022 15:86
  40. Cholera is an intestinal infection caused by Vibrio cholerae, it is usually occurs in developing countries that lack of sanitation. In developing country including Indonesia, awareness importance of sanitation is...

    Authors: Andrea Budiman, Kevin Kurnia and Diana E. Waturangi
    Citation: BMC Research Notes 2022 15:63
  41. We developed an actuator-driven pulsed water jet (ADPJ) device to achieve maximal lesion dissection with minimal risk of normal structural damage. Despite the unique dissection characteristics, there is a risk...

    Authors: Sosuke Kageyama, Atsuhiro Nakagawa, Tomohiro Kawaguchi, Kiyonobu Ohtani, Toshiki Endo, Manabu Kyan, Tetsuya Kusunoki, Yoshiteru Shimoda, Shin-Ichiro Osawa, Masayuki Kanamori, Niizuma Kuniyasu and Teiji Tominaga
    Citation: BMC Research Notes 2022 15:85
  42. Streptococcus mutans is one of the principal causative agents of dental caries (tooth decay) found in the oral cavity. Therefore, this study investigates whether selenium nanoparticles (SeNPs) enhance the efficac...

    Authors: Samane Shahmoradi, Aref Shariati, Seyed Mohammad Amini, Nazanin Zargar, Zahra Yadegari and Davood Darban-Sarokhalil
    Citation: BMC Research Notes 2022 15:84
  43. From previous studies, it is known that the association between fibromyalgia and thyroid autoimmunity diseases exists. On the other hand, it was recently suggested that in many cases thyroid hormone treatment ...

    Authors: Varinen Aleksi, Kosunen Elise and Tuomas H. Koskela
    Citation: BMC Research Notes 2022 15:83
  44. To establish reference data on required competition age regarding performance levels for both sexes, all swimming strokes, and race distances and to determine the effect of competition age on swimming performa...

    Authors: Dennis-Peter Born, Ina Stäcker, Michael Romann and Thomas Stöggl
    Citation: BMC Research Notes 2022 15:82
  45. Antibiotics (ABX) are widely used for life-threatening infections and also for routine surgical operations. Compelling evidence suggests that ABX-induced alterations of gut microbiota composition, termed dysbi...

    Authors: Andrew Rodenhouse, M. A. Hassan Talukder, Jung Il Lee, Prem Kumar Govindappa, Mary O’Brien, Kristen M. Manto, Kelsey Lloyd, Grant D. Wandling, Justin R. Wright, Jeremy R. Chen See, Samantha L. Anderson, Regina Lamendella, John P. Hegarty and John C. Elfar
    Citation: BMC Research Notes 2022 15:80
  46. It has been postulated that social and economic inequalities may shape the distributions of comorbid diabetes and mental illness. This observational cohort study using linked population-based administrative an...

    Authors: Neeru Gupta, Dan Lawson Crouse and Ismael Foroughi
    Citation: BMC Research Notes 2022 15:79

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