Articles

Behind every great research project is great data management

Research data management (RDM) is the cornerstone of a successful research project, and yet it often remains an underappreciated art that gets overlooked in the hustle and bustle of everyday project management...

Authors: Samantha Kanza and Nicola J. Knight

Understanding bias when estimating life expectancy from age at death: a simulation approach applied to Morquio syndrome A

Life expectancy can be estimated accurately from a cohort of individuals born in the same year and followed from birth to death. However, due to the resource-consuming nature of following a cohort prospectivel...

Authors: Xue Yin, Jaeil Ahn and Simina M. Boca

Occupational performance of children with autism spectrum disorder and quality of life of their mothers

Limited studies were found to investigate the occupational performance of autistic children and their parents’ quality of life. Therefore, this study aimed to investigate occupational performance of children w...

Authors: Seyedeh Zeinab Beheshti, Seyed-Sirvan Hosseini, Saman Maroufizadeh and Amir Almasi-Hashiani

Comparison of insertion time, pull-out strength, and screw-media interface area of customized pedicle screw with different core and thread design against commercial pedicle screw: a pilot study on Indonesian Population

This research aimed to developing customized pedicle screw based on Indonesian vertebral anatomy and compare the insertion time, pull-out strength, and screw-media interface area of different screw design. We ...

Authors: Rahadyan Magetsari, Tedjo Rukmoyo, Marda Ade Saputra and Yudha Mathan Sakti

Six-sigma and quality planning of TORCH tests in the Peruvian population: a single-center cross-sectional study

To ensure the health of newborns, it is necessary to perform high-quality diagnostic tests. The TORCH panel is a set of tests that identifies infectious pathogens such as Toxoplasma (Toxo) and Cytomegalovirus ...

Authors: Jeel Moya-Salazar, Bianca M. SantaMaria, Marcia M. Moya-Salazar, Víctor Rojas-Zumaran, Karina Chicoma-Flores and Hans Contreras-Pulache

Development and characterization of microsatellite markers for the French endemic Angelica heterocarpa (Apiaceae) and congeneric sympatric species

Angelica heterocarpa (Apiaceae) is a wild endemic French species with special conservation interest in the European Union. It belongs to Angelica complex genus which is widespread throughout the north temperate z...

Authors: Emmanuelle Revardel and Olivier Lepais

Using parallel pre-trained types of DCNN model to predict breast cancer with color normalization

Breast cancer is the most common among women, and it causes many deaths every year. Early diagnosis increases the chance of cure through treatment. The traditional manual diagnosis requires effort and time fro...

Authors: William Al Noumah, Assef Jafar and Kadan Al Joumaa

The relationship between dietary sulfur amino acids intake and severity and frequency of pain in Iranian patients with musculoskeletal pains, 2020

Musculoskeletal pain conditions (MPs) are a widespread public problem that can affect 13.5% to 47% of the total population. Dietary changes can have strong effects on person’s health; for instance, Sulfur amin...

Authors: Niki Bahrampour, Ariyo Movahedi, Abolghassem Djazayery and Cain C. T. Clark

Expression of angiogenic markers in jawbones and femur in a rat model treated with zoledronic acid

This study aimed to investigate the gene expression of angiogenic marker in surgically treated jawbones and femur on a rat model administrated with zoledronic acid.

Authors: Jing Wen Li, Jing Yi Wang, Ru Qing Yu, Lei Huo and Li Wu Zheng

Attitude and communication skills of German medical students

While the development of communication competencies in medical schools plays a pivotal role in the curriculum, studies show that students’ communication skills and patient-centred attitudes may vary based on g...

Authors: Oana R. Groene, Maren Ehrhardt and Corinna Bergelt

A dataset for dental anxiety and psychological distress in 1550 patients visiting dental clinics

Information was collected to identify anxiety in dental patients visiting a dental clinic using the Dental Anxiety Scale, their level of psychological distress using the Brief Symptom Inventory-18 and identify...

Authors: Alexander Zinke, Christin Bohl and Hendrik Berth

Survey participation among general practitioners: comparison between teaching physicians and a random sample

Health scientists strive for a smooth recruitment of physicians for research projects like surveys. Teaching physicians are an easy to approach population that is already affiliated with a university by teachi...

Authors: Michael Pentzek, Verena Baumgart and Flora-Marie Hegerath

CRISPR/Cas9 genome editing system confirms centriolin’s role in cytokinesis

In addition to its function as the microtubule organizing center of the cell, the centrosome has functions in many other cellular processes including primary cilia formation, DNA damage checkpoints, and cell c...

Authors: Eric Seronick, Jae Son, Cameron Michael, Hannah Fogg, Zeynep Gromley and Adam Gromley

Carotid artery velocity time integral and corrected flow time measured by a wearable Doppler ultrasound detect stroke volume rise from simulated hemorrhage to transfusion

Doppler ultrasonography of the common carotid artery is used to infer stroke volume change and a wearable Doppler ultrasound has been designed to improve this workflow. Previously, in a human model of hemorrha...

Authors: Jon-Émile S. Kenny, Igor Barjaktarevic, David C. Mackenzie, Mai Elfarnawany, Zhen Yang, Andrew M. Eibl, Joseph K. Eibl, Chul-Ho Kim and Bruce D. Johnson

Identification of the role of oral health educators in elementary schools during COVID-19 pandemic: a competency framework

Oral health educators should have the required knowledge, skills and attitude in order to meet the increased needs of the Ministry of Education in Syria as well as to perform their duties in promoting oral hea...

Authors: Adel Khiami and Mayssoon Dashash

Update on prevalence of diagnosed systemic lupus erythematosus (SLE) by major health insurance types in the US in 2016

To provide current estimates of the number of patients with prevalent systemic lupus erythematosus (SLE) by major health insurance types in the US and to describe patient characteristics. Four large US health ...

Authors: Yiting Wang, Laura L. Hester, Jennifer Lofland, Shawn Rose, Chetan S. Karyekar, David M. Kern, Margaret Blacketer, Kourtney Davis and Kimberly Shields-Tuttle

Proof-of-concept and concurrent validity of a prototype headset to assess peak oxygen uptake without a face mask

Portable gas exchange instruments allow the assessment of peak oxygen uptake (V̇O_2peak) but are often bulky, expensive and require wearing a face mask thereby limiting their routine application. A newly developed...

Authors: Peter Düking, Philipp Kunz, Florian A. Engel, Helena Mastek and Billy Sperlich

The sustained adverse impact of COVID-19 pandemic on mental health among pregnant women in Sri Lanka: a reassessment during the second wave

To study the change in trend of antenatal mental health and associated factors among a cohort of pregnant women during the second wave of COVID-19 using Hospital Anxiety and Depression Scale (HADS). Previous s...

Authors: Malitha Patabendige, Dhanushka Wanniarachchi, Malika Weerasinghe, Pramith Ruwanpathirana, DMCS Jayasundara and Asanka Jayawardane

Examining the association between opium use, cigarette smoking and alcohol consumption with the liver enzyme levels in a population-based study: Fasa Persian cohort data

Opium use, cigarette smoking, and alcohol consumption are serious health problems in many countries including Iran. The present study aimed to examine the association between the opium use, cigarette smoking a...

Authors: Mostafa Bijani, Azizallah Dehghan, Saeed Razavi and Shahnaz Karimi

Translating research to usual care of children with sickle cell disease in Northern Nigeria: lessons learned from the SPRING Trial Team

Evidence-based practice for stroke prevention in high-income countries involves screening for abnormal transcranial Doppler (TCD) velocity and initiating regular blood transfusions for at least 1 year, followe...

Authors: Halima Bello-Manga, Lawal Haliru, Abdulkadir M. Tabari, Bilkisu Farouk, Aisha Suleiman, Gloria Y. Bahago, Abdulrasheed M. Sani, Ana A. Bauman, Michael R. DeBaun and Allison A. King

Correction to: COVID-19 vaccine preferences among university students in Hong Kong: a discrete choice experiment

Authors: Xue Li, Man Yui Chong, Ching Yui Chan, Vindy Wing Sum Chan and Xinning Tong

Establishment of a simple method to evaluate mixing times in a plastic bag photobioreactor using image processing based on freeware tools

Accurate determination of the mixing time in bioreactors is essential for the optimization of the productivity of bioprocesses. The aim of this work was to develop a simple optical method to determine the mixi...

Authors: Henrike Wurm and Michael Sandmann

Preliminary demonstration of benchtop NMR metabolic profiling of feline urine: chronic kidney disease as a case study

The use of benchtop metabolic profiling technology based on nuclear magnetic resonance (NMR) was evaluated in a small cohort of cats with a view to applying this as a viable and rapid metabolic tool to support...

Authors: Natalie Finch, Benita Percival, Elena Hunter, Robin J. Blagg, Emily Blackwell, James Sagar, Zeeshan Ahmad, Ming-Wei Chang, John A. Hunt, Melissa L. Mather, Séverine Tasker, Luisa De Risio and Philippe B. Wilson

The geography of COVID-19 misinformation: using geospatial maps for targeted messaging to combat misinformation on COVID-19, South Africa

The proliferation of false information on COVID-19 mostly through social media is adversely affecting control efforts. The objective of this study was to identify areas where targeted effective messaging can b...

Authors: Lucy Chimoyi, Tonderai Mabuto, Tanyaradzwa Dube, Nasiphi Ntombela, Tshegang Nchachi, Dakalo Tshisebe, Candice M. Chetty-Makkan and Geoffrey K. Setswe

Creating a positive perception toward inclusive education with future-oriented thinking

The purpose of this study was to examine the ways that encouraged people to develop positive attitudes and perceptions toward inclusive education. The Japanese special needs education system for students with ...

Authors: Kaede Maeda, Hirofumi Hashimoto and Kosuke Sato

Complete genome sequencing of SARS-CoV-2 strains: A pilot survey in Palestine reveals spike mutation H245N

SARS-CoV-2, severe respiratory syndrome coronavirus-2, is an RNA virus that emerged from China sweeping the globe in the form of a pandemic that became an international public health concern. This pilot study ...

Authors: Amer Al-Jawabreh, Suheir Ereqat, Kamal Dumaidi, Hanan Al-Jawabreh and Abedelmajeed Nasereddin

Effects of balance training on static and dynamic balance performance in healthy children: role of training duration and volume

Improvements in balance performance through balance training programs in children have been reported in several studies. However, the influence of balance training modalities (e.g., training period, frequency,...

Authors: Thomas Muehlbauer

Adolescent suicide attempts in three diverse island nations: patterns, contextual differences and demographic associations

Most epidemiological studies on suicidal behavior have been focused on high-income country settings. This study examine factors associated with suicidal behaviors among school-attending adolescents in three is...

Authors: Jinrong Fu, Olumide Abiodun, Michael Lowery Wilson and Masood Ali Shaikh

Data on the Facebook marketing strategies used by fast-food chains in four Latin American countries during the COVID-19 lockdowns

During the COVID-19 pandemic, most countries implemented lockdowns that motivated changes in the dietary patterns, physical activity, and body mass index (BMI) of consumers worldwide, as well as the emergence ...

Authors: Lucila Rozas, Luciana Castronuovo, Peter Busse, Sophia Mus, Joaquín Barnoya, Alejandra Garrón, María Victoria Tiscornia and Leila Guanieri

Would you like to be contacted about future research?

Many research participants are willing to be contacted about future research opportunities, however this question is not always asked. Furthermore, if participants do consent for contact about future research,...

Authors: Lisa Newington, Caroline M. Alexander and Mary Wells

Ecological surveillance of bat coronaviruses in Sarawak, Malaysian Borneo

Coronaviruses (CoVs) are natural commensals of bats. Two subgenera, namely Sarbecoviruses and Merbecoviruses have a high zoonotic potential and have been associated with three separate spillover events in the ...

Authors: Cheng-Siang Tan, Vaenessa Noni, Jaya Seelan Sathiya Seelan, Azroie Denel and Faisal Ali Anwarali Khan

The evolved divergence of γ-secretase-susceptibility of homologous proteins Ngfrb and Nradd in zebrafish

NGFR/p75NTR and NRADD/NRH proteins are closely related structurally and are encoded by genes that arose from a duplication event early in vertebrate evolution. The transmembrane domain (TMD) of NGFR is cleaved...

Authors: Tanya Jayne, Morgan Newman, Lachlan Baer and Michael Lardelli

Genomic characterization of bacteriophage BI-EHEC infecting strains of Enterohemorrhagic Escherichia coli

The aims of this research were to determine the genomic properties of BI-EHEC to control Enterohemorrhagic Escherichia coli (EHEC), which was isolated from previous study. Genomic analysis of this phage is essent...

Authors: Marta Nisita Dewanggana, Diana Elizabeth Waturangi and Yogiara

Improving research quality: the view from the UK Reproducibility Network institutional leads for research improvement

The adoption and incentivisation of open and transparent research practices is critical in addressing issues around research reproducibility and research integrity. These practices will require training and fu...

Authors: Andrew J. Stewart, Emily K. Farran, James A. Grange, Malcolm Macleod, Marcus Munafò, Phil Newton and David R. Shanks

In-silico analysis reveals druggable single nucleotide polymorphisms in angiotensin 1 converting enzyme involved in the onset of blood pressure

The Angiotensin 1 converting enzyme (ACE1) gene plays a critical role in regulating blood pressure and thus, it has become a major therapeutic target of antihypertensives. Single nucleotide polymorphisms (SNPs) o...

Authors: Brenda Udosen, Opeyemi Soremekun, Chinwe Ekenna, Olaposi Idowu Omotuyi, Tinashe Chikowore, Oyekanmi Nashiru and Segun Fatumo

Nuclear matrix associated RNA datasets of posterior silk glands of Bombyx mori during 5th instar larval development

Bombyx mori is the key contributor to industrial silk production. The maximum production of silk occurs during 5th instar. The posterior silk glands in the larvae are responsible for the production of the main co...

Authors: Alekhya Rani Chunduri, Anugata Lima, Resma Rajan and Anitha Mamillapalli

Impacts of FcγRIIB and FcγRIIIA gene polymorphisms on systemic lupus erythematous disease activity index

Systemic lupus erythematous (SLE) disease is a chronic autoimmune disease with unknown etiology that can involve different organs. Polymorphisms in Fcγ receptors have been identified as genetic factors in susc...

Authors: Mansoor Karimifar, Khosro Akbari, Reza ArefNezhad, Farshid Fathi, Mohammad Moosaeepour and Hossein Motedayyen

Bixin and fucoxanthin sensitize human lung cancer and cervical cancer cell to cisplatin in vitro

Cisplatin is a conventional anticancer drug that generates reactive oxygen species and causes apoptosis. However, many cancer cells develop alterations in the ATP binding cassette transporter responsible for t...

Authors: Agustina Dwi Retno Nurcahyanti, Lia Kusmita and Michael Wink

Predicting the success of induction of labour using cervical volume

Assessing the likelihood of success of induction of labour using cervical volume is an important research question.

Authors: Malitha Patabendige and Sanka Rajesh Athulathmudali

Association between induction of the self-management system for preventing readmission and disease severity and length of readmission in patients with heart failure

We recently developed the self-management system using the HF points and instructions to visit hospitals or clinics when the points exceed the pre-specified levels. We found that the self-management system dec...

Authors: Eisaku Nakane, Takao Kato, Nozomi Tanaka, Tomoari Kuriyama, Koki Kimura, Shushi Nishiwaki, Toka Hamaguchi, Yusuke Morita, Yuhei Yamaji, Yoshisumi Haruna, Tetsuya Haruna and Moriaki Inoko

Reproducibility and research integrity: the role of scientists and institutions

Reproducibility and research integrity are essential tenets of every scientific study and discovery. They serve as proof that an established and documented work can be verified, repeated, and reproduced. New k...

Authors: Patrick Diaba-Nuhoho and Michael Amponsah-Offeh

RNA-seq analysis identified glucose-responsive genes and YqfO as a global regulator in Bacillus subtilis

We observed that the addition of glucose enhanced the expression of sigX and sigM, encoding extra-cytoplasmic function sigma factors in Bacillus subtilis. Several regulatory factors were identified for this pheno...

Authors: Yu Kanesaki and Mitsuo Ogura

Lipid A-Ara4N as an alternate pathway for (colistin) resistance in Klebsiella pneumonia isolates in Pakistan

This study aimed to explore mechanism of colistin resistance amongst Klebsiella pneumoniae isolates through plasmid mediated mcr-1 gene in Pakistan. Carbapenem and Colistin resistant K. pneumoniae isolates (n  = ...

Authors: Kiran Iqbal Masood, Seema Umar, Zahra Hasan, Joveria Farooqi, Safina Abdul Razzak, Nazish Jabeen, Jason Rao, Sadia Shakoor and Rumina Hasan

Mangifera indica as propolis source: what exactly do bees collect?

The mango tree Mangifera indica is known as one of the botanical sources of propolis in Tropical regions. There are two different materials which bees can collect from a mango tree to produce propolis: the resin ...

Authors: Milena Popova, Boryana Trusheva, Nia Ilieva, Le Nguyen Thanh, Nguyen Thi Phuong Lien and Vassya Bankova

Interferon-γ induces interleukin-6 production by neutrophils via the Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway

Interferon-gamma (IFN-γ) is overexpressed in rheumatoid synovium and thought to be involved in the pathogenesis of rheumatoid arthritis (RA). In this study, we examined our hypothesis that IFN-γ activates inna...

Authors: Shuhei Yoshida, Shunya Yamada, Kohei Yokose, Haruki Matsumoto, Yuya Fujita, Tomoyuki Asano, Naoki Matsuoka, Jumpei Temmoku, Shuzo Sato, Makiko Yoshiro-Furuya, Hiroshi Watanabe and Kiyoshi Migita

Accelerated nonstandard finite difference method for singularly perturbed Burger-Huxley equations

The main purpose of this paper is to present an accelerated nonstandard finite difference method for solving the singularly perturbed Burger-Huxley equation in order to produce more accurate solutions.

Authors: Masho Jima Kabeto and Gemechis File Duressa

Teaching reproducible research for medical students and postgraduate pharmaceutical scientists

In medicine and other academic settings, (doctoral) students often work in interdisciplinary teams together with researchers of pharmaceutical sciences, natural sciences in general, or biostatistics. They shou...

Authors: Andreas D. Meid

Performance comparison of gel and capillary electrophoresis-based microsatellite genotyping strategies in a population research and kinship testing framework

The advancement of molecular techniques in an era in which high-throughput sequencing has revolutionized biology renders old-fashioned alternatives to high-throughput methods obsolete. Such advanced molecular ...

Authors: Julissa J. Sánchez-Velásquez, Lorenzo E. Reyes-Flores, Carmen Yzásiga-Barrera and Eliana Zelada-Mázmela

Hypothalamic-pituitary hormones will be affected by the interaction between 5q13-14-rs2239670 (CARTPT) gene variants and diet in different obesity phenotypes

Evidence show that cocaine and amphetamine regulated transcript-prepropeptide (CART-PT) gene variants may affect obesity related traits, but little is known about its end points. In the current study, we aimed...

Authors: Mahsa Mahmoudinezhad, Mahdieh Abbasalizad-Farhangi and Houman Kahroba

RT-QuIC detection of pathological prion protein in subclinical goats following experimental oral transmission of L-type BSE

The spread of bovine spongiform encephalopathy (BSE) agent to small ruminants is still a major issue in the surveillance of transmissible spongiform encephalopathies (TSEs). L-type bovine spongiform encephalop...

Authors: Alessandra Favole, Maria Mazza, Antonio D’Angelo, Guerino Lombardi, Claudia Palmitessa, Luana Dell’Atti, Giulia Cagnotti, Elena Berrone, Marina Gallo, Tiziana Avanzato, Erika Messana, Loretta Masoero, Pier Luigi Acutis, Daniela Meloni, Franco Cardone, Maria Caramelli…